CoQ10 Q-Avail by Designs For Health (DFH) 

Supporting Heart Health
CoQ10 is one of the most important nutrients for maintaining the health of the heart. The heart contains twice as much CoQ10 as any other organ or tissue in the body. CoQ10 is needed for the heart to keep up its constant production of energy. CoQ10 can even help heal the hearts of those slated for heart transplants so that they no longer need them.[1] A wide range of heart conditions benefit from CoQ10 supplementation, including angina, mitral valve prolapse, and perhaps cardiomyopathies and congestive heart failure. Paradoxically, medications thought to promote heart health may lower CoQ10 levels. Lovastatin can decrease levels of CoQ10, sometimes to the point of leading to heart and liver damage.[2] Those on statin medications should supplement with CoQ10.

Lowering Blood Pressure
One hundred milligrams of CoQ10 per day has been found to lower blood pressure while also raising protective HDL cholesterol and lowering total cholesterol.[3]

Enhancing Immune Function
Studies indicate CoQ10 may have dramatic immune-enhancing effects. Older adults as well as those with HIV in particular may benefit from CoQ10.[4]

Promoting Gum Health
CoQ10 may help those with periodontal disease heal their gums more quickly. Topical application of CoQ10 may be more effective than taking it orally.[5]

Supporting Cancer Patients
Cancer patients taking chemotherapy drugs that are associated with heart toxicity such as adriamycin should consider CoQ10 because it can reduce the toxicity of these drugs. One human study suggested that 390 mg of CoQ10 per day may help support overall wellness and recovery in those with breast cancer.[6]

Supplement Suggestions For COQ10
The therapeutic dosage range of CoQ10 is 30 to 400 mg per day. Consuming CoQ10 with an oil or fat improves absorption unless you buy a supplement that provides the fat source along with the CoQ10. If you are taking any medications, or are using CoQ10 to help with any health condition, take it with the guidance of your health care practitioner.

A Smart and Efficient CoQ10 Supplement!
With prices of CoQ10 historically the most volatile in the supplement industry, it is essential that your CoQ10 supplement be designed with efficiency and cost effectiveness in mind. It is no longer practical to just use high doses to overcome low absorption rates. Q-Avail™ is designed and produced for higher absorption and CoQ10 stability to deliver superior clinical outcomes with more cost-efficiency than other commonly used forms of CoQ10. In a recent in-house study being prepared for publication, Q-Avail™ was demonstrated to result in higher peak absorption and higher serum CoQ10 levels after a 2-week supplementation period compared to other forms of CoQ10, including dry powder and popular sublingual forms.

Oral supplementation with CoQ10 is often desired to improve mitochondrial metabolism and energy production in the treatment of fatigue-related disorders, the enhancement of athletic performance, and the treatment of cardiomyopathy. CoQ10 has also been demonstrated to be an effective antioxidant, reducing lipid peroxidation. CoQ10 is a lipid soluble, high molecular weight, hydrophobic molecule. These molecular properties present problems with oral supplementation viability. CoQ10 has a tendency to crystallize in the stomach and is inherently difficult to absorb. As CoQ10 supplements are comparatively expensive, with costs remaining very volatile in the past few years, there is a great desire on the part of prescribing clinicians to determine the most economical form of CoQ10 which will deliver clinical efficacy. Many proprietary forms of CoQ10 commercially available claim some aspect of novelty and increased absorption, often at the expense of much higher pricing, but do they really deliver? At Designs for Health we have conducted absorbability studies to assure that Q-Avail™ truly is a superior and effective choice. DFH's in-house study compared the absorption by measuring the average increase serum CoQ10 levels over a 6-hour period and the total serum CoQ10 levels after a 2-week supplementation with 100 mg of various forms of CoQ10. A brief summary of results appears below:

CoQ10 Form	Average increase from baseline (over 6-hours)
Q-Avail™	1.23 mcg/L
Dry CoQ10 powder	0.60 mcg/L

CoQ10 Form	Average absolute increase from baseline (after 2-weeks supplementation)
Q-Avail™	1.06 mcg/L
Sublingual CoQ10	0.50 mcg/L
Dry CoQ10 powder	0.48 mcg/L

Results summary:
* Q-Avail™ 100 mg softgels resulted in a 112% greater absolute increase in serum CoQ10 than sublingual CoQ10 and a 121% greater absolute increase than dry CoQ10 powder.
* Oral supplementation with 100mg of Q-Avail™ resulted in 105% higher average increase from baseline in serum CoQ10 over 6-hours, as compared to dry CoQ10 powder.

The superior bioavailability of this CoQ10 formulation is dependent on novel technology that keeps the crystalline structure in liquid heterogeneity using bee wax, rice bran oil, D. salina; the mixed tocopherols are included in the softgel for stability. The softgel is colored naturally with annatto and tumeric and contains no artificial ingredients.

Click here to download CoQ10 PDF file: Heart Health, Immune Function, and Overall Wellness Research
Click here to download Q-Avail PDF file