L-Tyrosine
Tyrosine is the precursor amino acid from which the body makes Dopamine (with vitamin B6 as cofactor), which is then converted to Nor-epinephrine (with vitamin C as cofactor ) and then to Epinephrine (with SAMe as cofactor). Tyrosine competes for uptake with other large neutral amino acids, so in order to maximize absorption from the supplemented Tyrosine into various tissues (such as brain, adrenals, nerves), it should be taken on an empty stomach, or two hours away from a protein containing meal.
Research Review on Tyrosine:
Research shows that supplementation with Tyrosine in the range of 30-150 mg/kg body weight may provide the following benefits:
- Compensates for the age related decline in Tyrosine metabolism [1]
- Supports fat loss regimens as follows:
- may reduce appetite[20, 21]
- maintains NE (Norepinephrine) production which stimulates fat release from the fat cells [22, 25]
- Supports the brain Dopamine/ Norepinephrine production, thus providing support for:
- cognitive performance (memory and learning) and uplifted mood4, [17]
- mood disorders associated with oral contraceptive use [21]
- anti-depressant therapies whether natural or pharmacologica[l8]
- maintenance of an alert state in spite of inadequate sleep [7]
- therapies for Dopamine related addictions (cocaine, amphetamine, smoking) [24], Phenylketonuria [13], Parkinson's[23] and Alzheimer's[26].
- therapies for Chronic Fatigue Syndrome[27]
- Supports the Dopamine/Norepineprine/ Epinephrine production by the adrenal gland and consequently:
- compensates for adrenaline depletion states such as excessive psychological or physical stress and dieting [11, 18]
- prevents excessive rises in cortisol levels [12]
- Improves stamina for exercise by providing the precursor to E/NE release from nerve endings[28]
- Precursor to Thyroid hormone [15]
- Precursor to Melanin, which is protective against UV radiation [16]
GABA
Gamma-Amino Butyric Acid (GABA) is the main calming neurotransmitter in the body. GABA is both an amino acid and a neurotransmitter naturally found in the body. When the brain has a lack of GABA, several disorders may develop including anxiety, mood swings, insomnia, and depression. GABA is an effective and safe nutritional tranquilizer that some people need to control seizures or rise above anxious or depressive feelings. Exposure to estrogens, free radicals, salicylates, or food additives can affect our internal supply of GABA. A low-protein diet can also hinder production, as can an insufficient amount of zinc or vitamin B6, both of which help the body to make the nutrient.
L-Glutamine
Glutamine increases production of glutathione, the main antioxidant of the body. This in turn boosts immune function, protects all tissues from damage, and detoxifies harmful substances. Glutamine is also an important precursor for neurotransmitter substances in the brain, and supports brain wellness and mental energy. When 12 grams (four teaspoons) was given to alcoholics, glutamine eliminated alcohol cravings in 75% of those studied
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