GI Revive

Comprehensive support of gastrointestinal health and function

Patients with poor gut integrity easily develop food sensitivities and may have compromised nutrient assimilation.

GI Revive is a convenient, crystalline powder that mixes easily into any beverage or other functional food powder.

Capsule or powder provides therapeutic levels of L-glutamine, N-acetyl-glucosamine, MSM, DGL, slippery elm, marshmallow, chamomile, okra, TOA-free cat's claw, quercitin, and mucin for comprehensive support of optimal gastrointestinal health. Prunus and citrus pectin are included to aid regularity.

Powder:

Serving Size: 1 teaspoon (7.5 grams)
Servings per container: 30

L-Glutamine.......1500 mg
N-Acetyl Glucosamine.......1000 mg
Citrus Pectin.......1000 mg
Deglycyrrhizinated Licorice (DGL (Glycyrrhiza glabra).......400 mg
Aloe Vera (Leaf Extract 200:1).......300 mg
Slippery Elm (bark) (Ulmus pulmila).......200 mg
Mucin.......200 mg
Marshmallow (root) (Althea officinalis).......100 mg
Chamomile (Matricaria chamomilla).......100 mg
Okra (pod (Hibiscus esculentus).......100 mg
Cat's Claw (TOA free (bark) (Uncaria tomentosa).......100 mg
Methylsulfonylmethane (MSM).......100 mg
Quercetin.......100 mg
Prunus (Concentrate).......100 mg
PepZin GI (Zinc-Carnosine).......75 mg

Other Ingredients:Natural peach powder, decafe black tea, xylitol, silicon dioxide, xanthan gum, citric acid, soy lecithin, stevia (leaf) extract, beta carotine (color).

Recommended Use
As a dietary supplement, take one teaspoon, one to two times daily, or as directed by your health care practitioner.

Caution:
There is concern that use of N-acetyl glucosamine products derived from exoskeletons of of shrimp, lobster, and crab might cause reactions in people allergic to shellfish, although no reactions have been reported as of August 2009. Until more is known, and because the source of N-acetyl glucosamine products is not listed on product labels, use N-acetyl glucosamine with caution in people with shellfish allergy. There is also some evidence that patients with shellfish allergy can safely take glucosamine products.

Read customer questions and answers about Nutrition Basics on our blog.

GI-Revive

Rejuvenates intestinal mucosal health

Promotes proper intestinal permeability (appropriate for “Leaky Gut”)

Provides healing for ulceration and inflammation

Promotes regularity and healthy bowel function

GI-Revive Features:
Now with Zinc-carnosine
Zinc-carnosine was added to this formulation due to the exciting new literature that has been emerging showing the impressive mucosal protective and anti-ulcerative properties of zinc-carnosine, including the ability to protect the intestinal lining against damage due to indomethacin and other strong anti-inflammatory medications often associated with intestinal mucosal damage.

L-glutamine

The most important nutritional substance for healthy intestinal cells. It is one of the most commonly used amino acids in the body to repair tissues, particularly high turn-over tissue such as the epithelial cells of the intestinal lining. Supplemental L-glutamine has been shown to have immunomodulatory, anticatabolic/anabolic and gastrointestinal mucosal-protective actions. It may also have antioxidant activity as it is a precursor for glutathione synthesis. Under stress, the body relies on glutamine to help meet its extra energy needs. Supplemental L-glutamine is used in medical foods for such stress situations as trauma, cancer, infections and burns.

Glutamine deficiency can cause severe intestinal degradation and supplementation can enhance intestinal healing and repair. L-glutamine is essential in maintaining proper intestinal permeability, and avoiding “leaky gut syndrome”. Leaky gut syndrome can result in increased toxic and allergy exposure, systemic inflammation, and autoimmune disease.

MSM and Quercitin
These antiinflammatory substances can reduce the chronic inflammation which is often the reason why the intestinal lining becomes damaged and “leaky”. Quercitin can also provide direct antiinflammatory action by stabilizing intestinal mast cells and can improve tissue health through its antioxidant functions.

N-acetyl-glucosamine and MSM

Provided to aid in the production of health supportive structures for the cells of the intestinal lining. The increased production of glycosaminoglycans (GAG's), which can occur as a result of supplementation of these nutrients, can help support proper mucosal health and reduce intestinal permeability. In studies on mice, Dr. Michael Demetriou and colleagues with the UC Irvine Center for Immunology found that N-acetylglucosamine (GlcNAc), which is similar but more effective than the widely available glucosamine, shows potential to help those suffering from autoimmune diseases by inhibiting the growth and function of abnormal T-cells that incorrectly direct the immune system to attack specific tissues in the body, such as brain myelin in MS and insulin-producing cells of the pancreas in diabetes. Study results appear a 2007 paper in the Journal of Biological Chemistry. This study comes on the heels of others showing the potential of GlcNAc in humans. One previous clinical study reported that 8 of 12 children with treatment-resistant autoimmune inflammatory bowel disease improved significantly following two years of treatment with GlcNAc. No significant adverse side effects were noted.

DGL, Slippery Elm, Marshmallow, Chamomile, Okra, and TOA-free Cat's Claw
These mucilaginous and relaxing herbs can provide comprehensive enhancement of intestinal function by coating and soothing the intestinal lining, promoting the healing of ulcers and inflamed tissue, and reducing cramping by relaxing the intestines. GI Revive contains this impressive comprehensive blend of botanicals that have a long traditional use in gastrointestinal disorders.

Mucin

A glycoprotein, normally secreted by the intestinal epithelial cells, containing sialic acid and N-neurominic acid. Mucin can serve to coat the intestinal lining and to neutralize intestinal antigens, along with sIgA, reducing the inflammation and tissue damage caused by food allergy, intestinal infection and dysbiosis.

Prunus and Citrus pectin

Included to safely aid in regularity without the caustic and damaging effects of commonly used herbal laxatives such as Cassia marilandica (senna) and Rhamnus purshiana (cascara sagrada).

Klimberg, V. Suzanne, M.D., et al. Prophylactic Glutamine protects the intestinal mucosa from radiation injury. Cancer 1990, July 1;66(1):62-68.
Hickson R, et al. Glutamine prevents downregulation of myosin heavy chain synthesis and muscle atrophy from glucocorticoids. Am J Physiol 1995 Apr;268(4 Pt 1):E730-E734.
Noyer CM, Simon D, Borczuk A, Brandt LJ, Lee MJ, Nehra V. A double-blind placebo-controlled pilot study of glutamine therapy for abnormal intestinal permeability in patients with AIDS. Am J Gastroenterol 1998;93(6):972-5.
Foitzik T, Stufler M, Hotz HJ, Klinnert J, Wagner J, Warshaw AL, Schulzke JD, Fromm M, Buhr HJ. Glutamine stabilizes intestinal permeability and reduces pancreatic infection in acute experimental pancreatitis. J Gastrointest Surg. 1997;1(1):40-47.
Herschler RJ. Dietary and pharmaceutical uses of methylsulfonylmethane and compositions comprising it. United States Patent 4,514,421:April 30, 1985.
Hutter JA et al., Anti-inflammatory C-glucosyl chromone from Aloe barbadensis. In: JNP 59(5):541-543, 1996.
Langmead L, et al. Antioxidant effects of herbal therapies used by patients with inflammatory bowel disease: an in vitro study. Aliment Pharmacol Ther., 2002 Feb;16(2):197-205.
Hough L, Jones JK, Hirst EL. Chemical constitution of slippery elm mucilage; isolation of 3-methyl d-galactose from hydrolysis products. Nature, 1950 Jan; 165(4184):34.
Lengsfeld C, Titgemeyer F, Faller G, Hensel A. Glycosylated compounds from okra inhibit adhesion of Helicobacter pylori to human gastric mucosa. J Agric Food Chem. 2004; Mar 24;52(6):1495-503.
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Mahmood A, FitzGerald AJ. Zinc carnosine, a health food supplement that stabilizes small bowel integrity and stimulates gut repair processes. Gut. 2007 Feb;56(2):168-75. Epub 2006 Jun 15
Odashima M. Zinc L-carnosine protects colonic mucosal injury through induction of heat shock protein 72 and suppression of NF-kappaB activation. Life Sci. 2006 Nov 10;79(24):2245-50. Epub 2006 Aug 2.
Mikami K, Otaka M, Watanabe D. Zinc L-carnosine protects against mucosal injury in portal hypertensive gastropathy through induction of heat shock protein 72. J Gastroenterol Hepatol. 2006 Nov;21(11):1669-74.
Morgan R, Gao G, Pawling J, Dennis JW, Demetriou M, Li B. N-acetylglucosaminyltransferase V (Mgat5)-mediated N-glycosylation negatively regulates Th1 cytokine production by T cells. J Immunol. 2004 Dec 15; 173(12):7200-8.

UPC 87945200343

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Customer Reviews
Average Rating on 1 Reviews Write a Review (05 stars in 1 rating(s))
*Colitis*			10/18/2012
Reviewed by Drew from Vermont.
I was first recommended this stuff during a flare up. It works great for me. Helping to stop diarrhea and also give more control and less urgency. 1 tsp morning and 1 @ night really helps me. Thank you. If you try it give it a few weeks. And if you hate the taste at first keep using it because you get used to it and the benefits totally make it worth it.

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GI Revive 450g powder by Designs For Health (DFH)

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GI Revive