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Carnosine Supreme by Designs For Health (DFH) 

Carnosine Supreme by Designs For Health (DFH)
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About Carnosine Supreme by Designs For Health (DFH)

Carnosine Supreme is a synergistic combination of two powerful naturally occurring anti-glycating and anti-aging agents, carnosine and benfothiamine. Carnosine Supreme is often recommended by doctors for people with diabetes who are most at risk for the health concerns related to accelerated aging.

Carnosine (not to be confused with 'carnitine') is a combination of two amino acids (building blocks of proteins), alanine and histidine. It is naturally present in tissues like muscle and brain, but its concentration falls with advancing age. In laboratory studies, it has been demonstrated that carnosine has the ability to protect cells against oxidative stress as well as to increase their resistance toward functional exhaustion and accumulation of senile features. Benefits proven in studies with a dose of carnosine ranging from 800 mg/day to 25 mg/lb. body weight include:

  • Universal and versatile antioxidant activity
  • Increasing muscle strength and endurance
  • Speeding up recovery after sprints
  • Inhibiting cellular damage caused by alcohol
  • Speeds up wound healing by stimulating collagen production
  • Restores youthful appearance in skin cells
  • Protective on eyesight, especially aging related impairment

Carnosine as a multifunctional dietary supplement is a relatively new discovery. It is an amazing physiological and 100 % natural super-antioxidant with numerous biological roles. Benfothiamine (S-benzoylthiamin-o-monophosphate) is a highly efficient fat soluble form of Thiamin (vitamin B1) and occurs naturally in small amounts in crushed garlic, shallots and leeks. Its use began in Japan in the late 1950's to treat alcoholic neuropathy, sciatica and other painful nerve conditions. It was patented in the U.S. in 1962, and has been in widespread use in Japan since 1962 and in Europe since 1992 with encouraging results. It reduces glycation products caused by excessively high glucose/fructose levels, especially inside endothelial, retinal, kidney and nerve cells.


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Read Customer questions and answers about Other Health Concerns in our FAQ.


More Info about Carnosine Supreme by Designs For Health (DFH)
Why do we need supplemental carnosine?
Carnosine levels in the body decline with age. Muscle levels decrease 63% from age ten to age seventy, which may account for the reduction in muscle mass and function seen in aging humans. In addition, a major dietary source of carnosine is meat, and many people are cutting down or eliminating meat consumption. The multiplicity of pathological effects caused by protein degradation places this problem beyond the scope of simple antioxidants. Carnosine is the most promising broad-spectrum shield against protein degradation.

What is the right amount of carnosine to consume each day?
It is critical to take the proper amount of carnosine each day in order to obtain a life extension effect. The reason for this is that the body produces an enzyme called carnosinase that degrades dietary carnosine. By taking at least 1,000mg a day of supplemental carnosine, you safely overwhelm the body’s degradation enzymes and provide your cells enough carnosine to derive the benefits eluded in the published research. Commercial supplement companies offer carnosine in 50mg strength tablets. This dose provides limited benefit because the carnosine is degraded by the carnosinase enzyme before it can produce beneficial effects in the body.

Extended Cell Life
In a series of experiments at a research institute in Australia, scientists showed that carnosine rejuvenates cells approaching senescence. Human lung and foreskin fibroblasts cultured with carnosine that had gone through many stages of replication lived longer and retained a youthful appearance and growth patterns compared to control cells that were the same “age” without added carnosine. Late-passage fibroblasts placed in a culture medium with added carnosine actually showed a rejuvenated appearance and often an enhanced capacity to divide. When the same rejuvenated fibroblasts were re-transferred to a culture without carnosine, they soon became senescent again! How does carnosine revitalize cells in culture? Some researchers propose that carnosine may rejuvenate cells by reducing the formation of abnormal proteins, or by stimulating the removal of old patterns.

Aging Process
Carnosine has several important functions related to the Aging Process. Specifically, it maintains the defense mechanisms of fibroblasts, inhibits cross-linking and improves the efficiency of the synthesis of endogenous proteins.

In another study, late-passage fibroblasts transferred to a carnosine medium lived 413 days, compared to control cells that lived 126 to 139 days. These results show a dramatic increase in potential lifespan.

Carnosine: A Powerful Anti-Aging Nutrient

Antioxidant
Carnosine functions as an antioxidant in cell membranes and prevents lipid peroxidation within cell membranes. It acts not only as an antioxidant in muscle, but also as a pH buffer. In this way it keeps on protecting muscle cell membranes from oxidation under the acidic conditions of muscular exertion. Carnosine enables the heart muscle to contract more efficiently through enhancement of calcium response in heart cells. Carnosine has been shown to rejuvenate connective tissue cells, which may explain its beneficial effects on wound healing. Damaged proteins accumulate and cross-link in the skin, causing wrinkles and loss of elasticity.

Digestive System
Carnosine accelerates the healing of gastric mucosal cells.

Eyes and Vision
Carnosine concentrates in the lens of the eyes where it helps to slow protein cross-linking.

Nervous System
Carnosine may support brain function by inhibiting the damage caused by Amyloid-Beta Protein. Carnosine concentrates in the brain, although its function in the brain is still being defined. Natural levels of carnosine in a healthy brain may help normalize copper and zinc levels, protein cross-linking and glycation, and oxidation damage to cell membranes.

Skin
Carnosine maintains the defense mechanisms of fibroblasts and inhibits oxidative damage to fibroblasts. It accelerates the natural healing process of wounds, burns, and post-operative wounds.

Autism
In scientific research, Carnosine has beeen found to significantly increase behavior, socialization, language comprehension, and communication.

Research Summaries on Carnosine and Autism Spectrum Disorders
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Certificate of Analysis Lot 102704-CS

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