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OmegAvail Synergy w/Lipase Softgels by Designs for Health (DFH)

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As of August 21, 2013- This item has been discontinued. Please see below for our nutritionist's suggested alternative.
   PLEASE NOTE: The following is the suggested alternative replacement for the discontinued product,
"OmegAvail Synergy w/Lipase Softgels by Designs for Health (DFH)


Omegavail Synergy w/Lipase

OmegAvail Synergy 
This unique omega 3-6-9 formula contains a blend of wild deep-sea sourced fish oils containing the omega-3 fats (EPA/DHA) in theTruTG  form, the most important omega-6 fat, GLA, from borage oil, and the omega 9 fat oleic acid from certified virgin organic macadamia nut oil.

EPA helps keep GLA metabolism in an anti-inflammatory mode.  In addition, docosahexaenoic acid (DHA) plays as many important roles in human health as EPA, with an added benefit to brain function.

The TruTG Advantage
OmegAvail Synergy still carries our TruTG seal, your assurance that the fish oils are in their natural triglyceride form and are of unmatched TG potency. Fish oils in the TG (triglyceride) form are as they occur in nature. Fish oil blends and concentrates bearing the TruTG seal are 90% to 100% triglyceride (TG) bound omega-3 oils –40%-50% higher than the industry standard for TG fish oil concentrate products!

Why the addition of lipase?
We have added lipase as a digestive aid. Lipase is an enzyme needed for breaking down lipids (fats). Lipase is primarily produced in the pancreas but is also produced in the mouth and stomach.[12]

While most healthy individuals produce sufficient amounts of pancreatic lipase, everyone can benefit from its inclusion as it relates to better digestion of fish oils. This is supported by studies that address:

  • The importance of lipase for the efficient digestion of dietary fats[3]
  • The need for lipase for those with digestive disorders that lead to pancreatic enzyme insufficiency[2
  • Why more lipase may be needed beyond normal production in the pancreas[4]

OBSOLETE Serving Size: 2 softgels
Servings Per Container: 90

Amount per Serving:
  • Calories 20
  • Calories from Fat 20
  • Total Fat 2 g
  • Cholesterol less than 5 mg
  • Omega 3 Fatty Acids:
  • EPA (Eicosapentaenoic Acid) 270 mg
  • DHA (Docosahexaenoic Acid) 180 mg
  • Omega 6 Fatty Acids:
  • GLA (Gamma Linolenic Acid from borage oil) 160mg
  • Omega 9 Fatty Acids:
  • Oleic Acid (from virgin organic macadamia nut oil) 400mg

Other Ingredients: Natural lemon flavor, lipase, mixed tocopherols; bovine gelatin, glycerine, water, annatto as natural color (softgel ingredients).

Contains fish (anchovy, sardines, mackerel or tuna oil) and tree nuts (macadamia nuts).

Recommended Use: 
As a dietary supplement, take two softgels daily with meals or as directed by your health care practitioner.

NOTICE: Color, size or shape may appear different between lots.

WARNING: Consult with your health care practitioner before use if you are taking blood thinning medication or are planning to have surgery.


Read customer questions and answers about fish oils on our blog.

OmegAvail Synergy has gone through an extensive purification process and is verified by third party testing to be free of pesticides, PCBs, dioxin and heavy metals, including mercury.

OmegAvail Synergy delivers four beneficial fatty acids in one softgel: EPA and DHA from fish oil, GLA from borage oil, and ALA from flax seed oil. OmegAvail Synergy includes TruTG fish oil which contains a minimum 90% natural TG (triglyceride) bound omega 3 oil.

The TruTG Advantage

Fish oil is considered by many if not the majority of nutritionally focused health care practitioners to be the single most important dietary supplement. In all probability, no other nutritional product has as much and varied research demonstrating its many health benefits.

Designs for Health has consistently embraced the Paleolithic nutritional philosophy upon which it was founded. As such, we are excited to announce our TruTG branded fish oil products which are guaranteed to contain 90 to 100% triglyceride-bound EPA and DHA fats. Both EPA and DHA are found naturally in fish in this triglyceride form.

The Form Nature Intended

Only Designs for Health fish oil products carry the TruTG seal your assurance that our fish oils are delivered in the form found in nature, consistent with Paleolithic nutritional philosophy, and are of unmatched TG potency. Fish oil blends and concentrates bearing the TruTG seal are 90 to 100% triglyceride (TG) bound omega-3 fish oils, which are 40%-50% higher than industry standard for TG fish oil concentrate products!

Converting Ethyl Esters to Triglycerides - Why DFH Chose a Path Less Followed

The vast majority of fish oil concentrate products available on the market today are Ethyl Esters. Not surprisingly, the reason is cost; an additional step is required to convert EEs back into their natural TG state. This added process removes the ethanol backbone and re-esterifies the omega-3 fatty acids to a glycerol backbone. Interestingly, most of the companies that choose to take this extra step and expense convert just 60 - 65% of the oil to TG leaving a mixture of EE, and mono and diglyceride oil in the remainder.

At Designs for Health, we have always placed quality, efficacy and safety above cost. This is precisely why we convert to TG the maximum amount possible, between 90% and 100%. TruTG defines this process, resulting in the highest expense, but also resulting in a finished product with the highest stability, bioavailability, and that closest to what is found in nature.

Superior Absorption and Biovailability

Numerous studies have assessed the absorption and bioavailability of EE fish oils by measuring the amount of EPA and DHA in blood plasma after ingestion of fatty acids as either TGs or EEs. Although a few studies have found the absorption rate to be similar between the two types of oils, overall evidence suggests that TG fish oils are better absorbed in comparison to EEs. One of the causative factors for the poor bioavailability of EE fish oil is a much greater resistance to digestive enzymes. During the digestive process, pancreatic lipase enzymes hydrolyze (cleave) the oils to liberate the fatty acids, and EE fish oil is much more resistant to this enzymatic process than the natural TG form.

A recent study assessed the specificity of 5 lipases towards EPA and DHA in TG and EE forms of fish oil. All of the investigated lipases hydrolyzed EPA and DHA more easily from a TG than from an EE fish oil substrate. It follows that EPA and DHA hydrolysis would be further compromised in individuals suffering from a digestive disorder, such as pancreatic insufficiency. EE fish oils should be avoided in such populations, as they would likely cause malabsorption of EPA and DHA.

A review of the existing literature provides evidence suggesting that omega-3 fatty acids in the natural TG form are more efficiently digested and significantly better incorporated into plasma lipids when compared to the EE form.

More Stable, Less Prone to Oxidation

Omega-3 fish oils in the form of EEs are much less stable than those in the natural TG form, making them more prone to oxidation. The oxidation kinetics of DHA as an EE or as a TG were assessed by measuring the concentration of oxygen found in the head space of a reaction vessel with both TG and EE forms3. The EE form of DHA was more reactive, and quickly oxidized, demonstrating that EE fish oils are far less stable and more readily produce harmful oxidation by-products3. In addition, the stability of DHA containing oil in phospholipid, triacylglycerol and the EE form has been assessed4. After a 10-week oxidation period, the EE DHA oil decayed 33% more rapidly than other forms4. In a separate study, monoglycerides were shown to be more readily oxidized when compared to triglycerides.

This suggests that individuals with health conditions associated with excessive oxidative stress should ideally consume only a 90+% TG form of fish oil.

1. Omega-3 fatty acids: the science and the beliefs. Ginsberg A, Stahl Z, Leventhal A. Harefuah. 2009 Feb;148(2):114-20, 138.
2. Lipolysis of menhaden oil triacylglycerols and the correŠsponding fatty acid alkyl esters by pancreatic lipase in vitro: a reexamination. Yang LY, Kuksis A, Myher JJ. J Lipid Res. 1990 Jan;31(1):137- 47.
3. Autoxidation kinetic analysis of docosahexaenoic acid ethyl ester and docosahexaenoic triglyceride with oxygen sensor. Yoshii H, Furuta T, Siga H, Moriyama S, Baba T, Maruyama K, Misawa Y, Hata N, Linko P. Biosci Biotechnol Biochem. 2002 Apr;66(4):749-53.
4. Oxidative stability of docosahexaenoic acid-containing oils in the form of phospholipids, triacylglycerols, and ethyl esters. Song JH, Inoue Y, Miyazawa T. Biosci Biotechnol Biochem. 1997 Dec;61(12):2085-8.
5. Oxidation of monoglyceride, diglyceride, and triglyceride monolayers by aqueous potassium per manganate solution. Singh C. P. ; Shah D. O.
6. [Comparative bioavailability of eicosapentaenoic acid and docasahexaenoic acid from triglycerides, free fatty acids and ethyl esters in volunteers] Beckermann B, Beneke M, Seitz I. Arzneimittelforsc hung. 1990 Jun;40(6):700-4. German.
7. Human absorption of fish oil fatty acids as triacylglycerols, free acids, or ethyl esters. Lawson LD, Hughes BG. Biochem Biophys Res Commun. 1988 Apr 15;152(1):328-35.
8. Enteral absorption in man of eicosapentaenoic acid in different chemical forms. el Boustani S, Colette C, Monnier L, Descomps B, Crastes de Paulet A, Mendy F. Lipids. 1987 Oct;22(10):711-
9. Dietary intake of fish vs. formulations leads to higher plasma concentrations of n-3 fatty acids. Visioli F, Risé P, Barassi MC, Marangoni F, Galli C. Lipids. 2003 Apr;38(4):415-8.
10. Effect of supplementation with docosahexaenoic acid ethyl ester and sn-2 docosahexaenyl monoa cylglyceride on plasma and erythrocyte fatty acids in rats. Valenzuela A, Valenzuela V, Sanhueza J, Nieto S. Ann Nutr Metab. 2005 Jan-Feb;49(1):49-53. Epub 2005 Feb 25.
11. Digestion and lymphatic transport of eicosapentaenoic and docosahexaenoic acids given in the form of triacylglycerol, free acid and ethyl ester in rats. Ikeda I, Sasaki E, Yasunami H, Nomiyama S, Nakayama M, Sugano M, Imaizumi K, Yazawa K. Biochim Biophys Acta. 1995 Dec 7;1259(3):297-304.
12.  S.D.Kristensen, E.B. Schmidt, R. DeCaterina, S. Endres n-3 Fatty Acids: Prevention and Treatment in Vascular Disease; Chapter 20. Bioavailability of n-3 Fatty Acid Formulations Bi & Gi Publishers, Verona Springer Verlag, London 1995

Manufacturer: DFH

Customer Reviews
Average Rating on 12 Reviews
(05 stars in 12 rating(s))
4 star rating Omega-3 7/9/2013 OmegAvail Synergy w/Lipase Softgels by Designs for Health (DFH)4
Reviewed by TFordJ from Greater Washington, DC Area.
Using in combo with Probiotics and Zinc as recommended by this site for adult acne management. Don't know how this specific supplement is helping, but I do notice a positive difference in my skin, my GI upset/regularity, and my recurrent vaginal yeast infections.

5 star rating ordering review 4/3/2012 OmegAvail Synergy w/Lipase Softgels by Designs for Health (DFH)5
Reviewed by Maria from Modesto.
Thank you for having OmegAvail Synergy w/Lipase Softgels by Designs for Health. The website was easy to get around and my order was shipped prompted. A suggestion, for a reoccurring order would be nice. Thank you Maria

5 star rating Love this 1/13/2012 OmegAvail Synergy w/Lipase Softgels by Designs for Health (DFH)5
Reviewed by Emma from St. Louis.
Thank goodness I found these fish oils! ! You can trust the products that are sold on this site! Thank You! I recommended them to my fitness friends!

5 star rating B-Brain 7/23/2011 OmegAvail Synergy w/Lipase Softgels by Designs for Health (DFH)5
Reviewed by Houston mom from Houston, Tx.
I love this product. My son has only been taking it for one month and he is much more calm. He is better with decision making and reasoning. He is also much calmer. Love it!!!

5 star rating Great product 12/18/2010 OmegAvail Synergy w/Lipase Softgels by Designs for Health (DFH)5
Reviewed by Elena from New York/ New York.
Easy to swallow, no smell, I think my skin looks better for it!

5 star rating Great product! 10/15/2010 OmegAvail Synergy w/Lipase Softgels by Designs for Health (DFH)5
Reviewed by nleep from California.
I am 9 months pregnant and swear by OmegAvail Synergy. I started taking it 2 years ago and have upped my dosage now that I am pregnant...what a difference it has made in my skin, digestion and overall health. I suffered from exzema for many years and attribute my clear skin to this supplement. Most of my pregnant friends suffer from itchy, flaky skin during pregnancy, but thankfully I have not and I'm sure it has a lot to do with OmegAvail.

5 star rating OmegAvail Synergy TG Softgels 8/24/2010 OmegAvail Synergy w/Lipase Softgels by Designs for Health (DFH)5
Reviewed by Nancy from Allen,Texas.
Great product! I have been using this product for well over a year. It has lowered my bad cholesterol, helped my skin and has the added bonus of keeping me regular.

5 star rating Getting those Omega 3s 6/16/2010 OmegAvail Synergy w/Lipase Softgels by Designs for Health (DFH)5
Reviewed by rexhouse from Granbury, TX.
This is a great supplement to get those Omega 3s without the fishy breath!

5 star rating OmegAvail Fish Oil Pills 11/24/2009 OmegAvail Synergy w/Lipase Softgels by Designs for Health (DFH)5
Reviewed by Nicole from Richmond, MI.
These pills work great. No after taste or fishy smell. You will notice a difference in your skin right away after taking. I even take these while I'm pregnant and my OB ordered a bottle.

5 star rating Omega synergy 11/19/2009 OmegAvail Synergy w/Lipase Softgels by Designs for Health (DFH)5
Reviewed by Joanna Tschudy from St. Louis.
I love the omega synergy softgels. They are effective, i love that they have four sources of fatty acid and they have no aftertaste, a definite plus!!

5 star rating OmegAvail 10/28/2009 OmegAvail Synergy w/Lipase Softgels by Designs for Health (DFH)5
Reviewed by Lindsay from Pittsburgh, PA.
I have not yet developed a taste for seafood and know my diet needs more omega-3s. I have been satisfied with this product so far and have even seen improvement in my skin condition which I wasn't expecting.

5 star rating Excellent Anti-inflammatory 9/22/2009 OmegAvail Synergy w/Lipase Softgels by Designs for Health (DFH)5
Reviewed by Sue from Buffalo, MN.
My knees used to ache most of the time until I added these wonderful EFA's (Essential Fatty Acids) to my supplement protocol - now I hardly notice they're there. I recommend these highly for anyone with arthritis. They also help keep me regular. Who knew?

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