Supports mitochondrial fatty acid metabolism for high energy and overall vitality
Possible immune system benefits
L-Carnitine occurs naturally in animal products (esp. beef) with smaller amounts
in dairy, fish and chicken and in very small amounts in avocado and some fermented
soy products such as tempeh. Methionine and lysine serve as precursors to the
synthesis of L-Carnitine. High stress levels, parenteral nutrition individuals
and elderly individuals may not be able to synthesize sufficient quantities
of L-Carnitine. Under these circumstances L-Carnitine is considered a conditionally
essential nutrient and supplementation may be required. Children at 21/2 years
of age synthesize L-Carnitine at about 30% the adult rate. Full capacity does
not occur until age 15.
L-Carnitine has cardioprotective activity, triglyceride lowering and HDL raising
benefits. L-Carnitine may protect neurological protective properties.
Serving Size: 1 veggie capsule Number of servings per container: 60
Suggested Dose: As a dietary supplement, take 1-2 capsules daily between meals or as directed by your health care practitioner.
Read Customer questions and answers about Weight Loss in our FAQ.
All body tissues, except for the brain metabolize long-chain fatty acids for energy production. L-Carnitine transports long-chain fatty acids into the mitochondria where they are oxidized (metabolized) and enhance the mitochondrial production of adenosine triphosphate (ATP). Enhancing ATP production improves the metabolic efficiency in the tissues involved.
Walking capacity is significantly improved for individuals with lower leg cramping due to circulatory vasospasm. Skeletal muscle function and metabolic efficiency is enhanced with L-Carnitine supplementation.
Approximately 40% of those with nutrient deficiency induced muscle disease respond favorably to L-Carnitine therapy with enhanced muscle strength and reduced muscle breakdown proteins in the urine (myoglobinuria).
The liver and kidney are involved in of L-Carnitine synthesis. Those with liver disease or chronic kidney disease may have impaired L-Carnitine synthesis and suffer from L-Carnitine deficiencies in skeletal and heart muscle tissues.
L-Carnitine has been observed to lower inflammatory cytokines such as tumor necrosis factor. It also was shown to increase lymphocyte proliferation in response to mitogen exposure.
References:
PDR for Nutritional Supplements, 1st Ed. Medical Economics/Thomson Healthcare. 2001.
Bohmer T, Rynding A, Solberg HE. Carnitine levels in human serum and disease. Clin Chim Acta. 57:55-61, 1974.
Borum PR. Carnitine. Ann Rev Nutr. 3:233-259, 1983.
Brevetti G, Chiarello M, Ferulano G, et al. Increases in walking distance in individuals with peripheral vascular disease: a double-blind, cross-over study. Circul. 77:767-773, 1988.
Sachan DS, Rhew TH, Ruark RA. Ameliorating effects of carnitine on alcohol-induced fatty liver. Am J Clin Nutr. 39:738-744, 1984.
Rebouche CJ, Engel AG. Carnitine metabolism and function in humans. Ann Rev Nutr. 6:41-68, 1986.
Levocarnitine. Physician’s Desk Reference. 54th ed. Montvale, NJ; Medical Economics Company. 2957-2959, 2000.
Pola P, et al. Statistical evaluation of long term L-Carnitine therapy in hyperlipoproteinemias. Drugs Exptl Clin Res. 9:925-934, 1983.
Davini P, et al. Controlled study on L-Carnitine therapeutic efficacy in most MI individuals. Drugs Exptl Clin Res. 18:355-365, 1992.
Need Assistance? Click here to Contact Us. We can help suggest the best product for your needs!
Nutrition Consultations with Julie Haugen, MS,RD,LN/D