Mitochondrial NRG

A formulary blend of nutrients, nutraceuticals, botanicals, and Krebs cycle intermediates designed to support efficient mitochondrial metabolism and energy (ATP) production.

Mitochondrial dysfunction, with its associated ATP deficiency, is related to a host of diseases, including degenerative neurological disorders, cardiovascular disease, obesity, and diabetes (reduced mitochondrial production has been demonstrated in metabolic syndrome). Mitochondria, appropriately nicknamed "the powerhouse of the cell," deteriorate with age due to ongoing exposure to free radicals, which accelerate the destruction of cellular components. As the mitochondrial function declines the cells become starved for energy and damaged, causing them to function less efficiently.

Conversely, the benefits of increased mitochondrial production and ATP availability are many, including reduced oxidative stress and agerelated deterioration as well as improved metabolic function, energy level, exercise performance, body composition, cognitive function, and lifespan (shown in animal models).

Mitochondrial NRG may be helpful for*:

• Fatigue/Chronic Fatigue Syndrome (CFS)
• Fibromyalgia (FMS)
• Exercise intolerance
• Improved athletic performance
• Post-exercise muscle soreness
• Efficient fat burning
• Healthy weight loss
• Poor cognitive (brain) function
• Those wishing to improve overall cellular and tissue vitality and health.
• Mitochondrial genetic mutations, either inborn or acquired during aging or due to excessive exercise (such as mitochondrial myopathy)

Serving Size: 4 Capsules
Servings Per Container: 30

Active Ingredients:

• Vitamin B1 (as Thiamine HCI) 50 mg
• Vitamin B2 (as Riboflavin-5-Phosphate) 10 mg
• Vitamin B3 (as Niacinamide) 5 mg
• Vitamin B6 (as Pyridoxal-5-Phosphate) 5 mg
• Vitamin B12 (as Methylcobalamin) 2000 mcg
• Magnesium (as Creatine MagnaPower Magnesium Creatine Chelate) 100 mg
• Manganese (TRAACS Manganese Glycinate Chelate) 500 mcg
• Creatine (as Creatine MagnaPower Magnesium Creatine Chelate) 550 mg
• L-Carnitine (as Fumarate) 200 mg, Fumaric Acid (from L-Carnitine Fumarate) 150 mg
• D-Ribose 100 mg
• Malic Acid 100 mg
• Succinic Acid Natural Coenzyme Q10 (Ubiquinone)** 100 mg
• Alpha Lipoic Acid 100 mg
• Trans-Resveratrol (from 200 mg Polygonum cuspidatum, root) 100 mg
• Curcumin C3 Complex 100 mg (Curcuma longa) (root & rhizomes) (containing three curcuminoids: curcumin, (bisdemethoxy curcumin, demethoxy curcumin) [standardized to contain 95% curcuminoids]
• Pantethine 50 mg

Inactive Ingredients: Microcrystalline cellulose, vegetable stearate, silicon dioxide.

Recommended Dosage:
As a dietary supplement, take two capsules two times daily with meals or as directed by your health care practitioner.

This product does not contain: wheat, yeast, soy, gluten, eggs, dairy, corn, artificial colors, flavors, sugars, or preservatives.

Mitochondrial NRG is a formulary blend of nutrients, nutraceuticals, botanicals, and Krebs cycle intermediates designed to support efficient mitochondrial metabolism and energy (ATP) production for increased vitality.

Mitochondrial NRG may be indicated for those individuals suffering with debilitating fatigue, including those diagnosed with chronic fatigue syndrome (CFS) and fibromyalgia (FMS), those wanting to increase energy output for improved athletic performance, and anyone wishing to improve overall cellular and tissue vitality and health.

It has been well established in the scientific medical literature that mitochondrial dysfunction, with its associated ATP deficiency, is related to a host of diseases, including degenerative neurological disorders (i.e., Alzheimers, Parkinsons, multiple sclerosis, amyotrophic lateral sclerosis), cardiovascular disease (i.e., heart attack, stroke, peripheral vascular disease), obesity, and diabetes (reduced mitochondrial biogenesis has been demonstrated in metabolic syndrome). Mitochondria deteriorate with age due to ongoing exposure to free radicals, which accelerate the destruction of cellular components. As the mitochondrial function declines the cells become starved for energy and damaged, causing them to function less efficiently. Many investigators suspect that caloric restriction slows aging primarily by lowering free radical production in mitochondria. Conversely, the benefits of increased mitochondrial biogenesis and ATP availability are many, including the reduction of oxidative stress and agerelated deterioration as well as improvements in metabolic function, energy level, exercise performance, body composition, cognitive function, and lifespan (shown in animal models).

Mitochondrial NRG contains nutrients known to aid in factors in mitochondrial energy production, including:

• CoQ10 rate-limiting nutritional factor in the electron transport chain (using the same patented water soluble VESIsorb technology as in our Q-Avail Nano softgels and powder, to insure optimal bioavailability)
• Alpha Lipoic Acid - cofactor in multi-enzyme complexes that catalyzes oxidative decarboxylation of alpha-keto acids such as the pyruvate dehydrogenase complex
• Pantethine - necessary to shuttle fats from the blood stream across the cellular membrane for cell entry
• L-Carnitine - necessary to shuttle those same fats across the mitochondrial membranes for burning
• B Vitamins, Magnesium and Manganese - required as Krebs cycle enzyme cofactors
• Ribose - a nucleotide repleter and direct cellular energy source
• Malic, Fumaric, and Succinic Acids - for refilling of key Krebs cycle intermediates
• Creatine - to support additional energy production (using Albions patented Creatine MagnaPower, which supplies creatine and magnesium together, both needed for healthy mitochondria)
• Resveratrol and Curcumin - botanicals shown to induce the production of additional mitochondria (mitochondrial biogenesis) through SIRT1 gene signaling and PGC-1-alpha induction. This resveratrol is in the well-absorbed trans form, the form believed to be responsible for activating the SIRT1 gene, which when turned on slows the aging process.

References:

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