Research suggests that green tea supports healthy weight management, antioxidant defense and liver function, and we have combined it with carnitine to help enhance its effects. We use the uniquely researched green tea phytosome, a phospholipid-bound form of green tea that is the most highly absorbed form of green tea yet developed.
Green Tea Phytosome?................................................400 mg
Other Ingredients: gelatin, water, silicon dioxide, cellulose.
Read Customer questions and answers about Weight Loss in our FAQ.
Important Synergy for Two Therapeutic Nutrients
Carnitine is one of the most important nutrients needed for maintaining and promoting health, with over 158 clinical trials performed in humans.[1] Much of the clinical benefit of carnitine derives from the fact that carnitine is essential for fat burning and therefore energy production in nearly all cells. Carnitine promotes cellular energy by transporting fatty acids into the mitochondria, the powerhouses of our cells, where they are burned for energy. Just as importantly, carnitine also removes metabolic wastes from the mitochondria to keep them smooth running.[2]
Because the heart derives 70% of its energy from fat, and carnitine is needed for fat burning, it comes as no surprise that carnitine is crucial for heart health and offers important nutritional support for many heart conditions, including angina.[3] Carnitine supplementation has also been found to reduce complications and overall deaths dramatically in patients in the four weeks directly following a heart attack.[4]
Who Can Benefit from Carnitine
Those who want to burn fat more efficiently.
Older adults, helping them to experience less fatigue in body and mind and engage in more daily activities.[5] Carnitine supplements also help healthy elderly subjects reduce their total fat mass, increase their total muscle mass, improve their overall feeling of wellness and lower lipid levels dramatically.[6] In a landmark paper, carnitine was also found to help support erectile function and healthy mood levels in older men.[7]
Diabetics, as it helps lower fasting blood sugar[8] and lipoprotein(a) levels[9] in these patients.
Pregnant women, as their carnitine levels are lowered due to the high carnitine requirements of the fetus, especially in the last two trimesters.[10] This can often lead to low levels of carnitine in the mother.[11]
Vegetarians also have lower levels of carnitine.[12] Because children have increased carnitine needs, strict vegetarian diets in children should always be accompanied by carnitine supplementation.[13]
Those undergoing dialysis, but it should be used only with close medical supervision in this condition as the nutrient requirements of each dialysis patient are unique.[14] Carnitine also helps lower Creactive protein levels in dialysis patients.[15]
Cancer and cachexia: Carnitine provides valuable nutritional support in these patients, helping to promote optimal lean body mass, energy levels, and overall quality of life.[16] Further research supports these findings, and also shows that most cancer patients are carnitine deficient.[17]
Those with chronic obstructive pulmonary disease: Carnitine supplementation increases exercise tolerance and inspiratory muscle strength in these patients according to one study.[18] Hyperthyroid: Carnitine helps support bone health and overall wellness in hyperthyroid patients,[19] and is especially useful during thyroid storm, a condition which depletes carnitine from the body.[20] For a full discussion with the pioneering researcher in hyperthyroid and carnitine, Dr. Salvatore Benvenga,[21] download Robert Crayhon?s interview with him at www.CrayhonResearch.com.
Men who seek nutritional support for sperm health.[22]
Those with anemia, as carnitine supports red blood cell wall integrity.[23]
HIV patients, as carnitine supports healthy immune function in these patients.[24]
Those with high blood pressure, as it helps maintain healthy blood pressure levels.[25]
Multiple Sclerosis patients, as it increases their energy levels and well-being.[26]
Those who exercise: Numerous studies show that carnitine helps suppress the muscle damage that can occur during exercise[27] and speeds recovery from exercise.[28]
Medications Increase Need for Carnitine
Many drugs increase the need for carnitine, and their side effects can often be reduced by using carnitine simultaneously. These include valproic acid[29], isotretinion,[30] interferon[31] doxorubicin,[32] and adriamycin.[33]
Why Add Biotin to Carnitine?
While carnitine supports fat burning, it can also stimulate gluconeogenesis,[34] which is the liver?s over-production of sugar. Biotin helps suppress gluconeogenesis,[35] thus helping to optimize the metabolic effect of carnitine. Therefore, when using carnitine to support fatty acid oxidation, we strongly recommend taking 1 mg of biotin for every 500 mg of carnitine to keep gluconeogenesis and insulin metabolism balanced.
Crayhon R. The carnitine miracle : the supernutrient program that promotes high energy, fat burning, heart health, brain wellness, and longevity. New York: M. Evans; 1998.
Alesci S. Carnitine : the science behind a conditionally essential nutrient. NewYork, N.Y.: NewYork Academy of Sciences; 2004.
Ferrari R, Cucchini F, Visioli O. The metabolical effects of L-carnitine in angina pectoris. International journal of cardiology. 1984 Feb;5(2):213-6.
Singh RB, Niaz MA, Agarwal P, Beegum R, Rastogi SS, Sachan DS. A randomised, double-blind, placebo-controlled trial of L-carnitine in suspected acute myocardial infarction. Postgraduate medical journal. 1996 Jan;72(843):45-50.
Malaguarnera M, Di Mauro A, Gargante PM, Rampello L. L-carnitine reduces severity of physical and mental fatigue and improves daily activities in the elderly. Southern medical journal. 2006 Mar;99(3):315-6.
Pistone G, Marino A, Leotta C, Dell'Arte S, Finocchiaro G, Malaguarnera M. Levocarnitine administration in elderly subjects with rapid muscle fatigue: effect on body composition, lipid profile and fatigue. Drugs & aging. 2003;20(10):761-7.
Cavallini G, Caracciolo S, Vitali G, Modenini F, Biagiotti G. Carnitine versus androgen administration in the treatment of sexual dysfunction, depressed mood, and fatigue associated with male aging. Urology. 2004 Apr;63(4):641-6.
Rahbar AR, Shakerhosseini R, Saadat N, Taleban F, Pordal A, Gollestan B. Effect of Lcarnitine on plasma glycemic and lipidemic profile in patients with type II diabetes mellitus. European journal of clinical nutrition. 2005 Apr;59(4):592-6.
Derosa G, Cicero AF, Gaddi A, Mugellini A, Ciccarelli L, Fogari R. The effect of Lcarnitine on plasma lipoprotein(a) levels in hypercholesterolemic patients with type 2 diabetes mellitus. Clinical therapeutics. 2003 May;25(5):1429-39.
Plasma carnitine concentrations in pregnancy, cord blood, and neonates and children. Clinica chimica acta; international journal of clinical chemistry. 1995 Dec 15;243(1):87-93.
Bargen-Lockner C, Hahn P, Wittmann B. Plasma carnitine in pregnancy. American journal of obstetrics and gynecology. 1981 Jun 15;140(4):412-4.
Carnitine status of lactoovovegetarians and strict vegetarian adults and children. The American journal of clinical nutrition. 1989 Aug;50(2):301-6.
Systemic carnitine deficiency exacerbated by a strict vegetarian diet. Archives of disease in childhood. 1984 Feb;59(2):177-9.
Debate forum: levocarnitine therapy is rational and justified in selected dialysis patients. Blood purification. 2006;24(1):128-39.
L-carnitine infusions may suppress serum C-reactive protein and improve nutritional status in maintenance hemodialysis patients. J Ren Nutr. 2005 Apr;15(2):225-30.
Efficacy of l-carnitine administration on fatigue, nutritional status, oxidative stress, and related quality of life in 12 advanced cancer patients undergoing anticancer therapy. Nutrition (Burbank, Los Angeles County, Calif. 2006 Feb;22(2):136-45.
Cruciani RA, Dvorkin E, Homel P, Malamud S, Culliney B, Lapin J, et al. Safety, tolerability and symptom outcomes associated with L-carnitine supplementation in patients with cancer, fatigue, and carnitine deficiency: a phase I/II study. Journal of pain and symptom management. 2006 Dec;32(6):551-9.
L-carnitine as an ergogenic aid for patients with chronic obstructive pulmonary disease submitted to whole-body and respiratory muscle training programs. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica [et al. 2006 Apr;39(4):465-74.
Effects of L-carnitine on thyroid hormone metabolism and on physical exercise tolerance. Hormone and metabolic research Hormon?und Stoffwechselforschung. 2005 Sep;37(9):566-71.
Effects of carnitine on thyroid hormone action. Annals of the New York Academy of Sciences. 2004 Nov;1033:158-67.
Crayhon R. Carnitine for Hyperthyroid: An Interview with Salvatore Benvenga, MD. Nutritional Medicine Update. 2003.
Placebo-controlled double-blind randomized trial on the use of L-carnitine, L-acetylcarnitine, or combined Lcarnitine and L-acetylcarnitine in men with idiopathic asthenozoospermia. Fertility and sterility. 2005 Sep;84(3):662-71.
L-carnitine treatment of anemia. Am J Kidney Dis. 2003 Apr;41(4 Suppl 4):S27-34.
High dose L-carnitine improves immunologic and metabolic parameters in AIDS patients. Immunopharmacology and immunotoxicology. 1993 Jan;15(1):1-12.
L-carnitine adjuvant therapy in essential hypertension. La Clinica terapeutica. 1994 May;144(5):391-5.
Levocarnitine administration in multiple sclerosis patients with immunosuppressive therapy-induced fatigue. Multiple sclerosis (Houndmills, Basingstoke, England). 2006 Jun;12(3):321-4.
Spiering BA, Kraemer WJ, Vingren JL, Hatfield DL, Fragala MS, Ho JY, et al. Responses of criterion variables to different supplemental doses of L-carnitine L-tartrate. Journal of strength and conditioning research / National Strength & Conditioning Association. 2007 Feb;21(1):259-64.
L-Carnitine Ltartrate supplementation favorably affects markers of recovery from exercise stress. American journal of physiology. 2002 Feb;282(2):E474-82.
The effect of carnitine supplementation in valproateinduced hyperammonaemia. Acta Paediatr. 1996 Apr;85(4):446-9.
L-carnitine supplementation in patients with cystic acne on isotretinoin therapy. J Eur Acad Dermatol Venereol. 1999 Nov;13(3):205-9.
Neri S, Pistone G, Saraceno B, Pennisi G, Luca S, Malaguarnera M. L-carnitine decreases severity and type of fatigue induced by interferon-alpha in the treatment of patients with hepatitis C. Neuropsychobiology. 2003;47(2):94-7.
Reduction of cardiac toxicity of anthracyclines by L-carnitine: preliminary overview of clinical data. International journal of clinical pharmacology research. 1985;5(2):137-42.
Acute and chronic effects of adriamycin on fatty acid oxidation in isolated cardiac myocytes. Journal of molecular and cellular cardiology. 1997 Feb;29(2):789-97.
Modern nutrition in health and disease. 10th ed. Philadelphia: Lippincott Williams & Wilkins; 2006.
Pharmacological effects of biotin. The Journal of nutritional biochemistry. 2005 Jul;16(7):424-7.
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