Types: 90 caps (price shown) and 125g powder. You must login or register in order to view product options and prices for each.

Designs for Health’s Probiotic Synergy takes advantage of a new patented delivery technology. It is designed to ensure that the bacteria survive passage through the stomach to the small intestine. The polysaccharide matrix is a delivery system involving gel-forming polysaccharides that are insoluble at a low (acidic) pH like that in the stomach.

Size: 90 capsules
Each capsule provides:

• Lactobacillus acidophilus LA-5 1.68 billion
• Bifidobacterium BB-12 1.68 billion
• Streptococcus thermophilus .44 billion
• Lactobacillus delbrueckii ssp bulgaricus .20 billion

Other Ingredients: Dextrose, magnesium stearate, gelatin, titanium dioxide.

Dose suggestions: 1-3 caps per day with meals.

To counteract antibiotic side effects: 1-3 capsules at bedtime away from antibiotics. Continue for a few weeks after antibiotics are discontinued.

*Store in refrigerator or freezer for optimal shelf life of 1 year.
Product will be shipped cold.

Size: 125 grams/62.5 servings per container
Each one-half teaspoon (2 grams) provides: 20 billion total organisms

• Lactobacillus acidophilus 3.34 billion
• Lactobacillus paracasei 3.34 billion
• Lactobacillus plantarum 3.34 billion
• Bifidobacterium longum 3.34 billion
• Bifidobacterium infantis 3.34 billion
• Bifidobacterium lactis 3.34 billion

Other Ingredients: Rice Maltodextrin.

Recommended Use
As a dietary supplement, take 1/2 teaspoon (2 grams) or more per day or as directed by your health care practitioner.

STORE IN A COOL, DRY PLACE. KEEP OUT OF REACH OF CHILDREN.

Designs for Health Probiotic Synergy Powder is made from the highest quality probiotic strains available. For maximum potency and viability, refrigeration is recommended, even though these probiotics are designed to be stable at room temperature.

Read Customer questions and answers about Digestive Health in our FAQ.

When this capsule enters the stomach, it begins to dissolve in the gastric juice. The polysaccharides in the gel rehydrate and form an insoluble gel matrix. The protected bacteria move their way to the small intestine where the increased, more alkaline pH causes the probiotics to release—right where we want them. There is now no need to overstuff the capsules to account for die-off of organisms due to their typical intolerance to stomach acid. Room temperature is ideal. Keep out of extreme temperatures—especially heat.

• Infants being delivered by C-section or that are not breast fed long enough to establish a strong friendly flora for immunological health
• Pasteurization of foods and decreased consumption of fermented foods
• Increase in the use of antibiotics in our livestock
• Overuse of antibiotics in treating human infections which may not be caused by bacteria
• Over consumption of sugar and carbohydrates which promote yeast overgrowth
• Over consumption of alcohol which promotes yeast overgrowth

• Immune defense at the intestinal and systemic level
• Minimize the side effects of
• antibiotics
• Minimize allergic responses
• Prevention/alleviation of traveler's diarrhea
• Prevention/alleviation of diarrhea and constipation in infants, adults and elderly
• Inhibit growth of pathogenic organisms: bacteria, yeast, parasites
• Improve digestion of lactose
• Alleviate inflammatory bowel disease/ulcerative colitis
• Vitamin K synthesis
• Alleviate atopic dermatitis

Probiotic Synergy has Ensured Survival in Intestines:
This new improved Probiotic Synergy capsules is ideally taken with or after meals since it takes advantage of a patented technology delivery-system which ensures that acid-sensitive probiotics survive passage through the stomach and arrive safely in the alkaline intestinal tract where they can thrive and provide health benefits. This unique delivery technology is designed to ensure that the bacteria survive passage through the stomach to the small intestine. The delivery system involves gel-forming polysaccharides that are insoluble at a low (acidic) pH like that in the stomach. When this capsule enters the stomach, it begins to dissolve in the gastric juice. The polysaccharides in the gel rehydrate and form an insoluble gel matrix. The protected bacteria move their way to the small intestine where the increased, more alkaline pH causes the probiotics to release - right where we want them.

Glass Bottle
The product is also now stored in glass bottles which provide added potency protection. We chose these new glass bottles because they are best able to protect these moisture and heat sensitive live organisms from UV rays, moisture and heat. We include two desiccant packs that protect the capsules from moisture after the bottle has been opened.

Stability
This Newly Improved Probiotic formula has a two year shelf life at room temperature but refrigeration is highly recommended. There is now no need to overstuff the capsules to account for die-off of organisms due to their typical instability to stomach acid. These new capsules contain about 4 billion live active healthy bacteria.

Summary of benefits for Probiotic Synergy:
1) Advanced technology capsule forms a gel matrix to protect from stomach acid
2) Probiotic Synergy is stored and shipped cold to prevent overheating, which can lower viability.
3) It is also stored and shipped to you in a glass bottle, with two high-tech desiccant packets, providing even more protection and stability to these live probiotics.
4) Four strain formula, including the Bifidobacterium BB-12 and Lactobacillus Acidophilus LA-5, backed by human research

Research Summaries:
Four healthy adults received 1 Probiotic capsule at each meal (acid resistant capsule- 4 billion count per cap). Both strains were found in the duodenum after ingestion indicating survival through the stomach. The number of bifidobacteria in the feces increased significantly during treatment indicating adherence and colonization. (This is an indication that the strains are surviving when taken with food.) This small but promising study shows a need for further research on this subject.

When LA-5 (Lactobacillus acidophilus), BB-12 (Bifidobacterium), Streptococcus thermophilus and Lactobacillus bulgaricus were given (3.5 billion, twice a day) to 23 healthy subjects receiving an antibiotic 4 times daily for 7 days, the total number of healthy microorganisms was significantly higher in the group receiving the probiotics, and only 18% of the probiotic group was colonized with clostridium dificile compared to 41% of the placebo group. C. dificile is a cause of diarrhea.

When 23 geriatric patients were given fermented milk that contained .4-1.6 billion Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 strains, there was a significant improvement in frequency of bowel movements and diminished need for laxatives that have a negative effect on electrolyte balance.

Phagocytic activity of leukocytes and phagocytosis of E. Coli were both enhanced after administration of BB-12 fermented milk to 28 healthy adults for three weeks.

When 30 healthy adults were given fermented milk that contained BB-12 and Lactobacillus Acidophilus, and then given Salmonella typhi to mimic an enteropathogenic infection, the number of fecal bacteria increased. Serum IgA titre to Salmonella typhi was significantly higher (four fold), total serum IgA significantly increased and IgG titres remained higher longer than the control group.

54 infants in a double-blind randomized controlled trial were breast fed or fed a fermented milk formula containing Streptococcus thermophilus and BB-12. The formula with these strains induced bifidobacterium colonization at 1 month of age. The BB-12 formula was well tolerated and promoted normal growth in the infants.

Clinical symptoms of atopic dermatitis improved significantly after supplementation of BB-12 Bifidobacterium to patients on an elimination diet compared to those on the diet that received placebo.

A double-blind study was performed on 16 patients with proctocolectomy for ulcerative colitis. Those given LA-5 and BB-12 strains decreased daily stools from 5.8 to 2.8 and the number of LA-5 and BB-12 in the stools increased significantly.

Protection rate against traveler's diarrhea was 39% in 94 healthy tourists.

Email us for a list of scientific references to these studies.

Research Review

Designs for Health is once more taking advantage of the latest advancements in scientific technology. Our new Probiotic Synergy Powder has gone from 4 good but standard strains to 6 much more stable and viable strains -- carefully selected to be acid tolerant and provide excellent adherence to the gut wall. These 6 strains represent the most necessary, stable and best-researched bacteria known today. We now provide 20 billion live organisms per half teaspoon.

Probiotics maintain a healthy bacterial environment in the intestines by displacing bad bacteria, aiding digestion of food including dairy products and by combating yeast overgrowth. Beneficial bacteria also aid in the synthesis of Vitamin K and CLA and possibly the B Vitamins. Many doctors recommend Probiotics after a patient has been taking antibiotics. Daily use of Probiotic Synergy supports healthy bowel movements. Our new Probiotic Synergy Powder is much more room-temperature stable, although refrigeration is still recommended to enhance long-term viability.

Commonly Asked Questions

WHY DO SOME FORMULAS ADD FOS?
Adding FOS has a few benefits and also negatives. FOS is inherently high in moisture so will relinquish this in the capsule, leading to reduced viability of the organisms and reduced stability of the product. The lower the water activity of a diluent the better, which is why low Aw, non-GMO, rice maltodextrin is used. Although the FOS may provide a food source in the intestine, the amount added is almost insignificant as it is a macro nutrient and most intestines would have adequate food source unless the person is fasting.

WHY DID WE CHOOSE THESE STRAINS?
Designs for Health gets the probiotic strains for this unique, powdered formula from the largest, most trusted producer of dietary supplement probiotics in the United States. This allows us to take advantage of decades of technical expertise, professional know-how from world experts in microbiology, and a state-of-the-art Quality Control department that ensures both the safety and efficacy of these well-researched strains.

The probiotic strains in this formula were produced using a patented stabilization system; the end-result of a 3-year R&D program performed in the United States. So, as long as you keep this product cool or at room temperature, you can trust these probiotics to be stable and viable for 2 full years, as well as inherently acid-and bile-resistant. That means you can just stir a teaspoon of Probiotic Synergy powder in water, add them to your PaleoMeal shake, or sprinkle them into yogurt or on any cold food, and you will get the full benefits of the best researched probiotics in the world.

Lactobacillus plantarum was chosen because of its ability to produce high amounts of beneficial enzymes such as protease for aiding protein digestion.

Bifidobacterium lactis and longum have a tremendous amount of research behind them and are very hearty, stable strains. Bifidobacterium lactis will populate the lower intestine whereas the Lactobacillus plantarum will populate the upper intestine. Lactobacillus plantarum also helps lower the pH, making the environment better for the Bifidobacterium lactis.