HMF Replete is a highly concentrated probiotic formula in sachets which provides strains of proprietary human-sourced Lactobacillus acidophilus, Lactobacillus salivarius, Bifidobacterium bifidum and Bifidobacterium animalis subsp. lactis along with fructooligosaccharides (FOS) in high concentrations to ensure rapid establishment and dominance of probiotic cultures in the gastrointestinal tract.
HMF Replete is the highest potency HMF product containing a minimum of 150 billion CFU of L. acidophilus, L. salivarius, B. bifidum, B. animalis lactis, and in each packet. It also includes prebiotic oligosaccharides to stimulate growth of beneficial bacteria in the digestive system. Each of the different strains attach in different areas of the epithelial tissue in the intestinal tract (small and large intestines).
High concentrations in these sachets are to ensure rapid establishment and dominance of probiotic cultures in the gastrointestinal tract, especially during and following antibiotic therapy, chemotherapy and radiation therapy. Major imbalances of friendly bacteria may result in severe abdominal discomfort, extreme fatigue and yeast infections. This probiotic is a microbial replacement program for the gastrointestinal tract intended for 7 to 14 days depending on the level of need.
Supplementation of Lactobacilli and Bifidobacteria will crowd out unwanted bacteria by repopulating the gastrointestinal tract. Lactobacillus salivarius, which triggers an anti-inflammatory response, has been demonstrated to be beneficial in acute and severe intestinal disturbances, dysbiosis, and inflammatory bowel diseases such as Irritable Bowel Syndrome, Crohn's and ulcerative colitis. This product can be used in autoimmune conditions such as multiple sclerosis, lupus and rheumatoid arthritis, but keep in mind that the probiotics activate the immune system so you may want to try a lesser potency probiotic from the HMF probiotic line before taking this product so not to over-stimulate the immune system ( consult the nutritionist here for guidance).
Pharmax and GENESTRA BRANDS™ are probiotic science and innovation leaders, with over 20+ years of proven experience and an ongoing commitment to incorporate the safest and most effective strains that reflect the latest evidence-based research from human trials. Their probiotics are human-sourced strains, proven in human clinical trials and cover a comprehensive product range. These Human Micro Flora (HMF) are human-derived strains and are the original product line of their kind in North America. Most other probiotics are made from animal or dairy strains and may not adhere as well to the human gastrointestinal tract.
Recommended Adult Dosage: In a glass, add water to ˝ sachet of HMF Replete and mix. Take once daily with a meal, or as recommended by your healthcare practitioner.
Total potency per sachet may be up to 170 billion CFU's.
Guaranteed to contain no added wheat, starch, gluten, soy, artificial coloring or flavoring, antimicrobial preservatives, dairy or animal products. Ideal for vegans.
If you have an immune compromised condition, do not use. If you are experiencing nausea, fever, vomiting, bloody diarrhea or severe abdominal pain, consult your healthcare practitioner prior to use. If symptoms of digestive upset occur, worsen or persist beyond three days, discontinue use and consult your healthcare practitioner.
Quality Assurance Safety-sealed for your protection and for product freshness. Do not use if sachet is opened. Refrigeration of this product is recommended to prolong shelf life. Label claim will be met if unrefrigerated up to three months.
Before you order HMF Probiotics, read this important information on shipping, storage, and clinical research here.
Additional product info:
The human microbiota influences the state of health of our gastrointestinal tract. Although much of our initial microbiota is adopted from our mothers, its final composition and diversity is determined by environmental factors. Extensive experimental and clinical evidence indicates that the westernized diet, rich in animal products and low in complex carbohydrates, plus the overuse of antibiotics and underuse of breastfeeding, leads to a heightened inflammatory potential of unfavorable microbiota (1).
Other factors such as environmental pollutants and stress may also alter the fragile intestinal ecosystem equilibrium, which can lead to physiological changes in the intestinal environment, disrupting the functions of the gut microbiota. Autoimmune, allergic and bacterial infections have all been associated to gut dysbiosis (8). Bifidobacterium bifidum and Lactobacillus lactis are found more commonly in the composition of the intestinal flora of non-allergic children (6),(7). In addition, HMF Replete is indicated for dysbiosis(8), and symptoms associated with irritable bowel syndrome (IBS) (2) which has also been shown in human double-blind, placebo-controlled clinical studies, at a core consortium of 25 billion CFU to:
• Reduce the risk of Clostridium difficile associated diarrhea in hospitalized patients (5)
• Significantly improved the Symptom Severity Score of patients suffering from irritable bowel syndrome (IBS) and scores for quality of life, days with pain and satisfaction with bowel habit compared to placebo, when taken for 8 weeks (2)
• Daily administration of Lactobacillus salivarius to healthy adults has shown to improve gut microbiota and different parameters related to immune response (9).
HMF Replete will crowd out yeast and other undesirable organisms which result from use of antibiotics, chemotherapy, oral contraceptives, and hormone replacement therapy. Also helpful for chronic parasitic and fungal infections as well as Candida overgrowth.
Take 1 packet daily (1/2 packet twice daily) after meal or snack, mixed in water or in smoothie or off the spoon for 7-14 days.
During and Post-antibiotic therapy
Acute intestinal upset
Candidiasis (as a follow up after no FOS probiotic has been used)
Digestive disturbances (bloating, gas)
Chronic Fatigue Syndrome
Bowel problems (constipation, diarrhea, IBS)
Take 1/2 packet daily after meal or snack, mixed in water or in smoothie or off the spoon.
Stressful life style
Digestive problems (bloating, gas)
Excessive alcohol consumption
Bowel problems (constipation, diarrhea, IBS)
Chronic Fatigue Syndrome
Candidiasis (as a follow up after no FOS probiotic has been used)
Greer JB, O'Keefe SJ. Microbial induction of immunity, inflammation, and cancer. Front Physiol. 2011 Jan 26;1:168
Williams EA, Stimpson J, Wang D, Plummer S, Garaiova I, Barker ME, Corfe BM. “Clinical trial: a multistrain probiotic preparation significantly reduces the symptoms of irritable bowel syndrome in a double-blind placebo-controlled trial.” Alimentary Pharmacology & Therapeutics. 2008. 29(1):97-103.
Plummer SF, Garaiova I, Sarvotharn T, Cottrell SL, LeScouiller S, Weaver MA et al. Effects of probiotics on the composition of the intestitinal microbiota following antibiotic therapy. Int J Antimicrob Agents. 2005; 26(1):69-74.
Madden JA, Plummer SF, Tang J, Garaiova I, Plummer NT, Herbison T, et al. Effects of probiotics on preventing disruption of the intestinal microflora following antibiotic therapy: a double-blind, placebo-controlled pilot study. Int Immunopharmacol. 2005; (6): 1091-7.
5. Plummer, S., Weaver, M.A., Harris, J.C., Dee, P. and Hunter, J. “ Clostridium difficile pilot study: effects of probiotics supplementation on the incidence of C.difficile diarrhea.” International Microbiology. 2004; 7(1):59-62.
Ozdemir O. Various effects of different probiotic strains in allergic disorders: an update from laboratory and clinical data. Clin Exp Immunol. 2010 Jun;160(3):295-304.
Kim JY, Kwon JH, Ahn SH, Lee SI, Han YS, Choi YO, Lee SY, Ahn KM, Ji GE. Effect of probiotic mix (Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus acidophilus) in the primary prevention of eczema: a double-blind, randomized, placebo-controlled trial. Pediatr Allergy Immunol. 2010 Mar;21(2 Pt 2):e386-93.
Prakash S, Rodes L, Coussa-Charley M, Tomaro-Duchesneau C. Gut microbiota: next frontier in understanding human health and development of biotherapeutics. Biologics. 2011;5:71-86.
Sierra S, Lara-Villoslada F, Sempere L, Olivares M, Boza J, Xaus J. Intestinal and immunological effects of daily oral administration of Lactobacillus salivarius CECT5713 to healthy adults. Anaerobe. 2010 Jun;16(3):195-200.
Summer Shipping/Delivery Schedule JUN - SEPT.
(Saturday delivery is not available)
(Orders received after 1pm EST will be processed the next day)
Monday by 1pm EST
Ground shipping - delivery on Thursday
2nd day shipping - delivery on Wednesday
Overnight - delivery on Tuesday
Tuesday by 1pm EST
Ground shipping - delivery on Friday
2nd day shipping - delivery on Thursday
Overnight - delivery on Wednesday
Wednesday by 1pm EST - only 2nd day & overnight orders will be processed.
Orders received after 1pm or which have ground shipping, will be held until the following Monday.
2nd day - delivery on Friday
Overnight - delivery on Thursday
Thursday by 1pm EST - only Overnight orders will be processed.
Orders received after 1pm or which have ground shipping or 2nd day, will be held until the following Monday.
Overnight - delivery Friday
Friday - ALL HEAT SENSITIVE ORDERS RECEIVED ON FRIDAY WILL BE HELD FOR SHIPPING UNTIL THE FOLLOWING MONDAY.
Should I request a cold pack? From June-Sept, we recommend requesting an cold pack at check out as the cold pack helps keep the interior package temperature cooler during the hot travel months. Between Sept - May requesting a cold pack is optional, but you may want to do so if shipping to a hot climate (over 85 degrees F).
After extensive product testing with the freeze drying technology performed by Genestra, it was concluded that the cold pack did not make a difference during shipping since the product potency was still well over 100% label claim when shipped with ice or no ice. The manufacturer states that it is less necessary to ship the HMF products with an cold pack for these reasons: 1. Genestra has added in >40% more probiotic than what the label guarantees per bottle. For example, HMF Forte is guaranteed to have 10 billion CFU's per serving, but there are 18-20 billion present at time of manufacturing and it is kept frozen until shipping. 2. The probiotics to last up to 3 months at room temperature holding their GUARANTEED minimum potency on label! 3. You will receive your HMF probiotic directly from the manufacturer or our distributor in about 3-5 days. This product is very fresh and has not been sitting around on our shelves.
How do I travel with my HMF probiotics? We highly recommend you take your probiotics with you on all trips and vacations since their potency will last for up to 3 months at room temperature un-refrigerated. But, when possible and if convenient, we recommend you store your probiotics in the freezer or refrigerator, especially if you plan to preserve freshness of your product for months or years.
Reviewed by coleen handlon-shaull from detroit, michigan.
great product. using it to ferment coconut milk into a probiotic coconut cream. Sour and delicious. Thank you for the great probiotic.
hmf replete probiotic
Reviewed by sha from shrewsbury.
has changed my life. I take it everyday,and if i miss a day my body feels it. I recommend it to everyone.
HMF Replete probiotic
Reviewed by dwolfl from Maine.
Excellent product, the first probiotic I ever took as prescribed by my ND. Though a bit pricey, it supports digestion and immune health and is well worth the price.
HMF - For Antibiotic Use
Reviewed by LCEngel from California.
I always turn to HMF after using antibiotics. It is a great product and always helps recover gut health effectively.
Reviewed by Janice from Lansing, NY.
HMF Replete is hands doen the best probiotic for reestablishing gut microbial status after illness. Works quickly and thoroughly with a noticeable improvement in just a day or two. I always keep some in the refrigerator.
Reviewed by Linda from florida.
The product seems good enough though I won't really know if its working for another couple months. It would be easier if the packages were divided in 2 as I am taking one packet twice a day. Also was annoyed that I paid for the cooler for them to be shipped and the cooler only held 1/3 of what I bought so the others were put in a box with the cooler packs. I do like that its a powder and freeze dried- was easier for me to travel with.
Reviewed by Jackie from Madison, WI.
I really try to avoid antibiotics and for those times when it seems absolutely necessary, I rely on Replete Probiotic to quickly re-establish my flora.
HMF Replete Probiotic by Genestra
Reviewed by Lorene Elliott from 360 SugarTree Rd. Warrensville, NC 38693.
I have used this product for several years and it works very well. I am so glad that I can obtain it from you.
Fixed thrush for me an my nursing baby
Reviewed by Tina M. from Phoenixville, PA.
Thank you, your product was great & helped to clear a thrush issue I was having with nursing my infant who also had thrush. I am happy to say I don't need any further assistance!
Reviewed by builder from Michigan.
Didn't like the taste - haven't yet decided if it is doing any good.
Helped to vanquish c.diff
Reviewed by Catherine B from Saint Charles, IL.
After 2 relapses of c.diff, our daughter followed her 3rd round of antibiotics with 2 weeks of HMF Replete and then 2 weeks of HMF intensive. So far the c.diff has not come back. (Praise God!)
Reviewed by Carlin Ellison from San Francisco.
After finding the right dosages for me, I'm very happy with this product. With the 1/2 sachet I started on, I had gastrointestinal problems, but when I tried 1/4 packet, it was fine. Gradually I increased it to 1/2 sachet, and that is fine now. It's easy and pleasant to take, and I believe I can feel it working (in a very subtle way).
Reviewed by Ginny from NY.
The acupuncturist, ND and MD all told me to use this product when I was first diagnosed with a leaky gut. I have celiac and my GI tract was a MESS! It works well. No bloating, if you dose gradually. Half a sachet is plenty!
HMF Replete - Do you suffer from bloating?
Reviewed by JL from Canada.
People who take this product and suffer from bloating or stomach pains should take the product Packets (Sachets) in smaller steps to allow your stomach to get used to the effects of the HMF product. Heres a routine that I recommend when starting this product. This is only my opinion, but has worked out extremely well.
First Packet take 1/4 serving size once a day (4 Days). Second Packet take 1/4 Serving size twice a day (2 Days). Remaining Packets take 1/2 Serving size twice a day (5 Days). If you break it up through 2 servings a day, it will lessen the abdominal pains and still allow the effect of the HMF to full penetrate your system. This is probably the best product i've used and recommended to anyone looking for a serious probiotic treatment.
Best of Luck :)
Worth the investment
Reviewed by RS from Oregon, US.
I love this product! You can definitely feel it working. I am debating using this as my regular probiotic as it works so much better than the "maintenance" products for me.
Reviewed by TB from Cleveland.
suggested by our allergist, this has worked well for our daughter. She's not thrilled w the taste, but she's a trooper. Has helped significantly w chronic constipation.
HMF Replete by Genestra
Reviewed by erika from Dallas, TX.
This probiotic did not work out very well for our son. He was very gassy, his tummy was bloated and he was uncomfortable.
I think the product is too sweet, plus i am not crazy about the maltodextrin.
We however, believe Genestra is a good brand, so we switched to HMF Intensive. That one did work out well for us.
HMF Replete Probiotic by Genestra (7 sachets)
Reviewed by eagle4102 from Jacksonville ,Fl.
Great product , ok Price! I thought since you were located in Florida, That it would ship from Florida?....... wrong. [Actually our website specifies where we ship from: Where are your products shipped from: Most products are shipped from Bedford, NH (UPS), or E. Windsor, CT. (Fedex) Expect up to 5 business days for UPS/Fedex Ground if you live on the West coast, and as little as two days if you live in the Northeast. Pharmax products are usually shipped from Wooddale, IL. (UPS)]
Reviewed by Trish from Vermont.
I am so happy to find a probiotic which such a high count of beneficial flora. It has been working well for my son who has intestinal issues. I wish they would make this same product without sugar (FOS). They make others without FOS but they don't have the high HMF count as the others.
no trips to the doctor
Reviewed by Terra from Huntington Indiana.
Last year my 3 kids had reoccuring strep throat and other infections. I started them on this in the Spring and haven't had to take them to the doctor since. We have NEVER gone this long without some type of infection or illness in my house.