Permeability Complex I by Pharmax 

• Fructooligosaccharides (FOS) stimulate the microbial flora to produce butyric acid, essential for colonocyte integrity.
• L-glutamine (and aspartic acid) are primary cell fuels for enterocytes and also act as a glutathione precursor
• L-arginine supports mucosal cell growth and repairs and stimulates the mucosal production of nitric oxide by mucosal defense cells
• Vitamin C and vitamin E stimulate the mucosal immune system and assist in the repair and growth of the mucosal barrier
• N-acetyl glucosamine forms part of the glycocalyx exudates at the surface of the mucosal barrier
• Zinc stimulates the mucosal immune system
• Vitamin A is essential for correct differentiation and integrity of epithelial cells. Vitamin A deficiency causes flat, dry, keratinised epithelial cells.
• Ginger oil soothes the intestinal lining and assists in repair and normal functioning

Read Customer questions and answers about Digestive Health in our FAQ.

A permeable or ‘leaky’ mucosal lining of the gut is created when the tight junctions between individual epithelial cells (ecterocytes and colonocytes) become disengaged. This can be caused by use of antibiotics, gastrointestinal infections, poor diet or toxin overload. It is also an integral part of many gastrointestinal diseases such as inflammatory bowel disease and irritable bowel syndrome.

The presence of a permeable mucosal barrier allows antigens, toxins, allergens and living microorganisms potential access to the systemic immune system and thereafter to distant organs and tissues throughout the body.

Permeability Complex is essential to the nutritional therapy of any individual whose symptoms originate or are concentrated in the gastrointestinal tract or liver. Also Permeability Complex is clearly an essential component in any detoxification program.

Permeability Complex l should be used for a minimum of 60 days after which the maintenance level of intestinal conditioning nutrients found in Permeability Complex ll can be used.