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Q-Avail (CoQ10) softgels by Designs For Health (DFH)

60mg
Q-Avail (CoQ10) softgels by Designs For Health (DFH)
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Q-Avail (CoQ10)

Improved! March 2010 Q-Avail? now has even better absorption! (read more about this form of CoQ10 below and why its better than all other CoQ10 in the More Info tab).

Q-Avail? is designed for optimal absorption, stability and cost-efficiency. Oral supplementation with CoQ10 is often desired to improve immune function, mitochondrial metabolism and energy production in the support of fatigue-related disorders, the enhancement of athletic performance, periodontal problems and the support of cardiomyopathy and neurodegenerative conditions such as Parkinson?s. CoQ10 has also been demonstrated to be an effective antioxidant, reducing lipid peroxidation.

Benefits of CoQ10 include:

  • Cholesterol Oxidation Prevention
  • Heart Health
  • Blood Pressure
  • Immune Function
  • Alzheimer?s Disease
  • Periodontal Disease
  • Cancer
  • Miscarriages
  • Ulcers
  • Diabetes
  • Huntington?s Disease
  • Multiple Sclerosis
  • Obesity
  • HIV
  • Increases sperm count

Coenzyme Q10 60 mg
Serving Size:  60 Softgels
Each softgel contains:
  • Coenzyme Q10 60 mg (Japanese, Naturally Fermented)
  • Proprietary Blend 768 mg:
    • CLA [standardized to contain 80% CLA]
    • Organic Flaxseed Oil [standardized to contain 55% [Alpha Linolenic Acid]
    • Monoglyceride.

Other Ingredients: Gelatin, glycerin, water, turmeric (color).

 

Coenzyme Q10 100 mg
Serving Size:  60 Softgels
  • Coenzyme Q10 100 mg   (Japanese . Naturally Fermented)
  • Proprietary Blend 1081 mg:
    • CLA
        [standardized to contain 55% Alpha Linolenic Acid]
    • Organic Flaxseed Oil [standardized to contain 55% [Alpha Linolenic Acid]
    • Monoglyceride
Other Ingredients: Gelatine, glycerin, water, turmeric (color). 
 
These products do not contain: fish, shellfish, peanuts, tree nuts, milk & lactose, eggs, soy, wheat, gluten, artificial colors, flavors or preservatives.
 
Design's for Health new Q-Avail? Coenzyme Q10 softgels use an advanced technology that provides a more efficient and natural method of delivery, offering enhanced absorption and assimilation of ordinary capsules and tablets containing Coenzyme Q10.
 
Recommended Use: As a dietary supplement, take one or more softgels daily with meals or as directed by your health care practitioner.
 

Read customer questions and answers about Nutrition Basics on our blog.

How is this form of CoQ10"Q-Avail" the best absorbed?

Study results show peak absorption of Q-Avail? is 8 times greater than dry powder and two times greater than its toughest competition when compared to dry powder, liposomal, nanoparticle, and partial dissolved in oil formulations. Q-Avail? underwent other clinical trials as well including a 36-hour peak absorption study to determine the total amount of CoQ10 absorbed and a 28-day steady state study to determine the amount of CoQ10 in the blood plasma available for use by the body cells. In these studies, Q-Avail? was compared to a standard dry powder CoQ10 product. The results of the 36-hour absorption study showed that Q-Avail? had a total absorption of 11.65% compared to dry powder having an absorption of 1.32%, which makes Q-Avail ? 783% more absorbable than dry powder. The results of the 28-day steady state study showed that at the end of 28 days there were 8989 ug/ml of Q-Avail? available for use by the cells, compared to 1623 ug/ml of dry powder CoQ10. This makes Q-Avail? 441% more bioavailable than dry powder CoQ10.

Is it important to take CoQ10 if I am on Cholesterol Lowering drugs?
YES! It is extremely important to supplement with CoQ10 while you are on statin medications such as Lipitor since one of their side effects is a lowering of your heart?s natural CoQ10 levels, thus further increasing your risk of heart disease.

Are there any nutrients that help CoQ10 work more effectively?
L-Carnitine, lipoic acid, vitamin E, lycopene, magnesium, and B vitamins all increase the effectiveness of CoQ10.


Essential for Heart Health, Immune Function, and Overall Wellness

COQ10: Essential For Energy
Coenzyme Q10 (CoQ10) is a nutrient that is essential for the body to turn food into energy. CoQ10?s role is similar to that of a spark plug in a car engine. Just as the car cannot function without the initial spark, the human body cannot function without CoQ10. Unfortunately, CoQ10 levels can decline with advancing age. Although CoQ10 is found in all plant and animal sources, optimal doses cannot be achieved through common diets. Organ meats are the richest source of CoQ10, but few eat these foods regularly. Supplementation is therefore needed to achieve optimal CoQ10 levels.

Benefits of CoQ10

  • Promotes Heart Health
  • Lowers Blood Pressure
  • Inhibits Cholesterol Oxidation
  • Helps Periodontal Disease
  • Enhances Immune Function
  • Parkinson?s Disease[7]

    Supporting Heart Health
    CoQ10 is one of the most important nutrients for maintaining the health of the heart. The heart contains twice as much CoQ10 as any other organ or tissue in the body. CoQ10 is needed for the heart to keep up its constant production of energy. CoQ10 can even help heal the hearts of those slated for heart transplants so that they no longer need them.[1] A wide range of heart conditions benefit from CoQ10 supplementation, including angina, mitral valve prolapse, and perhaps cardiomyopathies and congestive heart failure. Paradoxically, medications thought to promote heart health may lower CoQ10 levels. Lovastatin can decrease levels of CoQ10, sometimes to the point of leading to heart and liver damage.[2] Those on statin medications should supplement with CoQ10.

    Lowering Blood Pressure
    One hundred milligrams of CoQ10 per day has been found to lower blood pressure while also raising protective HDL cholesterol and lowering total cholesterol.[3]

    Enhancing Immune Function
    Studies indicate CoQ10 may have dramatic immune-enhancing effects. Older adults as well as those with HIV in particular may benefit from CoQ10.[4]

    Promoting Gum Health
    CoQ10 may help those with periodontal disease heal their gums more quickly. Topical application of CoQ10 may be more effective than taking it orally.[5]

    Supporting Cancer Patients
    Cancer patients taking chemotherapy drugs that are associated with heart toxicity such as adriamycin should consider CoQ10 because it can reduce the toxicity of these drugs. One human study suggested that 390 mg of CoQ10 per day may help support overall wellness and recovery in those with breast cancer.[6]

    Supplement Suggestions For COQ10
    The therapeutic dosage range of CoQ10 is 30 to 400 mg per day. Consuming CoQ10 with an oil or fat improves absorption unless you buy a supplement that provides the fat source along with the CoQ10. If you are taking any medications, or are using CoQ10 to help with any health condition, take it with the guidance of your health care practitioner.

    A Smart and Efficient CoQ10 Supplement!
    With prices of CoQ10 historically the most volatile in the supplement industry, it is essential that your CoQ10 supplement be designed with efficiency and cost effectiveness in mind. It is no longer practical to just use high doses to overcome low absorption rates. Q-Avail? is designed and produced for higher absorption and CoQ10 stability to deliver superior clinical outcomes with more cost-efficiency than other commonly used forms of CoQ10. In a recent in-house study being prepared for publication, Q-Avail? was demonstrated to result in higher peak absorption and higher serum CoQ10 levels after a 2-week supplementation period compared to other forms of CoQ10, including dry powder and popular sublingual forms.

    Oral supplementation with CoQ10 is often desired to improve mitochondrial metabolism and energy production in the treatment of fatigue-related disorders, the enhancement of athletic performance, and the treatment of cardiomyopathy. CoQ10 has also been demonstrated to be an effective antioxidant, reducing lipid peroxidation. CoQ10 is a lipid soluble, high molecular weight, hydrophobic molecule. These molecular properties present problems with oral supplementation viability. CoQ10 has a tendency to crystallize in the stomach and is inherently difficult to absorb. As CoQ10 supplements are comparatively expensive, with costs remaining very volatile in the past few years, there is a great desire on the part of prescribing clinicians to determine the most economical form of CoQ10 which will deliver clinical efficacy. Many proprietary forms of CoQ10 commercially available claim some aspect of novelty and increased absorption, often at the expense of much higher pricing, but do they really deliver? At Designs for Health we have conducted absorbability studies to assure that Q-Avail? truly is a superior and effective choice. DFH's in-house study compared the absorption by measuring the average increase serum CoQ10 levels over a 6-hour period and the total serum CoQ10 levels after a 2-week supplementation with 100 mg of various forms of CoQ10. A brief summary of results appears below:

    CoQ10 Form

    Average increase from baseline
    (over 6-hours)

    Q-Avail?

    1.23 mcg/L

    Dry CoQ10 powder

    0.60 mcg/L

    CoQ10 Form

    Average absolute increase from baseline
    (after 2-weeks supplementation)

    Q-Avail?

    1.06 mcg/L

    Sublingual CoQ10

    0.50 mcg/L

    Dry CoQ10 powder

    0.48 mcg/L

    Results summary:
    * Q-Avail? 100 mg softgels resulted in a 112% greater absolute increase in serum CoQ10 than sublingual CoQ10 and a 121% greater absolute increase than dry CoQ10 powder.
    * Oral supplementation with 100mg of Q-Avail? resulted in 105% higher average increase from baseline in serum CoQ10 over 6-hours, as compared to dry CoQ10 powder.

    The superior bioavailability of this CoQ10 formulation is dependent on novel technology that keeps the crystalline structure in liquid heterogeneity using bee wax, rice bran oil, D. salina; the mixed tocopherols are included in the softgel for stability. The softgel is colored naturally with annatto and tumeric and contains no artificial ingredients.

    Click here to download CoQ10 PDF file: Heart Health, Immune Function, and Overall Wellness Research
    Click here to download Q-Avail PDF file

  • Liu ZX, Artmann C.
    Altern Ther Health Med. 2009 Mar-Apr;15(2):42-6.PMID: 19284181 [PubMed - indexed for MEDLINE]
     
    Ullmann U, Metzner J, Schulz C, Perkins J, Leuenberger B.
    J Med Food. 2005 Fall;8(3):397-9.PMID: 16176154 [PubMed - indexed for MEDLINE]
     
    Schulz C, Obermller-Jevic UC, Hasselwander O, Bernhardt J, Biesalski HK.
    Int J Food Sci Nutr. 2006 Nov-Dec;57(7-8):546-55.PMID: 17162333 [PubMed - indexed for MEDLINE]
     
    Joshi SS, Sawant SV, Shedge A, Halpner AD.
    Int J Clin Pharmacol Ther. 2003 Jan;41(1):42-8.PMID: 12564745 [PubMed - indexed for MEDLINE]
     
    Relative bioavailability of two forms of a novel water-soluble coenzyme Q10.
    Zmitek J, Smidovnik A, Fir M, Prosek M, Zmitek K, Walczak J, Pravst I.
    Ann Nutr Metab. 2008;52(4):281-7. Epub 2008 Jul 22.PMID: 18645245 [PubMed - indexed for MEDLINE]
     
    Comparison of bioavailability of two ubidecarenone products in healthy Korean volunteers.
    Kang EY, Choi JW, Gwak HS, Chun IK.
    Int J Clin Pharmacol Ther. 2009 Mar;47(3):207-14.PMID: 19281730 [PubMed - indexed for MEDLINE]
     
    Relative bioavailability and antioxidant potential of two coenzyme q10 preparations.
    Kurowska EM, Dresser G, Deutsch L, Bassoo E, Freeman DJ.
    Ann Nutr Metab. 2003;47(1):16-21.PMID: 12624483 [PubMed - indexed for MEDLINE]
     
    Relative bioavailability of coenzyme Q10 formulations in human subjects.
    Chopra RK, Goldman R, Sinatra ST, Bhagavan HN.
    Int J Vitam Nutr Res. 1998;68(2):109-13.PMID: 9565826 [PubMed - indexed for MEDLINE]
     
    Bioavailability assessment of oral coenzyme Q10 formulations in dogs.
    Zaghloul AA, Gurley B, Khan M, Bhagavan H, Chopra R, Reddy I.
    Drug Dev Ind Pharm. 2002 Nov;28(10):1195-200.PMID: 12476865 [PubMed - indexed for MEDLINE]
     
    Stability and bioequivalence studies of two marketed formulations of coenzyme Q10 in beagle dogs.
    Kommuru TR, Ashraf M, Khan MA, Reddy IK.
    Chem Pharm Bull (Tokyo). 1999 Jul;47(7):1024-8.PMID: 10434405 [PubMed - indexed for MEDLINE]
     
    Similar therapeutic serum levels attained with emulsified and oil-based preparations of coenzyme Q10.
    Lyon W, Van den Brink O, Pepe S, Wowk M, Marasco S, Rosenfeldt FL.
    Asia Pac J Clin Nutr. 2001;10(3):212-5.PMID: 11708311 [PubMed - indexed for MEDLINE]
     
    Improvement in intestinal coenzyme q10 absorption by food intake.
    Ochiai A, Itagaki S, Kurokawa T, Kobayashi M, Hirano T, Iseki K.
    Yakugaku Zasshi. 2007 Aug;127(8):1251-4.PMID: 17666877 [PubMed - indexed for MEDLINE]
     
    Plasma coenzyme Q10 response to oral ingestion of coenzyme Q10 formulations.
    Bhagavan HN, Chopra RK.
    Mitochondrion. 2007 Jun;7 Suppl:S78-88. Epub 2007 Mar 27. Review.PMID: 17482886 [PubMed - indexed for MEDLINE]
     
    Blood CoQ10 levels and safety profile after single-dose or chronic administration of PureSorb-Q40: animal and human studies.
    Nukui K, Yamagishi T, Miyawaki H, Kettawan A, Okamoto T, Belardinelli R, Tiano L, Littarru GP, Sato K.
    Biofactors. 2008;32(1-4):209-19.PMID: 19096118 [PubMed - indexed for MEDLINE]
     
    Comparison of uptake between PureSorb-Q40 and regular hydrophobic coenzyme Q10 in rats and humans after single oral intake.
    Nukui K, Yamagishi T, Miyawaki H, Kettawan A, Okamoto T, Sato K.
    J Nutr Sci Vitaminol (Tokyo). 2007 Apr;53(2):187-90.PMID: 17616008 [PubMed - indexed for MEDLINE]
     
     Self-emulsifying drug delivery systems (SEDDS) of coenzyme Q10: formulation development and bioavailability assessment.
    Kommuru TR, Gurley B, Khan MA, Reddy IK.
    Int J Pharm. 2001 Jan 16;212(2):233-46.PMID: 11165081 [PubMed - indexed for MEDLINE]
     
    Increase of bioavailability of coenzyme Q(10) and vitamin E.
    Wajda R, Zirkel J, Schaffer T.
    J Med Food. 2007 Dec;10(4):731-4.PMID: 18158850 [PubMed - indexed for MEDLINE]
     
    Bioavailability of four oral coenzyme Q10 formulations in healthy volunteers.
    Weis M, Mortensen SA, Rassing MR, M?ller-Sonnergaard J, Poulsen G, Rasmussen SN.
    Mol Aspects Med. 1994;15 Suppl:s273-80.PMID: 7752839 [PubMed - indexed for MEDLINE].
     
    Pharmacokinetic study of deuterium-labelled coenzyme Q10 in man.
    Tomono Y, Hasegawa J, Seki T, Motegi K, Morishita N.
    Int J Clin Pharmacol Ther Toxicol. 1986 Oct;24(10):536-41.PMID: 3781673 [PubMed - indexed for MEDLINE]
     
    Coenzyme Q10: absorption, antioxidative properties, determinants, and plasma levels.
    Kaikkonen J, Tuomainen TP, Nyyssonen K, Salonen JT.
    Free Radic Res. 2002 Apr;36(4):389-97.PMID: 12069102 [PubMed - indexed for MEDLINE]

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    Average Rating
    Customer Reviews
    Q-Avail 9/4/2011
    Reviewed by Juliet Ashtian from St. Thomas, VI.
    This is a great product. It was recommended to me by my nutritionist. The power it packs beats my multivitamin any day.

    Great product 2/26/2011
    Reviewed by Christie from Philadelphia, PA .
    I take this as part of my overall healthcare program. I feel. Like by immune system functions better on it.

    Good stuff!!! 10/27/2010
    Reviewed by Julia from Frederick, MD.
    This is a must in our daily routine at our house. It's one of the few supplements my pharmacist friend says everyone (over 40) should definitely take.

    I'm likin' it 11/27/2009
    Reviewed by jake from louisvile colorado.
    I'll say that as long as I have been using this product (years now) ''I just don't get sick anymore...it is really kinda wierd."

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