Q-Avail VS 100mg (Formally Q-Avail Nano) - Our highest potency CoQ10 product, delivering 100mg of ubiquinone in a single softgel.
Q-Avail™ VS utilizes a patented, nano-emulsion delivery system that allows us to pack 100mg of CoQ10 in an easy- to-swallow softgel.
How does nano-emulsion technology work?
This technology takes an insoluble, poorly-absorbed lipophilic (fat-dissolving) ingredient like CoQ10 and water solubilizes it. Once exposed to the aqueous environment in the stomach, the material self-assembles into tiny fluid droplets. These droplets are very similar to the nano-sized fluid droplets or micelles that the body normally manages to create when digesting high-fat foods in order to make them easier to absorb.
The softgels in Q-Avail™ VS are composed of millions of these tiny nano-sized colloidal droplets of solubilized CoQ10 that are easily absorbed in the GI tract, resulting in enhanced bioavailability.
Each softgel delivers 100mg of Coenyzme Q10 (ubiquinone) and provides the same research-driven superior absorption and bioavailability found with our current line of CoQ10 products.
Benefits of CoQ10 Include:
Cholesterol Oxidation Prevention
Increases sperm coun
Serving Size: 1 softgel Servings Per Container: 60
Amount Per Serving Natural Coenzyme Q10 ... 100mg (Ubiquinone)
Other Ingredients: Hydroxypropyl methylcellulose (vegetarian capsule), patented VESIsorb® formula (medium chain triglycerides, polysorbate 80, citrus oil extract [Citrus sinensis][peel] and polyglycerol fatty acid esters), d-alpha-tocopheryl.
Recommended Use: As a dietary supplement, take one or more softgels daily with meals or as directed by your health care practitioner.
This product does not contain: fish, shellfish, peanuts, tree nuts, milk & lactose, eggs, soy protein, wheat, gluten, artificial colors.
Coenzyme Q10 (CoQ10) is a fat-soluble, high molecular weight compound produced by the body for the basic functioning of cells. It plays a central role in cellular energy metabolism that produces adenosine triphosphate (ATP), the energy currency for muscle contraction and other cellular processes. CoQ10 gets its name from the word ubiquitous because it is present everywhere in the human body.
CoQ10 Demystified... CoQ10 exists in both ubiquinone and ubiquinol forms. In mitochondrial electron transport system CoQ10 undergoes continuous reversible oxidation and reduction. It is converted to ubiquinol (reduced form) when it accepts electrons and to ubiquinone (oxidized form) when it donates electrons. In its ubiquinol form, CoQ10 functions as a potent antioxidant due to its ability to donate electrons, thus serving as a primary scavenger of free radicals.Ubiquinol is the only known lipid-soluble antioxidant present in all membranes that can be synthesized endogenously by animal and human cells with an enzymatic mechanism for regeneration from ubiquinone. Research indicates that ubiquinol is more efficient in inhibiting lipid peroxidation than alpha tocopherol, lycopene or beta-carotene.As an antioxidant, CoQ10 regulates membrane fluidity, recycles radical forms of vitamin C and E and protects membrane phospholipids against peroxidation (the process whereby free radicals "steal" electrons from the lipids in cell membranes which can result in cell damage).
Ubiquinone or Ubiquinol? Most healthy individuals are able to convert ubiquinone to ubiquinol. It has been shown that 80-95% of circulating CoQ10 following oral ingestion of a ubiquinone supplement is in the form of ubiquinol.
Why is CoQ10 Important? Low levels of CoQ10 (ubiquinone) have been documented in people experiencing various disease states including congestive heart failure, angina pectoris, coronary artery disease, cardiomyopathy, chronic obstructive pulmonary disease, Parkinson's disease, cancer, periodontal disease, asthma, age-related macular degeneration, hyperthyroidism, HIV/AIDS, cerebellar ataxia. Plasma ubiquinol is decreased in patients with hyperlipidemia and liver disease.
Medications and CoQ10 Depletion CoQ10 is synthesized in the same pathway as cholesterol, and therefore also involves the HMG CoA reductase enzyme. CoQ10 production is negatively affected by use of statin drugs because they interfere with this enzyme by design. Research suggests that some cholesterol-lowering statin drugs decrease serum CoQ10 levels by as much as 40%. Other drugs (gemfibrozil, Adriamycin, beta blockers) have been found to decrease serum CoQ10.
Who Should Take CoQ10? Supplementation with CoQ10 has been shown in research studies to provide a wide range of health benefits and may help support the following:
Neural and brain health
Genetic CoQ10 deficiencies
Biochemical functions of coenzyme Q10. Crane FL. J Am Coll Nutr. 2001 Dec;20(6):591-8.
Ubiquinol-10 is an effective lipid-soluble antioxidant at physiological concentrations. Frei B, Kim MC, Ames BN. Proc Natl Acad Sci U S A. 1990 Jun;87(12):4879-83.
Ubiquinol: an endogenous antioxidant in aerobic organisms. Ernster L, Forsmark-Andr‚e P. Clin Investig. 1993;71(8 Suppl):S60-5.
The antioxidant role of coenzyme Q. Bentinger M, Brismar K, Dallner G. Mitochondrion. 2007 Jun;7 Suppl:S41-50. Epub 2007 Mar 16.
Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol. Stocker R, Bowry VW, Frei B. Proc Natl Acad Sci U S A. 1991 Mar 1;88(5):1646-50.
The emerging role of coenzyme Q-10 in aging, neurodegeneration, cardiovascular disease, cancer and diabetes mellitus. Dhanasekaran M, Ren J. Curr Neurovasc Res. 2005 Dec;2(5):447-59.
Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation. Mohr D, Bowry VW, Stocker R. Biochim Biophys Acta. 1992 Jun 26;1126(3):247-54.
Plasma coenzyme Q10 response to oral ingestion of coenzyme Q10 formulations. Bhagavan HN, Chopra RK. Mitochondrion. 2007 Jun;7 Suppl:S78-88.
Age-related changes in the lipid compositions of rat and human tissues. Kal‚n A, Appelkvist EL, Dallner G. Lipids. 1989 Jul;24(7):579-84.
Coenzyme Q10 in the human retina. Qu J, Kaufman Y, Washington I. Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1814-8.
Coenzyme Q in cardiovascular disease. Singh RB, Niaz MA, Rastogi V, Rastogi SS. J Assoc Physicians India. 1998 Mar;46(3):299-306.
Perspectives on therapy of cardiovascular diseases with coenzyme Q10 (ubiquinone). Mortensen SA. Clin Investig. 1993;71(8 Suppl):S116-23.
Effects of coenzyme Q10 administration on pulmonary function and exercise performance in patients with chronic lung diseases. Fujimoto S, Kurihara N, Hirata K, Takeda T. Clin Investig. 1993;71(8 Suppl):S162-6.
A possible role of coenzyme Q10 in the etiology and treatment of Parkinson's disease. Shults CW, Haas RH, Beal MF. Biofactors. 1999;9(2-4):267-72.
Low plasma coenzyme Q10 levels as an independent prognostic factor for melanoma progression. Rusciani L, Proietti I, Rusciani A, Paradisi A, Sbordoni G, Alfano C, Panunzi S, De Gaetano A, Lippa S. J Am Acad Dermatol. 2006 Feb;54(2):234-41.
Study of CoQ10-enzymes in gingiva from patients with periodontal disease and evidence for a deficiency of coenzyme Q10. Nakamura R, Littarru GP, Folkers K, Wilkinson EG. Proc Natl Acad Sci U S A. 1974 Apr;71(4):1456-60.
Decreased levels of coenzyme Q(10) in patients with bronchial asthma. Gazdˇk F, Gvozdj kov A, N dvornˇkov R, Repick L, Jahnov E, Kucharsk J, Pij k MR, Gazdˇkov K. Allergy. 2002 Sep;57(9):811-4.
Does coenzyme Q10 play a role in opposing oxidative stress in patients with age-related macular degeneration? Blasi MA, Bovina C, Carella G, Genova ML, Jansen AM, Lenaz G, Brancato R. Ophthalmologica. 2001 Jan-Feb;215(1):51-4.
Serum coenzyme Q10 levels in thyroid disorders. Ogura F, Morii H, Ohno M, Ueno T, Kitabatake S, Hamada N, Ito K. Horm Metab Res. 1980 Oct;12(10):537-40.
Biochemical deficiencies of coenzyme Q10 in HIV-infection and exploratory treatment. Folkers K, Langsjoen P, Nara Y, Muratsu K, Komorowski J, Richardson PC, Smith TH. Biochem Biophys Res Commun. 1988 Jun 16;153(2):888-96.
Human CoQ10 deficiencies. Quinzii CM, L˘pez LC, Naini A, DiMauro S, Hirano M. Biofactors. 2008;32(1-4):113-8.
Plasma ubiquinol-10 as a marker for disease: is the assay worthwhile? Kontush A, Schippling S, Spranger T, Beisiegel U. Biofactors. 1999;9(2-4):225-9.
Evidence of plasma CoQ10-lowering effect by HMG-CoA reductase inhibitors: a double-blind, placebo-controlled study. Ghirlanda G, Oradei A, Manto A, Lippa S, Uccioli L, Caputo S, Greco AV, Littarru GP. J Clin Pharmacol. 1993 Mar;33(3):226-9.
Coenzyme Q10 and cardiovascular disease: a review. Sarter B. J Cardiovasc Nurs. 2002 Jul;16(4):9-20.
Supplemental ubiquinol in patients with advanced congestive heart failure. Langsjoen PH, Langsjoen AM. Biofactors. 2008;32(1-4):119-28.
Relative bioavailability comparison of different coenzyme Q10 formulations with a novel delivery system. Liu ZX, Artmann C. Altern Ther Health Med. 2009 Mar-Apr;15(2):42-6.
11/4/2013 Q-Avail CoQ10 VS 100mg 60 Gels by Design for Health 5
Reviewed by louise toole from Houston.
Replaced a competitors product with this one. I am happy with the product. My husband and I both take 200 mg a day. I used to take statins and wanted to replace my CoQ10. Now I take for maintenance. CoQ10 is also supposed to help with blood pressure. I no longer need BP medication and want to maintain that.
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