PerioBiotic Toothpaste by Designs for Health

New toothpaste with probiotics! Fluoride-free, great tasting toothpaste for comprehensive oral health.

Available in refreshing Fennel, Spearmint and Watermelon(NEW) Flavors!

What makes PerioBiotic? unique?
PerioBiotic? Toothpaste contains Dental-Lac?, a patent pending and clinically tested functional lactobacillus dental hygiene probiotic not found in any other toothpaste. Research on Dental-Lac?, a specific Lactobacillus paracasei strain, demonstrates its ability to kill off harmful strains of oral bacteria including streptococcus mutans, a significant contributor to dental caries, tooth decay and periodontal disease. Like probiotics in the human intestinal tract, beneficial flora in the mouth are critical to maintaining an oral environment conducive to healthy teeth and gums.

And PerioBiotic? Toothpaste contains two active ingredients that have been shown in research to promote dental and oral health via their cavity-fighting abilities:

• xylitol
• calcium glycerophosphate.

What?s not in PerioBiotic? does matter...
The ingredients not found in PerioBiotic? Toothpaste, which are found in most other toothpastes include:fluoride, sodium lauryl sulfate (SLS), and saccharin. Also, this product is not harmful if swallowed as it does not contain fluoride.

Spearmint Flavour

Active Ingredients:

• Water
• calcium carbonate
• calcium glycerophosphate
• glycerin
• xylitol
• sodium bicarbonate
• spearmint oil (Mentha Viridis)
• carrageenan
• maltodextrin
• Dental-Lac?(Lactobacillus paracasei)
• potassium sorbate
• yucca powder (Y.Filamentosa)
• stevia leaf extract (Eupatorium rebaudianum)
• zinc chloride

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Fennel Flavour

Active Ingredients:

• Water
• calcium carbonate
• calcium glycerophosphate
• glycerin
• xylitol
• sodium bicarbonate
• sweet fennel oil (Foeniculum Vulgarae)
• carrageenan
• maltodextrin
• Dental-Lac?(Lactobacillus paracasei)
• potassium sorbate
• yucca powder (Y. Filamentosa)
• stevia leaf extract (Eupatorium rebaudianum)
• zinc chloride

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Watermelon Flavour

Active Ingredients:

• Water
• calcium carbonate
• calcium glycerophosphate
• glycerin
• xylitol
• sodium bicarbonate
• natural watermelon flavor
• carrageenan
• maltodextrin
• Dental-Lac?(Lactobacillus paracasei)
• potassium sorbate
• yucca powder (Y. Filamentosa)
• stevia leaf extract (Eupatorium rebaudianum)
• zinc chloride

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Suggested Use:
Apply PerioBiotic toothpaste on to a soft bristle toothbrush. Brush thoroughly after meals for at least 1 minute. Spit out the excess solution, and for maximum benefits do not rinse to allow longer contact of the natural ingredients to the teeth and gums. The remaining solution is not harmful if swallowed as it does not contain fluoride. Brush 2 to 3 times per day or as directed by your health care professional.

NOTICE: This is a natural product that may exhibit color, taste and density variations from lot to lot.

Read customer questions and answers about Gums and Teeth on our blog.

Why should we consider limiting or avoiding fluoride, SLS and saccharin?

Fluoride
The most recognized problem with the ingestion of too much fluoride is dental fluorosis. This condition is characterized by the failure of tooth enamel to crystallize properly in permanent teeth. The effects range from chalky, opaque blotching of teeth to severe, rust-colored stains, surface pitting and tooth brittleness. Fluoride consumption is also believed to contribute to the incidence of hypothyroidism.

Dr. John Yiamouyiannis examined the raw data from a large study that was conducted by the National Institute for Dental Research (NIDR). He concluded that fluoride did not appear to have any decay preventing success, as there was little difference in the DMFT values (the mean number of decayed, missing or filled teeth) for approximately 40,000 children. It did not matter whether they grew up in fluoridated, non-fluoridated or partially fluoridated communities. (Yiamouyiannis, J.A. Water Fluoridation and Tooth Decay: Results from the 1986-87 National Survey of U.S. Schoolchildren?, Fluoride, 23, 55-67, 1990).

A larger study has been conducted in New Zealand. The New Zealand National Health Service plan examines the teeth of every child in key age groups, and have found that the teeth of children in non-fluoridated cities were slightly better than those in the fluoridated cities. (Colquhoun, J. ?Child Dental Health Differences in New Zealand?, Community Healthy Services, XI 85-90, 1987).

Sodium Lauryl Sulfate
Sodium Lauryl Sulfate (SLS) is believed to contribute to canker sores.

Saccharin
In 1977, research showed bladder tumors in male rats with the ingestion of saccharin. It remains questionable as to whether this translates to humans. On a different note, saccharin belongs to a class of compounds known as sulfonamides which can cause allergic reactions in individuals who cannot tolerate sulfa drugs. Reactions can include headaches, breathing difficulties, skin eruptions, and diarrhea.

If you would like the PubMed weblinks to these research studies, please contact our nutritionist at MyNutritionist@rockwellnutrition.com

1. Lactic acid bacteria from healthy oral cavity of Thai volunteers: inhibition of oral pathogens.  Sookkhee S, Chulasiri M, Prachyabrued W.  J Appl Microbiol. 2001 Feb;90(2):172-9.PMID: 11168719 [PubMed - indexed for MEDLINE]Related citations

2. Calcium glycerophosphate and caries: a review of the literature.  Lynch RJ.  Int Dent J. 2004;54(5 Suppl 1):310-4. Review.PMID: 15509082 [PubMed - indexed for MEDLINE]Related citations

3. Cariostatic activity of calcium glycerophosphate in hamsters: topical vs dietary administration.  Pianotti RS, Ambrozaitis JD, McNamara TF.  J Dent Res. 1976 Nov-Dec;55(6):1092-6.PMID: 1069757 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

4. Xylitol in relation to the incidence of dental caries.  Scheinin A.Int Z Vitam Ernahrungsforsch Beih. 1976;15:358-67.PMID: 1066333 [PubMed - indexed for MEDLINE]Related citations

5.Xylitol pediatric topical oral syrup to prevent dental caries: a double-blind randomized clinical trial of efficacy.  Milgrom P, Ly KA, Tut OK, Mancl L, Roberts MC, Briand K, Gancio MJ.  Arch Pediatr Adolesc Med. 2009 Jul;163(7):601-7.PMID: 19581542 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

6.Xylitol and caries: the collaborative WHO oral disease preventive programme in Hungary.  Scheinin A, B n˘czy J.  Int Dent J. 1985 Mar;35(1):50-7.PMID: 3858229 [PubMed - indexed for MEDLINE]Related citations

7.Xylitol gummy bear snacks: a school-based randomized clinical trial.  Ly KA, Riedy CA, Milgrom P, Rothen M, Roberts MC, Zhou L.  BMC Oral Health. 2008 Jul 25;8:20.PMID: 18657266 [PubMed]Free PMC ArticleFree textRelated citations

8.Linear response of mutans streptococci to increasing frequency of xylitol chewing gum use: a randomized controlled trial [ISRCTN43479664]. Ly KA, Milgrom P, Roberts MC, Yamaguchi DK, Rothen M, Mueller G.  BMC Oral Health. 2006 Mar 24;6:6.PMID: 16556326 [PubMed]Free PMC ArticleFree textRelated citations

9.Thirty-nine-month xylitol chewing-gum programme in initially 8-year-old school children: a feasibility study focusing on mutans streptococci and lactobacilli.  M„kinen KK, Alanen P, Isokangas P, Isotupa K, S”derling E, M„kinen PL, Wenhui W, Weijian W, Xiaochi C, Yi W, Boxue Z.  Int Dent J. 2008 Feb;58(1):41-50.PMID: 18350853 [PubMed - indexed for MEDLINE]Related citations

10.Six-month polyol chewing-gum programme in kindergarten-age children: a feasibility study focusing on mutans streptococci and dental plaque.  M„kinen KK, Isotupa KP, M„kinen PL, S”derling E, Song KB, Nam SH, Jeong SH.  Int Dent J. 2005 Apr;55(2):81-8.PMID: 15880962 [PubMed - indexed for MEDLINE]Related citations

11.Dental plaque formation and salivary mutans streptococci in schoolchildren after use of xylitol-containing chewing gum.  Holgerson PL, Sj”str”m I, Stecksén-Blicks C, Twetman S.  Int J Paediatr Dent. 2007 Mar;17(2):79-85.PMID: 17263856 [PubMed - indexed for MEDLINE]Related citations

12.The effect of xylitol chewing gum on mutans streptococci in saliva and dental plaque.  Thaweboon S, Thaweboon B, Soo-Ampon S.  Southeast Asian J Trop Med Public Health. 2004 Dec;35(4):1024-7.PMID: 15916109 [PubMed - indexed for MEDLINE]Related citations

13.Sugar substitutes, chewing gum and dental caries--a review.  Edgar WM. Br Dent J. 1998 Jan 10;184(1):29-32. Review.PMID: 9479811 [PubMed - indexed for MEDLINE]Related citations

14.Xylitol chewing gums and caries rates: a 40-month cohort study.  M„kinen KK, Bennett CA, Hujoel PP, Isokangas PJ, Isotupa KP, Pape HR Jr, M„kinen PL.  J Dent Res. 1995 Dec;74(12):1904-13.PMID: 8600188 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

15.Stabilisation of rampant caries: polyol gums and arrest of dentine caries in two long-term cohort studies in young subjects.  M„kinen KK, M„kinen PL, Pape HR Jr, Allen P, Bennett CA, Isokangas PJ, Isotupa KP.  Int Dent J. 1995 Feb;45(1 Suppl 1):93-107.PMID: 7607749 [PubMed - indexed for MEDLINE]Related citations

16.Six months of daily high-dose xylitol in high-risk schoolchildren: a randomized clinical trial on plaque pH and salivary mutans streptococci.  Campus G, Cagetti MG, Sacco G, Solinas G, Mastroberardino S, Lingstr”m P.  Caries Res. 2009;43(6):455-61. Epub 2009 Dec 10.PMID: 20016175 [PubMed - indexed for MEDLINE]Related citations

17.Xylitol gum and maternal transmission of mutans streptococci.  Nakai Y, Shinga-Ishihara C, Kaji M, Moriya K, Murakami-Yamanaka K, Takimura M.  J Dent Res. 2010 Jan;89(1):56-60. Epub .PMID: 19948944 [PubMed - indexed for MEDLINE]Related citations

18.Antibacterial and probiotic approaches to caries management.  Adair SM, Xie Q.  Adv Dent Res. 2009;21(1):87-9. Epub 2009 Jul 29.PMID: 19717416 [PubMed - in process]Related citations

19.Towards tooth friendly soft drinks.  Kolahi J, Fazilati M, Kadivar M.  Med Hypotheses. 2009 Oct;73(4):524-5. Epub 2009 Jun 30.PMID: 19570614 [PubMed - indexed for MEDLINE]Related citations

20.Effect of xylitol and sorbitol on plaque acidogenesis.  Splieth CH, Alkilzy M, Schmitt J, Berndt C, Welk A.  Quintessence Int. 2009 Apr;40(4):279-85.PMID: 19417872 [PubMed - indexed for MEDLINE]Related citations