Ultimate Antioxidant Full Spectrum

Comprehensive full-spectrum antioxidant protection…

This new powerhouse antioxidant formula combines some of nature’s most potent herbs and spices, along with other well-researched antioxidant compounds. These ingredients were selected due to their ability to protect both water-based and lipid-based body structures and compounds, including cell membranes, LDL cholesterol, proteins, and enzymes.

This formula replaces the need to use the previous Ultimate Antioxidant LS and HS in combination for full spectrum antioxidant protection.

Why?

Recent research proves that synergism is more potent than isolated antioxidant action, and is reflected in this powerful and comprehensive full-spectrum antioxidant formula.

Featured ingredients include:

• Curcumin C3® complex, the most potent source available today; works synergistically with vitamin C, inhibits glutamate-hydroxyl radicals in the hypothalamus.
• Acerola Cherry Malpighia glabra),an antioxidant due to vitamin C and other flavanoids; reduces cell proliferation by activating RAS signal pathways; lung protective properties.
• Grape Seed Extract(Vitis vinifera), antimicrobial, hepatoprotective and protects LDL cholesterol from oxidation.
  Ginkgo biloba, for protection against ionizing radiation, mercury induced tissue damage and protects the brain from cell phone related electromagnetic radiation.
• Full spectrum of the vitamin E family and a broad range of carotenoids, providing a powerful free radical scavenging effect.

Serving Size:
3 capsules

Product Contains:

• Vitamin A (as Natural Mixed Carotenoids Complex) 8300 IU,
• Alpha Carotene 2.5 mg,
• Beta Carotene 5 mg,
• Acerola (Malpighia glabra)(fruit) 400 mg
  [standardized to contain 24% vitamin C],
• High Gamma Mixed Tocopherols 120 mg,
• Grape Seed Extract (vitis vinifera) 90 mg
  [standardized to contain 95% proanthocyanidins],
• Curcumin C3 Complex® 80 mg
  (containing three curcuminoids: curcumin, Bisdemethoxy curcumin, Demethoxy curcumin),
• Garlic (Allium sativum)(bulb) 60 mg,
• Tocotrienols (from Annatto Bean) 30 mg,
• Ginkgo Biloba 25 mg,
• Quercetin 25 mg, Rutin 25 mg,
• Clove (Syzygium aromaticum)(buds) 25 mg,
• Allspice (Pimenta dioca)(berries) 25 mg,
• Sweet Basil (Ocium basilicum)(leaves) 25 mg,
• Sage (Salvia officinalis)(leaves) 25 mg,
• Rosemary 22 mg
  (Rosemarinus officinalus)(ariel),
• Polygonum cuspidatum (root) 10 mg
  [standardized to contain 50% trans resveratrol],
• Lutein (Marigold Lutein Esters) 7.5 mg,
• Lycopene 7.5 mg

Other Ingredients: Microcrystalline cellulose, silicon dioxide, magnesium stearate, stearate acid.

Recommended Use: As a dietary supplement, take three capsules daily with meals or as directed by your health care practitioner.

This product does not contain: wheat, yeast, soy, gluten, eggs, dairy, corn, artificial colors, flavors, sugars, or preservatives.

Recent research proves that synergism is more potent than isolated antioxidant action, and is reflected in this powerful and comprehensive full-spectrum antioxidant formula.

Featured ingredients include:

• Curcumin C3® complex , the most potent source available today; works synergistically with vitamin C, inhibits glutamate-hydroxyl radicals in the hypothalamus.
• Acerola Cherry (Malpighia glabra), an antioxidant due to vitamin C and other flavanoids; reduces cell proliferation by activating RAS signal pathways; lung protective properties.
• Grape Seed Extract (Vitis vinifera), antimicrobial, hepatoprotective and protects LDL cholesterol from oxidation.

Antioxidants are found in combination in nature. These studies prove synergism is stronger than antioxidants taken alone.
1. Lycopene synergistically inhibits LDL oxidation in combination with vitamin E, glabridin, rosmarinic acid, carnosic acid, or garlic. Antioxid Redox Signal.
2000 Fall; 2(3): 491-506. Fuhrman B, Volkova N, et al.
2. Carotenoid mixtures protects multilamellar liposomes against oxidative damage: synergistic effects of lycopene and lutein. FEBS Lett. 1998 May 8;
427(2):305-8. Stahl W, Junghans A, et al.

Acerola cherry as an excellent natural source of antioxidants such as Vitamin C.
3. Effect of acerola cherry extract on cell proliferation and activation of ras signal pathway at the promotion stage of lung tumorigenesis in mice. J Nutr Sci
Vitaminol (Tokyo). 2002 Feb;48(1):69-72. Nagamine I, Akiyama T, et al.
4. Antioxidant activity, ascorbic acid and total phenol of exotic fruits occurring in Brazil. Int J Food Sci Nutr. 2008 Sep 10:1-10. Aparecida de Assis S, Carlos
Rebuglio Vellosa J, et al.

Grape seed polyphenols have been shown to have very high antioxidant power.
5. Polyphenolics in grape seeds-biochemistry and functionality. J Med Food. 2003 Winter;6(4):291-9. Shi J, Yu J, et al.
Curcumin works synergistically with water-soluble antioxidants such as Vitamin C and protects against several free radicals.
6. How curcumin works preferentially with water soluble antioxidants. J Am Chem Soc. 2001 Apr 4; 123(13): 3064-8. Jovanovic SV, Boone CW, et al.
7. Curcumin inhibits the increase of glutamate, hydroxyl radicals and PGE2 in the hypothalamus and reduces fever during LPS-induced systemic inflammation
in rabbits.Eur J Pharmacol. 2008 Sep 28;593(1-3):105-11. Huang WT, et al.

Garlic increases serum antioxidant levels.
8. Garlic increases antioxidant levels in diabetic and hypertensive rats determined by a modified peroxidase method. Evid Based Complement Alternat Med.
2009 Feb 20. Droviova H, Thomson M, et al.

Ginkgo biloba is shown to have antioxidant, anti-angiogenic and gene regulatory actions.
9. Ginkgo biloba extracts and cancer: a research area in its infancy. Fundam Clin Pharmacol. 2003 Aug; 17(4): 405-17. DeFeudis FV, Papadopoulos V, Drieu K.
Ginkgo biloba is shown to protect against oxidative tissue damage.
10. Ginkgo biloba extract protects against ionizing radiation-induced oxidative organ damage in rats. Pharmacol Res. 2006 Mar;53(3):241-52. Sener G,
Kabasakal L, et al.
11. Ginkgo biloba extract protects against mercury(II)-induced oxidative tissue damage in rats. Food Chem Toxicol. 2007 Apr;45(4):543-50. Sener G, Sehirli
O, et al.
12. Ginkgo biloba prevents mobile phone-induced oxidative stress in rat brain. Clin Chim Acta. 2004 Feb;340(1-2):153-62. Ilhan A, Gurel A, et al.
Polyphenols with the greatest number of hydroxyl groups make the best antioxidants such as Quercetin.
13. A new method of measuring the antioxidant activity of polyphenols using cumene hydroperoxide. Ann Clin Biochem. 2004 Jan;41(Pt 1):72-7. Sugita O,
Ishizawa N, et al.

Quercetin has been shown to provide significant protection against oxidative injury.
14. Quercetin Prevents Lipopolysaccharide-induced HMGB1 Release and Proinflammatory Function. Am J Respir Cell Mol Biol. 2009 Mar 5. Tang D, Kang R, et al.
Rutin was found to inhibit the formation of advanced glycation end products.
15. Inhibition of advanced glycation end product formation on collagen by rutin and its metabolites. J Nutr Biochem. 2006 Aug;17(8):531-40. Cervantes-
Laurean D, Schramm DD, et al.

Clove and basil protect against the oxygen radical.
16. Determination of antioxidant activity of herbs by ESR. Shokuhin Eiseigaku Zasshi. 2003 Feb; 44(1): 59-62. Yun YS, Nakajima Y, et al.
Active ingredients of herbs such as allspice and clove are strong hydroxyl radical scavengers (as strong as alpha tocopherol) and protect
against AGE's.
17. Spice constituents scavenging free radicals and inhibiting pentosidine formation in a model system. Biosci Biotechnol Biochem. 1997 Feb;61(2):263-6.
Oya T, Osawa T, Kawakishi S.
18. Several culinary and medicinal herbs are important sources of dietary antioxidants. J Nutr. 2003 May;133(5):1286-90. Dragland S, Senoo H, Wake K, et al.
19. Antioxidative properties of water extracts obtained from herbs of the species Lamiaceae. Int J Food Sci Nutr. 2001 Jul;52(4):313-7. Triantaphyllou K,
Blekas G, Boskou D.

Rosemary compound, rosmarinic acid, protects from lung inflammation and lung edema according to the study below.
20. Rosmarinic acid inhibits lung injury induced by diesel exhaust particles. Free Radic Biol Med. 2003 Apr 15; 34(8): 1060-9. Sanbongi C, Takano H, et al.
Resveratrol is a powerful antioxidant, chemopreventive and anti-inflammatory compound.
21. Resveratrol--a prostate cancer chemopreventive agent? Urol Oncol. 2002 Nov-Dec; 7(6): 223-7. Ratan HL, Steward WP, et al.
Resveratrol reduces ocular inflammation and protects the retina.
22. Resveratrol Prevents Ocular Inflammation in Endotoxin-Induced Uveitis via Inhibiting Oxidative Damage and Nuclear Factor-{kappa}B Activation. Invest
Ophthalmol Vis Sci. 2009 Mar 11. Kubota S, Kurihara T, Mochimaru H, Satofuka S, Noda K, Ozawa Y, Oike Y, Ishida S, Tsubota K.