Exchanges, refunds or returns on this item are not allowed.
Probiotic Synergy
Designs for Healths reformulated Probiotic Synergy uses the most advanced patented delivery and shelf stability technology available to ensure maximum potency and viability. This is achieved using the latest techniques designed to protect fragile probiotic organisms from harsh stomach acid and deliver the highest number of live organisms to the intestinal tract.
Designs for Healths Probiotic Synergy takes advantage of a new patented delivery technology. It is designed to ensure that the bacteria survive passage through the stomach to the small intestine. The polysaccharide matrix is a delivery system involving gel-forming polysaccharides that are insoluble at a low (acidic) pH like that in the stomach.
Summary of Benefits for Probiotic Synergy:
Advanced technology capsule forms a gel matrix to protect from stomach acid
Probiotic Synergy is stored and shipped cold to prevent overheating, which can lower viability.
It is also stored and shipped to you in a glass bottle, with two high-tech desiccant packets, providing even more protection and stability to these live probiotics.
Four strain formula, including the Bifidobacterium BB-12 and Lactobacillus Acidophilus LA-5, backed by human research
Recommended Use: As a dietary supplement, take one sphere daily with meals or as directed by your health care practitioner.
This product does not contain: wheat, yeast, soy, gluten, eggs, artificial colors, flavors, sugars, or preservatives.
Refrigeration is recommended, and Designs for Health will ensure maximum potency and shelf life. Organism potency will decrease slowly and can be accelerated through exposure to heat, humidity or direct sunlight.
Recommended Use
As a dietary supplement, take 1 teaspoon (2 grams) or more per day or as directed by your health care practitioner.
Designs for Health Probiotic Synergy Powder is made from the highest quality probiotic strains available. For maximum potency and viability, refrigeration is recommended, even though these probiotics are designed to be stable at room temperature.
Read customer questions and answers about Digestive Health on our blog.
With probiotics, its all about survival. Probiotic organisms must survive three critical barriers to be of benefit to the consumer - the manufacturing process, time on the shelf, and most importantly, survive transit through the acidic environment of the stomach. Designs for Healths new Probiotic Synergy is formulated to handle all of the above, presented in moisture-resistant BIO-tract Probiospheres® that enhance stability and the ultimate delivery of probiotic organisms to the intestinal tract.
Regular consumption of probiotics may improve diarrhea, constipation, immune response, mucin production, dysbiosis, bacterial infections, yeast overgrowth, and should be considered during or after use of antibiotics.
This translates to better resultsthrough increased levels of protected bacteria optimally released throughout the entire digestive tract.
When this capsule enters the stomach, it begins to dissolve in the gastric juice. The polysaccharides in the gel rehydrate and form an insoluble gel matrix. The protected bacteria move their way to the small intestine where the increased, more alkaline pH causes the probiotics to releaseright where we want them. There is now no need to overstuff the capsules to account for die-off of organisms due to their typical intolerance to stomach acid. Room temperature is ideal. Keep out of extreme temperaturesespecially heat.
Recommended Use: 3 capsules per day with food, if possible, since this unique capsule technology works better with food in the stomach. Take at least 3 hours away from administration of antibiotics.
Factors which increase the need for probiotics:
Infants being delivered by C-section or that are not breast fed long enough to establish a strong friendly flora for immunological health
Pasteurization of foods and decreased consumption of fermented foods
Increase in the use of antibiotics in our livestock
Overuse of antibiotics in treating human infections which may not be caused by bacteria
Over consumption of sugar and carbohydrates which promote yeast overgrowth
Over consumption of alcohol which promotes yeast overgrowth
Common Indications
Immune defense at the intestinal and systemic level
Minimize the side effects of antibiotics
Minimize allergic responses
Prevention/alleviation of traveler's diarrhea
Prevention/alleviation of diarrhea and constipation in infants, adults and elderly
Inhibit growth of pathogenic organisms: bacteria, yeast, parasites
Probiotic Synergy has Ensured Survival in Intestines: This new improved Probiotic Synergy capsules is ideally taken with or after meals since it takes advantage of a patented technology delivery-system which ensures that acid-sensitive probiotics survive passage through the stomach and arrive safely in the alkaline intestinal tract where they can thrive and provide health benefits. This unique delivery technology is designed to ensure that the bacteria survive passage through the stomach to the small intestine. The delivery system involves gel-forming polysaccharides that are insoluble at a low (acidic) pH like that in the stomach. When this capsule enters the stomach, it begins to dissolve in the gastric juice. The polysaccharides in the gel rehydrate and form an insoluble gel matrix. The protected bacteria move their way to the small intestine where the increased, more alkaline pH causes the probiotics to releaseright where we want them.
Glass Bottle The product is also now stored in glass bottles which provide added potency protection. Designs for Health chose these new glass bottles because they are best able to protect these moisture and heat sensitive live organisms from UV rays, moisture and heat. Two desiccant packs are included that protect the capsules from moisture after the bottle has been opened.
Stability This Newly Improved Probiotic formula has a two year shelf life at room temperature but refrigeration is highly recommended. There is now no need to overstuff the capsules to account for die-off of organisms due to their typical instability to stomach acid. These new capsules contain about 5 billion live active healthy bacteria.
Summary of Benefits for Probiotic Synergy:
Advanced technology capsule forms a gel matrix to protect from stomach acid
Probiotic Synergy is stored and shipped cold to prevent overheating, which can lower viability.
It is also stored and shipped to you in a glass bottle, with two high-tech desiccant packets, providing even more protection and stability to these live probiotics.
Four strain formula, including the Bifidobacterium BB-12 and Lactobacillus Acidophilus LA-5, backed by human research
Research Summaries: Four healthy adults received 1 Probiotic capsule at each meal (acid resistant capsule- 5 billion count per cap). Both strains were found in the duodenum after ingestion indicating survival through the stomach. The number of bifidobacteria in the feces increased significantly during treatment indicating adherence and colonization. (This is an indication that the strains are surviving when taken with food.) This small but promising study shows a need for further research on this subject.
When LA-5 (Lactobacillus acidophilus), BB-12 (Bifidobacterium), Streptococcus thermophilus and Lactobacillus bulgaricus were given (3.5 billion, twice a day) to 23 healthy subjects receiving an antibiotic 4 times daily for 7 days, the total number of healthy microorganisms was significantly higher in the group receiving the probiotics, and only 18% of the probiotic group was colonized with clostridium dificile compared to 41% of the placebo group. C. dificile is a cause of diarrhea.
When 23 geriatric patients were given fermented milk that contained .4-1.6 billion Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 strains, there was a significant improvement in frequency of bowel movements and diminished need for laxatives that have a negative effect on electrolyte balance.
Phagocytic activity of leukocytes and phagocytosis of E. Coli were both enhanced after administration of BB-12 fermented milk to 28 healthy adults for three weeks.
When 30 healthy adults were given fermented milk that contained BB-12 and Lactobacillus Acidophilus, and then given Salmonella typhi to mimic an enteropathogenic infection, the number of fecal bacteria increased. Serum IgA titre to Salmonella typhi was significantly higher (four fold), total serum IgA significantly increased and IgG titres remained higher longer than the control group.
54 infants in a double-blind randomized controlled trial were breast fed or fed a fermented milk formula containing Streptococcus thermophilus and BB-12. The formula with these strains induced bifidobacterium colonization at 1 month of age. The BB-12 formula was well tolerated and promoted normal growth in the infants.
Clinical symptoms of atopic dermatitis improved significantly after supplementation of BB-12 Bifidobacterium to patients on an elimination diet compared to those on the diet that received placebo.
A double-blind study was performed on 16 patients with proctocolectomy for ulcerative colitis. Those given LA-5 and BB-12 strains decreased daily stools from 5.8 to 2.8 and the number of LA-5 and BB-12 in the stools increased significantly.
Protection rate against traveler's diarrhea was 39% in 94 healthy tourists.
Email us for a list of scientific references to these studies.
Research Review
Designs for Health is once more taking advantage of the latest advancements in scientific technology. Designs for Healths new Probiotic Synergy Powder has gone from 4 good but standard strains to 6 much more stable and viable strainscarefully selected to be acid tolerant and provide excellent adherence to the gut wall. These 6 strains represent the most necessary, stable and best-researched bacteria known today. Designs for Health now provides 20 billion live organisms per half teaspoon.
Probiotics maintain a healthy bacterial environment in the intestines by displacing bad bacteria, aiding digestion of food including dairy products and by combating yeast overgrowth. Beneficial bacteria also aid in the synthesis of Vitamin K and CLA and possibly the B Vitamins. Many doctors recommend Probiotics after a patient has been taking antibiotics. Daily use of Probiotic Synergy supports healthy bowel movements. Designs for Healths new Probiotic Synergy Powder is much more room-temperature stable, although refrigeration is still recommended to enhance long-term viability.
Commonly Asked Questions
Why Do Some Formulas Add FOS? Adding FOS has a few benefits and also negatives. FOS is inherently high in moisture so will relinquish this in the capsule, leading to reduced viability of the organisms and reduced stability of the product. The lower the water activity of a diluent the better, which is why low Aw, non-GMO, rice maltodextrin is used. Although the FOS may provide a food source in the intestine, the amount added is almost insignificant as it is a macro nutrient and most intestines would have adequate food source unless the person is fasting.
Why Did We Choose These Strains? Designs for Health gets the probiotic strains for this unique, powdered formula from the largest, most trusted producer of dietary supplement probiotics in the United States. This allows us to take advantage of decades of technical expertise, professional know-how from world experts in microbiology, and a state-of-the-art Quality Control department that ensures both the safety and efficacy of these well-researched strains.
The probiotic strains in this formula were produced using a patented stabilization system; the end-result of a 3-year R&D program performed in the United States. So, as long as you keep this product cool or at room temperature, you can trust these probiotics to be stable and viable for 2 full years, as well as inherently acid-and bile-resistant. That means you can just stir a teaspoon of Probiotic Synergy powder in water, add them to your PaleoMeal shake, or sprinkle them into yogurt or on any cold food, and you will get the full benefits of the best researched probiotics in the world.
Lactobacillus plantarum was chosen because of its ability to produce high amounts of beneficial enzymes such as protease for aiding protein digestion.
Bifidobacterium lactis and longum have a tremendous amount of research behind them and are very hearty, stable strains. Bifidobacterium lactis will populate the lower intestine whereas the Lactobacillus plantarum will populate the upper intestine. Lactobacillus plantarum also helps lower the pH, making the environment better for the Bifidobacterium lactis.
Store In A Cool, Dry Place. Keep Out Of Reach Of Children.
Metchnikoff, lie. 1907. Prolongation of Life. William Heinemann, London.
Mercenier, A., Pavan, S., and B. Pot. 2002. Probiotics as biotherapeutic agents: present knowledge and future prospects. Current Pharmaceutical Design. 8:99-110.
Health and nutritional properties of probiotics in food including powder milk with live lactic acid bacteria. Report of a Joint FAO/WHO Expert Consultation on Evaluation of Health and Nutritional Properties of Probiotics in Food Including Powder Milk with Live Lactic Acid Bacteria. Crdoba, Argentina, 1-4 October 2001. (ftp://ftp.fao.org/es/esn/food/probio_report_en.pdf)
Scardovi, V. 1986. Genus Bifidobacterium, p. 1418-1434. In Sneath, P., Mair, N., Sharpe, M., and J.G. Holt (ed.), Bergeys manual of systematic bacteriology, vol. 2. Williams & Wilkins, Baltimore, MD.
Mitsuoka, T. 1996. Intestinal flora and human health. Asia Pacific J. Clin. Nutr. 5:2-9.
Meile, L., Ludwig, W., Rueger, U., Gut, C., Kaufmann, P., Dasen, G., Wenger, S., and M. Teuber. 1997. Bifidobacterium lactis sp. nov., a moderately oxygen tolerant species isolated from fermented milk. Syst. Appl. Microbiol. 20:57-64.
Ventura, V., and R. Zink. 2002. Rapid identification, differentiation, and proposed new taxonomic classification of Bifidobacterium lactis. Appl. Environ. Microbiol. 68(12):6429-6434.
Marteau, P., Pochart, P., Bouhnik, Y., Zidi, S., Goderel, I., and J.C. Rambaud. 1992. Survival of Lactobacillus acidophilus and Bifidobacterium sp. in the small intestine following ingestion in fermented milk. A rational basis for the use of probiotics in man. Gastroenterol. Clin. Biol. 16(1):25-28.
Bouhnik, Y., Pochart, P., Marteau, P., Arlet, G., Goderel, I., and J.C. Rambaud. 1992. Fecal recovery in humans of viable Bifidobacterium sp. ingested in fermented milk. Gastroenterology. 102(3):875-878.
Bernet, M.F., Brassart, D., Neeser, J.R., and A.L. Servin. 1993. Adhesion of human bifidobacterial strains to cultured human intestinal epithelial cells and inhibition of enteropathogen-cell interactions. Appl. Environ. Microbiol. 59(12):4121-4128.
Lievin, V., Peiffer, I., Hudault, S., Rochat, F., Brassart, D., Neeser, J.R., and A.L. Servin. 2000. Bifidobacterium strains from resident infant human gastrointestinal microflora exert antimicrobial activity. Gut. 47(5):646-652.
Saavedra, J.M., Bauman, N.A., Oung, I., Perman, J.A., and R.H. Yolken. 1994. Feeding of Bifidobacterium bifidum and Streptococcus thermophilus to infants in hospital for prevention of diarrhea and shedding of rotavirus. Lancet. 344:1046-1049.
Marteau, P., Pochart, P., Flourie, B., Pellier, P., Santos, L., Desjeux, J.F., and J.C. Rambaud. 1990. Effect of chronic ingestion of a fermented dairy product containing Lactobacillus acidophilus and Bifidobacterium bifidum on metabolic activities of the colonic flora in humans. Am. J. Clin. Nutr. 52:685-688.
Schiffrin, E.J., Brassart, D., Servin, A.L., Rochat, F., and A. Donnet-Hughes. 1997. Immune modulation of blood leukocytes in humans by lactic acid bacteria: criteria for strain selection. Am. J. Clin. Nutr. 66:515S-520S.
Gill, H.S., Rutherfurd, K.J., Cross, M.L., and P.K. Gopal. 2001. Enhancement of immunity in the elderly by dietary supplementation with the probiotic Bifidobacterium lactis HN019. Am J Clin Nutr. 74(6):833-839.
Shu, Q., and H.S. Gill. 2001. A dietary probiotic (Bifidobacterium lactis HN019) reduces the severity of Escherichia coli O157:H7 infection in mice. Med. Microbiol. Immunol. 189(3):147-152.
Kalliomaki, M., Kirjavainen, P., Eerola, E., Kero, P., Salminen, S., and E. Isolauri. 2001. Distinct patterns of neonatal gut microflora in infants in whom atopy was and was not developing. J. Allergy Clin. Immunol. 107:129-134.
Cai, Y., Matsumoto, M., and Y. Benno. 2000. Bifidobacterium lactis Meile et. Al. 1997 is a subjective synonym of Bifidobacterium animalis (Mitsuoka 1969) Scardovi and Trovatelli 1974. Microbiol. Immunol. 44:815-820.
Wagner, R.D., Pierson, C., Warner, T., Dohnalek, M., Farmer, J., Roberts, L., Hilty, M., and E. Balish. 1997. Biotherapeutic effects of probiotic bacteria on candidiasis in immunodeficient mice. Infect. Immun. 65:4165-4172.
Ruiz-Palacios, G. F., Tuz, F., Arteaga, M. L., Guerrero, M. L., Dohnalek, M., and M. Hilty. 1999. Tolerance and fecal colonisation with Lactobacillus reuteri in children fed a beverage with a mixture of Lactobacillus spp. Pediatr. Res. 39(2):104 (abstr).
Ruiz-Palacios, G. F., Guerrero, M., Hilty, M., Dohnalek, P., Newton, P., Calva, J.J., Tostigan, T., Tuz, F., and M.L. Arteaga. 1999. Feeding of a probiotic for the prevention of community acquired diarrhea in young Mexican children. Pediatr. Res. 39(2): 104 (abstr).
Aguirre, M. and M.D. Collins. 1993. Lactic acid bacteria and human clinical infections. J. Appl. Bact. 75:95-107.
Gasser, F. 1994. Safety of lactic acid bacteria and their occurrence in human clinical infections. Bull Inst Pasteur 92: 45-67.
Salminen S., von Wright, A., Morelli, L., Marteau, P., Brassart, D., de Vos, W.M., Fonden, R., Saxelin, M., Collins, K., Mogensen, G., Birkeland, S.-E., and T. Mattila-Sandholm. 1998. Demonstration of safety of probiotics-a review. Int. J. Food Prot. 44:93-106.
Miller-Catchpole, R. 1989. Bifidobacteria in clinical microbiology and medicine. In Besrokovainy and Miller-Catchpole, (eds.), Biochemistry and physiology of bifidobacteria, CRC Press, Boca Raton, Florida.
Borriello, S.P., Hammes, W.P., Holzapfel, W., Marteau, P., Schrezenmeir, J., Vaara, M., and V. Valtonen. 2003. Safety of probiotics that contain lactobacilli or bifidobacteria. Clin. Infect Dis. 36:775-780.
Average Rating
Customer Reviews
Improved digestion
12/27/2011
Reviewed by Mari from Providence RI.
I've been taking 1 tablet each day for a month or so and feel this has definitely improved my digestion.
One of The best Probiotic powders yet!!
9/16/2011
Reviewed by Daniel from Mississippi.
I have been suffering from Candida for about
a year from indoor black mold, overly acidic diet and not realizing about our bodies needing Alkalinity and a 7.365 balance.
Thanks to Dr. Mann Agoura Hills Center for Healing in Beverly Hills with her Patch Adams hospitality staff...Robin.... and off course curezone.com... I am now feeling better with less symptoms and more balance.
Thanks to Rockwell nutrition I was able to order this with a cold pack and the extra cold pack with next day delivery and the powder was cold as a refrigerator!!!!!
Probiotic
7/24/2011
Reviewed by Robin Ashwood from Rodney.
I have alot of stomach problems, this product is by far the best I have tried!
good stuff
6/2/2011
Reviewed by healthymomma from Pennsylvania.
The probiotic works well and I am pleased with my purchase. I will definitely recommend this product to anyone.
Designs for Health Probiatic
10/6/2010
Reviewed by I. Miklos from Brooklyn, New York.
In the past I ordered the product in pill form and this time I accidently ordered it in powder form. I like the product very much, but I will not make the mistake of ordering it in powder form again; it is messy.
Excellent Probiotic
2/11/2010
Reviewed by Happy from Pittsboro NC.
Great product. Keeps my intestines happy. Have tried many types over the years and this one is the best. The only drawback is the shape -- a round sphere which can be slightly difficult to swallow -- but not too difficult to turn me away. They are still my first choice.
feeling good
12/8/2009
Reviewed by Renee from Minneapolis, MN.
My naturopath suggested this product and I have been happy with the results. I really like the fact that it can be taken with food as many others need to be taken on an empty stomach, which requires more planning. I plan to continue taking this indefinitely.
works best
11/30/2009
Reviewed by Lynn from Golden CO.
I have been so pleased with these tiny sphere pills. One each evening has eliminated my intestinal discomfort.
excellent product
1/12/2009
Reviewed by Fleur from Fort Worth, TX.
I have Chron''s disease and went to a naturopath who suggested this probiotic in combination with GI-Microbiotix and Digestizmes. Now I have almost no symptoms and have lost 9 lbs. The powdered form of this probiotic is my favorite and it tastes fine, but I always take it before a meal as it sometimes sticks to the roof of my mouth! This is a great product!
Healthy, stable, tolerant digestive system
10/13/2008
Reviewed by G Ferguson from Suwanee, GA.
I have suffered from Crohn''s disease in the past and, though my Crohn''s has been in remission for years, my digestive system was very reactive. I began taking this particular probiotic at the advice of my nutritionist. Since then my digestive tract has been much healthier. I am less susceptible to the effects of too much stress and not enough sleep and my "system" is much more stable and "tolerant" when I stray from an ideal diet.