Cal//Mag 1001 tablets from Douglas Laboratories provide 500 mg of elemental calcium from a calcium complex and 500 mg of magnesium complex to yield a 1:1 calcium to magnesium ratio. Other nutrients are also included to assist the body in maintaining healthy bone structure.
INDICATIONS
Cal//Mag 1001 may be a useful dietary supplement for those who wish to increase their intake of calcium and other nutritional factors for maintaining good bone health.
SUGGESTED USE Adults take 3 tablets daily or as directed by a healthcare professional.
SIDE EFFECTS No adverse side effects have been reported.
STORAGE Store in a cool, dry place, away from direct light. Keep out of reach of children.
FUNCTIONS
The adult human body contains approximately 1,200 g of calcium, about 99% of which is present in the skeleton, and 20-30 g of magnesium with about 60% located in bone. Bone is constantly turning over, a continuous process of formation and resorption. In children and adolescents, the rate of formation of bone mineral predominates over the rate of resorption. In later life, resorption predominates over formation. Therefore, in normal aging, there is a gradual loss of bone. Intestinal calcium absorption ranges from 15 to 75% of ingested calcium. Vitamin D is a key regulatory hormone for calcium and bone metabolism. Adequate vitamin D status is essential for ensuring normal calcium absorption and maintenance of healthy calcium plasma levels. Magnesium absorption is independent of vitamin D status and ranges from 30 to 60% of ingested magnesium. Osteoporosis, a condition of reduced bone mineral density that can increase risk of fractures, affects a large proportion of the elderly in developed countries. Caucasian and Asian women typically have low peak bone densities, and therefore, are at the greatest risk of developing osteoporosis. It is generally accepted that obtaining enough dietary calcium throughout life can significantly decrease the risk of developing osteoporosis. Among other factors, such as regular exercise, gender and race, calcium supplementation during childhood and adolescence appears to be a prerequisite for maintaining adequate bone density later in life. But even elderly osteoporotic patients can benefit significantly from supplementation with dietary calcium. Cal/Mag 1001 provides a beneficial source of dietary calcium together with other nutrients that assist in the maintenance of healthy bone structure and function. For example, boron affects the composition, structure, and strength of bone. It appears to be necessary for calcium and magnesium absorption, their adequate renal reabsorption, and their incorporation into the bone matrix. Boron is absorbed at about 90% efficiency and is rapidly distributed among the tissues.
REFERENCES
Bendich A, Leader S, Muhuri P. Supplemental calcium for the prevention of hip fracture: potential healtheconomic benefits. Clin Ther 1999;21:1058-72. Castelo-Branco C. Management of osteoporosis. An overview. Drugs Aging 1998;12:25-32. Chapin RE, Ku WW, Kenney MA, et al. The effects of dietary boron on bone strength in rats. Fundam Appl Toxicol 1997;35:205-15. Dimai HP, Porta S, Wirnsberger G, et al. Daily oral magnesium supplementation suppresses bone turnover in young adult males. J Clin Endocrinol Metab 1998;83:2742-8. Laketic-Ljubojevic I, Suva LJ, Maathuis FJ, et al. Functional characterization of N-methyl-D-aspartic acid-gated channels in bone cells. Bone 1999;25:631-7. Morton DJ, Barrett-Connor EL, Schneider DL. Vitamin C supplement use and bone mineral density in postmenopausal women.[In Process Citation]. J Bone Miner Res 2001;16:135-40. New SA, Robins SP, Campbell MK, et al. Dietary influences on bone mass and bone metabolism: further evidence of a positive link between fruit and vegetable consumption and bone health? Am J Clin Nutr 2000;71:142-51. O'Brien KO. Combined calcium and vitamin D supplementation reduces bone loss and fracture incidence in older men and women. Nutr Rev 1998;56:148-50. Reid IR. The roles of calcium and vitamin D in the prevention of osteoporosis. Endocrinol Metab Clin North Am 1998;27:389-98. Rude RK, Kirchen ME, Gruber HE, et al. Magnesium deficiency induces bone loss in the rat. Miner Electrolyte Metab 1998;24:314-20.
UPC 310539015780
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