MicroCelle Vega CLA by Pharmax 

CLA has been demonstrated to show considerable anti-tumorogenic activity in animals. Thus, it now appears that higher levels of CLA in tissues directly correlate with lower incidence of breast cancer (Ip et al., 1999). Similar results have been demonstrated in earlier publications and it also appears that CLA may have positive effects on colon, prostate and skin cancers, as well as breast cancer.

Immune stimulation:
CLA has been shown in a number of studies to stimulate the cell-mediated immune system by enhancing activity of phagocytes and cytotoxic T-cells (Wong et al., 1997).

Anti-inflammatory activity:
CLA has been shown to substitute in cell membranes for arachidonic acid, which is the precursor to the pro-inflammatory family of eicosanoids. Although more research is required, it does appear that CLA may operate in a similar way to omega-3 fatty acids in reducing symptomology in many chronic inflammatory conditions.

The mechanism of action of CLA:
The mechanism of action for the above three physiological effects is still being elucidated finally, but the following are all contributing elements:

CLA is a potent antioxidant, neutralizing free radicals and not being involved in chain reaction peroxidation of fatty acids.
CLA substitutes into cell membranes as replacement of arachidonic acid, which releases pro-inflammatory and ultimately pro-carcinogenic eicosanoids.

CLA has been demonstrated to be directly cytotoxic to cancerous cells.

Anabolic stimulation:
Recent research has found that CLA appears to directly effect the energy metabolism of fat. It has been shown to increase oxidation or ‘burning’ of dietary fats for energy by inhibiting the deposition of fat into adipose tissue by inhibiting the enzyme lipoprotein lipase.

Similarly, it appears to enhance the release of stored fat into this energy cycle by increasing the concentration of the enzyme hormone-sensitive lipase. The cumulative effect of this is that an increase in dietary CLA appears to directly increase the metabolism of fat in the body.
CLA has become deficient in the diet as our eating habits have changed. There is now very good and accumulating evidence that the supplementation of CLA back into the diet will have significant beneficial effects on health and disease prevention.