0 Items in Bag | Total: $0 USD
Contact Us
1.866.757.4500
Back To School
Recommended
Nutritionist favorites
Brands
BioGenesis
Designs For Health
Health Practitioner Brands
Other Brands
Health Concerns
Addiction Recovery
Adrenal Fatigue
Adult Attention Deficit
Allergies
Anti-Aging
Arthritis & Joint Support
Athlete's Foot
Autoimmune Diseases
Baby Health ages 0-2
Bariatric Surgery Nutrition
Blood Sugar Issues
Bone Health & Osteoporosis
Brain Health
Cancer
Candida & Yeast
Cardiovascular Support
Children's Health ages 2-12
Circulation Support
Cold and Flu Support
Detox & Cleansing
Digestive GI Health
Ear Support
Emotional Well Being
Energy & Fatigue
Eye Health
Food Poisoning
Gout
Headache
Healthy Seniors
Hepatitis C
Herpes
Hormone Balance
Immune Support
Inflammation & Pain
Kidney Health & Kidney Stones
Lyme Disease
Mens Health
Muscle Cramps
Nervous System Support
Oral Health
Pet Health
Respiratory Health
Skin, Hair & Nails
Sleep Support
Sports Nutrition
Systemic Lupus
Thyroid Hormone Support
Travel Sickness
Urinary Support
Weight Loss
Women's Health
Wound Healing
Supplement Categories
Amino Acids
Antioxidant Formulas
Aromatherapy
Calcium and Magnesium
Dairy Free
Enzymes
Face and Body Care
Fiber
Fish Oils
Herbal
Homeopathics
Minerals
Multivitamins
Osteo Support Formulas
Probiotics
Protein Powders
Vitamins
Whole Food Supplements
Food Categories
Edible Oils
Protein Bars
Sea Salt
Seeds
Backordered Items
Currently Unavailable
Whats New!
Recently Added
Organic Hemp Protein - Vanilla 1 lb by Manitoba Harvest
Organic Hemp Protein - Vanilla 1 lb by Manitoba Harvest
Rockwell Nutrition has gone GREEN!

More Information

Curaphen 120 vcaps by Euromedica

120 vcaps
Today's Price:
$66.95

This item is IN STOCK
QTY

Rockwell Nutrition Reward Points

Earn 67 Points when you buy this item! Learn More

Curaphen

Professional Pain Formula
Safe and Effective

CLINICALLY STUDIED BCM-95® CURCUMIN
and BosPure® Boswellia

Curaphen® is for pain relief. This unique and proprietary formula supports a healthy inflammation response, duration of endorphin/enkaphalin effect, healthy circulation, and modulation of fibrinogen deposition in muscle tissue. BCM-95® curcumin, has been shown to have up to 10 times better absorption than plain curcumin and BosPure® boswellia is purified to remove potentially harmful levels compounds called beta-boswellic acids, while retaining >10% AKBA.


Recommendations: One capsule three times daily, or as directed by your healthcare practitioner.

Serving Size: 1 Capsule
Servings Per Container: 120
Amount per Serving: 725 mg

DLPA (dl Phenylalanine),Boswellia (Boswellia serrata) Gum Resin Extract (BosPure®) standardized to contain >70% Total Organic and Boswellic Acids with AKBA >10%, with less than 5% beta-boswellic acids, Curcumin (Curcuma longa) Rhizome Extract (BCM-95®) standardized for curcuminoid complex (curcumin, demethoxycurcumin and bisdemethoxycurcumin), Nattokinase

Other Ingredients: vegetable cellulose capsules, vegetable source magnesium stearate, silicon dioxide. Contains Soy (less than 5 parts per million)

Contains no: sugar, salt, yeast, wheat, gluten, corn, dairy products, artificial coloring, artificial flavoring, or preservatives. Color variations are normal.

VEGAN

Occasional muscle pain due to exercise or overuse.
All ingredients established in human studies for safety and effectiveness.
Does not interfere with stomach, liver or kidney function.

BosPure® and BCM-95® are registered trademarks of Dolcas-Biotech

If pregnant or nursing, consult a health care practitioner before using.

Made in the USA


Questions about dosing: Should CuraPro & CuraPhen be taken after a meal? Or is there a better time to take these & can they be used together for additional support?

Answer from EuroMedica: We recommend that most supplements be taken with meals or food as most people have better absorption this way and it eliminates any risk of upset stomach for those who have sensitivities.

However, I have heard of people taking these at all times and with and without food with excellent results. Yes Curaphen and CuraPro can be used together for additional support.

CuraPro is a very high dose of just one ingredient, our clinically proven BCM-95 curcumin. Curaphen is our professional pain formula. It contains a much smaller dose of BCM-95 curcumin and 3 other products that work together to address pain issues.

BCM-95 has been proven to have a blood retention time of 8-12 hours. With that said, I would dose a morning and an evening dose of Curaphen for those who are really struggling with pain control. Or Morning, noon, and night.

Curaphen® is a combination of four clinically studied ingredients that are designed to address pain: BCM-95® bioavailable curcumin, Bos-Pure® standardized boswellia extract, dl-phenylalanine, and nattokinase.

BCM-95® curcumin:
Curaphen® contains a uniquely bioavailable form of curcumin called BCM-95®. Curcumin is a compound from turmeric, used traditionally as a spice, food ingredient, and as a botanical in Ayurvedic medicine. Benefits associated with curcumin include: immune system modulation, protection from oxidative stress, and support for the body's natural inflammatory response. However, although curcumin has shown great promise for these many benefits, it is not easily absorbed.
Efforts to make curcumin more bioavailable have included standardization (to 95%), and combining with lecithin and/or piperine. While standardization is common, it still hasn't resulted in absorption and plasma levels of curcumin needed to see the most benefit. In fact, clinical trials have used increasingly larger dosages (up to 10-12 grams daily) in order to get even a small amount into the bloodstream. Adding lecithin is one option that does increase absorption to a point (up to 5-fold in a small rat study), but piperine presents potential issues with significant prescription interactions and liver function. Fortunately, one curcumin extract – BCM-95® -- has been clinically tested and shown to have up to 10 times the bioavailability and greater blood retention time than standard 95% curcumin extracts, and 6.3 times more than curcumin complexed with lecithin and piperine. It is this curcumin formula that is featured in Curaphen.


Absorption:
This chart shows the difference in absorption between the BCM-95® and curcumin complexed with piperine or lecithin.


Ingredient Purpose in Curaphen®
BCM-95® curcumin: Clinically tested and shown to have up to 10 times the bioavailability and greater blood retention time than standard 95% curcumin extracts, and 6.3 times more than curcumin complexed with lecithin and piperine. Benefits associated with curcumin include: immune system modulation, protection from oxidative stress, and support for the body's natural inflammatory response. Inhibits multiple inflammation pathways in the body, including COX-2
Bos-Pure® boswellia
Boswellic acids are most associated with support of the body's inflammatory response, but not all boswellic acids have beneficial effects. In fact, the presence of the less desirable beta-boswellic acid, can potentially promote, rather than block, inflammatory compounds. Bos-Pure® is screened in a manner that reduces beta-boswellic acid content to less than 5%, and assures that at least 15% or more of the extract includes acetyl-11-keto-β-boswellic acid (AKBA) – that greatly increases its benefit. Bos-Pure has up to a 2-fold greater impact on natural inflammatory factors compared to standard boswellia extracts.
Helps reduce 5-LOX (lipoxygenase) activity, and works synergistically with curcumin to relieve pain.
DLPA (D,L – phenylalanine):
The amino acid DLPA contains the "D" and "L" forms, and each contributes to the formula.
The "D" form of DPLA inhibits the breakdown of compounds called enkephalins, which are related to endorphins, and are associated with positive mood. Enkephalins are also shown to relieve occasional muscle pain due to exercise or overuse.The "L" form improves mood-elevating chemicals in the brain, such as dopamine, epinephrine, and norepinephrine which can have a significant impact on pain.
Nattokinase:
Nattokinase is an enzyme extract of the fermented soy food, natto.
Helps promote blood flow, aiding the other ingredients in Curaphen to reach all areas of the body. Also helps support balanced fibrinogen levels in the body. Excess fibrinogen levels have been noted in post-exercise muscle pain and occasional muscle strain.20

Tested ingredients:

The ingredients in Curaphen® are robust, well-studied and intended for everyday use. The charts above and below illustrate the differences between BCM-95 curcumin and Bos-Pure boswellia extract compared to commonly recommended preparations of the same botanicals.


The Bos-Pure® difference:

Conclusion:

A natural intervention to support the body's own natural anti-inflammatory abilities is important for practitioners and patients alike. Curaphen provides the powerful ingredients necessary to be a professional pain formula.

Occasional pain and inflammation due to exercise or overuse.

Dosage: 1 capsule 3 times daily or as directed by your healthcare professional.

1. Antony B, Merina B, Iyer VS, Judy N, Lennertz K, Joyal S. A pilot cross-over study to evaluate human oral bioavailability of BCM-95 CG (Biocurcumax™) a novel bioenhanced preparation of curcumin. Ind J Pharm Sci. 2008:445-449.
2. Jurenka JS. Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. Altern Med Rev. 2009;14(2):141-53.
3. Jacob A, Wu R, Zhou M, Wang P. Mechanism of the Anti-inflammatory Effect of Curcumin: PPAR-gamma Activation. PPAR Res. 2007;89369.
4. Johnson SM, Gulhati P, Arrieta I, et al. Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling. Anticancer Res. 2009;29(8):3185-90.
5. Ravindran J, Prasad S, Aggarwal BB. Curcumin and cancer cells: how many ways can curry kill tumor cells selectively? AAPS J. 2009;11(3):495-510.
6. Seehofer D, Schirmeier A, Bengmark S, et al. Curcumin Attenuates Oxidative Stress and Inflammatory Response in the Early Phase after Partial Hepatectomy with Simultaneous Intraabdominal Infection in Rats. J Surg Res. 2008 Dec 31.
7. Biswas S, Rahman I. Modulation of steroid activity in chronic inflammation: a novel anti-inflammatory role for curcumin. Mol Nutr Food Res. 2008;52(9):987-94.
8. Benny B, Antony B. Bioavailability of Biocurcumax (BCM-95). Spice India. September, 2006:11-15.
9. Ammon HP. Boswellic acids in chronic inflammatory diseases. Planta Med. 2006;72(12):1100-16.
10. Poeckel D, Tausch L, Altmann A, et al. Induction of central signaling pathways and select functional effects in human platelets by beta-boswellic acid. Br J Pharmacol. 2005;146(4):514-24.
11. Ehrenpreis S. Analgesic properties of enkephalinase inhibitors: animal and human studies. Prog Clin Biol Res. 1985;192:363-370.
12. Ehrenpreis S. D-phenylalanine and other enkephalinase inhibitors as pharmacological agents: implications for some important therapeutic application. Acupunct Electrother Res. 1982;7(2-3):157-72.
13. DPLA. In: Hendler SS, ed. PDR for Nutritional Supplements. 2nd ed. Montvale, NJ: Physician's Desk Reference; 2008:189.
14. Walsh NE, Ramamurthy S, Schoenfeld L, Hoffman J. Analgesic effects of D-phenylalanine in chronic pain patients. Arch Phys Med Rehabil. 1986 Jul;67(7):436-9.
15. Russell AL, McCarty MF. DL-phenylalanine markedly potentiates opiate analgesia –- and example of nutrient/pharmaceutical up-regulation of the endogenous analgesia system. Med Hypotheses. 2000 Oct;55(4):283-8.
16. Beckmann H, Strauss MA, Ludolph E. DL-phenylalanine in depressed patients: an open study. J Neural Transm. 1977;41(2-3):123-34.
17. Beckmann H, Athen D, Oltheanu M, et al. DL-phenylalanine versus imipramine: a double-blind controlled study. Arch Psychiatr Nervenkr. 1979 Jul 4;227(1):49-58.
18. Hsia CH, Shen MC, Lin JS, et al. Nattokinase decreases plasma levels of fibrinogen, factor VII, and factor VIII in human subjects. Nutr Res. 2009 Mar;29(3):190-6.
19. Fujita M, Hong K, Ito Y, Fujii R, Kariya K, Nishimuro S. Thrombolytic effect of nattokinase on a chemically-induced thrombosis model in rat. Biol Pharm Bull. 1995 Oct;18(10):1387-91.
20. Ribeiro J, Almeida-Dias A, Oliveira AR, Mota J, Appell HJ, Duarte JA. Exhaustive exercise with high eccentric components induces prothrombotic and hypofibrinolytic responses in boys. Int J Sports Med. 2007 Mar;28(3):193-6.

Manufacturer: Euromedica
SKU: 60220


Customer Reviews
Average Rating on 1 Reviews
(04 stars in 1 rating(s))
4 star rating Curaphen vcaps 11/14/2012 Curaphen 120 vcaps by Euromedica4
Reviewed by Pamela from Charleston, SC.
I have recently stopped taking anti inflammatory drugs for joint pain and tried this product. Like other supplements, it takes a week or so before you can feel the effects. After that time, I could feel a difference in my pain and mobility level. It reaaly helps and is a much safer way to address inflammation.

Browse Similar Items
Health Concerns > Inflammation & Pain
Health Concerns > Inflammation & Pain > Chronic Pain

Need Assistance?
Click here to Contact Us. We can help suggest the best product for your needs!

About Rockwell Nutrition

Nutrition Consultations
with Julie Haugen,
MS,RD,LN/D



Sitemap
Copyright RockwellNutrition.com. All Rights Reserved.