EPA/DHA

• Promotes a healthy cardiovascular system
• Inhibits platelet aggregation and promotes improved circulation
• Lowers serum triglycerides
• Aides in normalizing heart rhythm
• Suppresses cancer cell proliferation and promotes cancer cell apoptosis
• Suppresses cancer cell metastasis
• Important nutritional factor for normal neurodevelopment, visual acuity and behavior
• Encourages normal brain development and cognitive function
• Enhances a healthy balance of Dopamine and serotonin
• Low levels of EPA/DHA may be predictive of impulsive behavior
• Encourages normal insulin action
• Promotes normal glucose metabolism
• Reduces proinflammatory eicosanoids , cytokines, interleukin 1b, and tumor necrosis factor

Serving size: 1 Softgel Capsules
Number of servings per container: 90

Amounts per serving

• Calories.......10
• Calories from Fat.......10
• Total Fat.......1 mg.
• Saturated Fat.......0 mg.
• Cholesterol.......5 mg.
• Fish oil.......1000 mg.
• Eicosapentaenoic Acid.......180 mg.
• Docosahexaenoic Acid.......120 mg.

Suggested Dose: Take 1-2 capsules three times per day or as directed by your health care professional.

Read Customer questions and answers about Fish Oils in our FAQ.

Fish oils and their omega 3 fatty acids, eicosapentaenoic and docosahexaenoic acid (EPA/DHA), have been shown to have remarkable health promoting properties. EPA and DHA are so important that if deficiencies occur during pregnancy fetal neurodevelopment can be affected adversely. After a child?s birth omega 3 fatty acids remain important in postnatal neurodevelopment.
EPA/DHA?

Fish oils have benefits on the cardiovascular system such as reduction of platelet aggregation thus reducing the risk of thrombotic events possible triggers cerebral vascular accidents or myocardial infarctions. Through their triglyceride lowering effect, they assist in the maintenance of a healthy endothelial vascular lining and a reduction of coronary heart disease. While saturated fats have been shown to worsen coronary arrhythmias, tuna oil (omega 3 fish oil) significantly reduced the incidence and severity of arrhythmias.

Studies have indicated that omega 6 fatty acids can act as stimulators of the development and progression of several human cancers. Omega 3 fatty acids however, have been shown to inhibit these same processes. EPA appears to inhibit cancer cell proliferation, while DHA appears to enhance cancer cell apoptosis (programmed cell death). Currently the most favorable ration of omega 3 fatty to omega 6 fatty acids in the diet is 1.8 ? 1.9/1.0. Consume about twice the amount of omega 3 fatty acids to omega 6 fatty acids.

The human brain concentrates arachidonic fatty acids (AA) and DHA rapidly during the third trimester and early postnatal period during times of rapid brain growth. Deficiencies of DHA negatively impact visual acuity, neurodevelopment and behavior. Impulsive behavior has been linked to low levels of omega 3 fatty acids and well as the severity of depression.

The effect of fish oil on lipids should be evaluated in diabetics. Animal studies have shown that fish oil enhances insulin production, activity, receptor responsiveness and glucose uptake. Fish oil enhances blood sugar regulation.

Through its anti-inflammatory effects, fish oil has been shown to be beneficial in the treatment of rheumatoid arthritis, psoriasis, dysmenorrhea, multiple sclerosis and acute respiratory distress syndrome.

Fish and fish oil products can be a source of toxins such as mercury, dioxin, PCBs, etc. Good manufacturing standards are essential for safety.

1. Monograph: Fish Oil. Alternative Med Rev. 2000; 6(6): 576- 580.
2. Nikkila M. Influence of fish oil on blood lipids in coronary artery disease. Eur J Clin Nutr. 1991; Apr;45(4):209-213.
3. Fish oil protects against colon cancer. Amer J of Physiology-Cell Physiology. 2001; 280(5): C1066-C1075.
4. Dietary fatty acids effect on cardiovascular syndrome. J of Nutr Biochem. 2001; 12(4): 207-212.
5. Singer, P. Influence on serum lipids, lipoproteins and blood pressure of mackerel and herring diet in individuals with type 4 and 5 hyperlipidemia. Athero. 1985; 56(1):111-118.
6. Ariza-Ariza R, Mestanza-Peralta M, Cardiel MH. Omega-3 fatty acid in rheumatoid arthritis: an overview. Semin Arthritis Rheum. 1998; 27:366-370.
7. Curtis CL, Hughes CE, Flannery CR, et al. n-3 Fatty acids specifically modulate catabolic factors involved in articular cartilage degradation. J Biol Chem. 2000;275:721-724.
8. McManus RM, Jumpson J, Finegood DT, et al. A comparison of the effects of n-3 fatty acids from linseed oil and fish oil in well-controlled type II diabetes. Diabetes Care. 1996;9:463-467.
9. Stoll AL, Severus WE, Freeman MP, et al. Omega 3 fatty acids in bipolar disorder. Arch Gen Psychiatry. 1999; 56:407-412.
10. McLennan PL, Abeywardena MY, Charnock JS. Dietary fish oil prevents ventricular fibrillation following coronary artery occlusion and reperfusion. Am Heart J. 1988;116:709-717.
11. Galli V, Sarchielli P, Trequattrini A, et al. Cytokine secretion and eicosanoid production in the peripheral blood mononuclear cells of MS individuals undergoing dietary supplementation with n-3 polyunsaturated fatty acids. J Neuroimmunol. 1995;56:143-153.
12. Holman RT. The slow discovery of the importance of omega 3 essential fatty acids in human health. J Nutr. 1998;128:427S-433S.
13. Wainwright P. Nutritional and behavior: the role of n-3 fatty acids in cognitive function. Br J Nutr. 2000;83:337-339.
14. Lai PB, Ross JA, Fearon KC, et al. Cell cycle arrest and induction of apoptosis in pancreatic cancer cells exposed to eicosapentaenoic acid in vitro. Br J Cancer. 1996;74:1375-1383.