These packets are designed to assist the body in using fat for fuel and to help support healthy insulin, cortisol and energy levels. They are a great boost for any weight loss program.
Each packet contains:
2 Carnitine Synergy™ capsules
2 EndoTrim™ capsules
1 Thermo-EFx™ capsule
Weight Loss Support Packets are designed to help the body:
Vanadium (TRAACS® Vanadium Nicotinate Glycinate Chelate) 100 mcg
Other Ingredients: Microcrystalline cellulose, vegetable stearate, rice flour.
This product does not contain: wheat, yeast, soy, gluten, eggs, dairy, corn, artificial colors, flavors, sugars, or preservatives.
Carnitine Synergy Serving Size: 4 Capsules Amount per Serving:
L-Carnitine (from L-Carnitine Tartrate) 1600 mg
Acetyl-L-Carnitine 400 mg
Other Ingredients: Stearates (vegetable source), microcrystalline cellulose, silicon dioide.
This product does not contain: wheat, yeast, soy protein, gluten, eggs, dairy, corn, artificial colors, flavors, sugars, or preservatives. Carnitine is the purest and highest quality form of carnitine available.
Other Ingredients: Microcrystalline cellulose, vegetable stearate
Caution: This product contains Naringin, which is a flavonoid found in grapefruit. Grapefruit affects the activities of many drugs, with potentially serious effects. Interactions with various drugs (prescription or over-the-counter) can occur when using any part or form of grapefruit, including grapefruit juice or peel. Patients taking prescription drugs who are considering using a product that contains grapefruit (or a product that contains naringin) are encouraged to talk with their healthcare providers or pharmacists. A number of drugs that are known to be affected by the naringin in grapefruit include calcium channel blockers, estrogen, sedatives, medications for high blood pressure, allergies, AIDS, and cholesterol-lowering drugs.
Store In A Cool, Dry Place. Keep Out Of Reach Of Children.
Coleus forskohli and these medication contraindications:
Theoretically, concomitant use of forskolin and anticoagulant or antiplatelet agents might increase the risk of bruising and bleeding. There is some evidence forskolin can inhibit platelet aggregation and adhesion. Some anticoagulant and antiplatelet drugs include abciximab (ReoPro), anagrelide (Agrylin), antithrombin III (Thrombate III), ardeparin (Normiflo), cilostazol (Pletal), clopidogrel (Plavix), dalteparin (Fragmin), danaparoid (Orgaran), dicumarol, dipyridamole (Persantine), enoxaparin (Lovenox), eptifibatide (Integrilin), heparin, lepirudin (Refludan), tirofiban (Aggrastat), and warfarin (Coumadin).
CALCIUM CHANNEL BLOCKERS: Using forskolin with calcium channel blockers such as verapamil (Calan, Covera-HS, Verelan), nifedipine (Procardia), and diltiazem (Cardizem, Dilacor, Tiazac) might cause additive coronary vasodilatory effects.
NITRATES: Using forskolin with nitrates such as nitroglycerin (Nitro-Bid, Nitro-Dur, Nitrostat) and isosorbide (Imdur, Isordil, Sorbitrate) might cause additive coronary vasodilatory effects.
SURGERY: Forskolin has antiplatelet effects. Forskolin might cause excessive bleeding if used perioperatively. Discontinue forskolin at least 2 weeks before elective surgical procedures.
EndoTrim by Designs For Health
EndoTrim is a comprehensive endocrine balancing formula designed to promote optimal insulin, leptin and cortisol balance. This formula is for anyone wishing to improve body composition.
Decrease body fat
Increase lean muscle
Glucose and insulin control
Decrease food cravings
EndoTrim contains the non-stimulating American ginseng for costisol balance. Banaba, chromium and vanadium are included to enhance glucose control and insulin performance. ForsLean (Coleus forskohli), Garcinia cambogia, and green tea extract promote lean body mass through ergogenic activity. Activated B vitamins, magnesium and L-carnitine provide nutrients for optimal mitochondrial function and metabolism. N-acetyl-tyrosine supports thyroid function and proper catecholamine balance. The addition of GABA, along with magnesium, provides an element of craving control to this unique product. These nutrients also help keep us calm when stressed.
Carnitine Synergy by Designs For Health
Fuels the mitrochondria for fat burning. Without Carnitine fats cannot be burned for energy. Without energy, cells become weak or die. Because of this, optimizing Carnitine levels has been found to have dramatic benefits for low energy, obesity, chronic fatigue, immune deficiency conditions, and elevated cholesterol and triglycerides. Controlled trials have demonstrated that Carnitine increases weight loss by promoting optimal fat burning by the mitochondria. Carnitine also helps promote heart health, cholesterol lowering, sports endurance, and helps relieve chronic fatigue. Acetyl-L-Carnitine is also contained in Carnitine Synergy and has unique brain health enhancing properties. Carnitine Synergy is the only product of its kind combining both of these valuable forms of Carnitine into one capsule.
Benefits of Carnitine Synergy:
Increases Fat Burning
Increases Energy Levels
Lowers Cholesterol and Triglycerides
Promotes Heart Health
Helps Produce More Energy to Exercise and Increases Exercise Endurance and Performance
Reduces Food Cravings
Promotes Healthy Circulation
Promotes Liver Health
Counters the Side Effects of Medications such as Valproate, Adriamycin, and AZT
Enhances Brain Function
Quickly Improves mental Focus and Energy
Enhances Short- and Long-Term Memory
Thermo-EFx™ is designed to support healthy weight loss by helping to increase the body’s metabolic rate safely without causing any stimulant-associated side effects often seen with other weight reduction formulas.
Advantra Z® is a bitter orange extract (Citrus aurantium L.) which has been shown to increase thermogenesis and basal metabolic rate (BMR).1 It contains a family of adrenergic amines, agents that mimic the actions of the sympathetic nervous system – acting like the neurotransmitter epinephrine (adrenaline) – but differ in their effects (no stimulant- type side effects). These amines help to stimulate metabolic processes while increasing lipolysis, the breakdown of fat. They also help to increase lean muscle mass by encouraging the uptake of amino acids into muscle tissue, and may have mild appetite-suppressant effects.1,2
Advantra Z® is the only bitter orange extract standardized and purified to contain primarily naturally occurring p-synephrine while having negligible amounts of m-synephrine. Unlike p-synephrine, m-synephrine is undesirable because it increases blood pressure and heart rate by acting on beta-1 and beta-2 adrenergic receptors.3 Thus, p-synephrine is an analog of adrenaline but does not have the side effects associated with adrenaline. It does not act on beta-1 and beta-2, but rather on the beta-3 adrenergic receptors that induce lipolysis and result in reduced food intake and improved insulin sensitivity, glycemic control and lipid profiles.3 Many products on the market contain synthetic m-synephrine and often do not specify what kind of synephrine they contain. Certain types of bitter orange do not control the levels of m-synephrine.
Thermo-EFx benefits may include:
• Increased BMR: a potential additive effect from Advantra Z® + naringin + hesperidin (may increase BMR by 17%).9 EGCg may further increase and prolong the elevated BMR.6
• Improved insulin sensitivity (green tea8)
• Reduced glucose absorption (green tea10)
• Appetite control (green tea11, Advantra Z®2)
• Improved mood: from more stable adrenaline and dopamine levels (green tea10)
• Additional health benefits: antioxidant (green tea10, cardiovascular and brain health support (green tea10), compen- sation for adrenaline insufficiency (green tea6, Advantra Z®12)
• None of the typical side effects of stimulants: will not cause anxiety or insomnia or increase heart rate or blood pressure3
Naringin (Citrus grandis osbeck) and hesperidin are antioxidant- rich bioflavonoids found in grapefruit and many other citrus fruits. Research shows that, when combined, these two bioflavonoids increased the thermogenic effects of p-synephrine (contained in Advantra Z®). Together, naringin and hesperidin work to enhance the expression of adiponectin, the protein hormone secreted by adipocytes (fat cells) which helps to regulate lipid and glucose metabolism.4,5
Green Tea Extract (decaffeinated and standardized to 45% EGCg [epigallocatechin gallate]). EGCg has been shown to stimulate thermogenesis by enhancing basal metabolic rate. It works by inhibiting catechol-O-methyl-transferase (COMT), an enzyme that metabolizes norepinephrine. Thus, it extends the half life of adrenaline and p-synephrine, which stimulate the fat release from fat cells.6,7 Green tea also helps to increase insulin sensitivity and reduce glucose absorption.8
The green tea extract in Thermo-EFx™ is decaffeinated, which makes this formula suitable for individuals with sensitivity to caffeine. However, those who consume caffeine regularly can do so based on their particular health status, personal tolerance and advice from their health care practitioner. The addition of caffeine to green tea was shown in studies to increase thermogenesis and metabolic rate more than green tea alone.6
• Caffeine can be added to this regimen from coffee or other sources as discussed above. Green tea (caffeinated or not) can also be consumed when taking this formula to further enhance thermogenesis based on individual tolerance.6
1. Seaweed carotenoid, fucoxanthin, as a multi-functional nutrient. Maeda H, Tsukui T, Sashima T, Hosokawa M, Miyashita K. Asia Pac J Clin Nutr. 2008;17 Suppl 1:196-9. PMID:18296336 http://www.ncbi.nlm.nih.gov/pubmed/18296336
2. Fucoxanthin and its metabolite, fucoxanthinol, suppress adipocyte differentiation in 3T3-L1 cells. Maeda H, Hosokawa M, Sashima T, Takahashi N, Kawada T, Miyashita K. Int J Mol Med. 2006 Jul;18(1):147-52. PMID:16786166http://www.ncbi.nlm.nih.gov/pubmed/16786166
3. The hypoglycemic effects of hesperidin and naringin are partly mediated by hepatic glucose-regulating enzymes in C57BL/KsJ-db/db mice. Jung UJ, Lee MK, Jeong KS, Choi MS. J Nutr. 2004 Oct;134(10):2499-503. PMID:15465737http://www.ncbi.nlm.nih.gov/pubmed/15465737
4. Naringenin and hesperetin, two flavonoids derived from Citrus aurantium up-regulate transcription of adiponectin. Liu L, Shan S, Zhang K, Ning ZQ, Lu XP, Cheng YY. Phytother Res. 2008 Oct;22(10):1400-3. doi: 10.1002/ptr.2504. PMID:18690615 http://www.ncbi.nlm.nih.gov/pubmed/18690615
5. The effects of Xanthigen in the weight management of obese premenopausal women with non-alcoholic fatty liver disease and normal liver fat. Abidov M, Ramazanov Z, Seifulla R, Grachev S. Diabetes Obes Metab. 2010 Jan;12(1):72-81. doi: 10.1111/j.1463-1326.2009.01132.x. Epub 2009 Oct 13. PMID:19840063 http://www.ncbi.nlm.nih.gov/pubmed/19840063
6. Xanthigen suppresses preadipocyte differentiation and adipogenesis through down-regulation of PPARγ and C/EBPs and modulation of SIRT-1, AMPK, and FoxO pathways. Lai CS, Tsai ML, Badmaev V, Jimenez M, Ho CT, Pan MH. J Agric Food Chem. 2012 Feb 1;60(4):1094-101. doi: 10.1021/jf204862d. Epub 2012 Jan 17. PMID:22224971
7. Fucoxanthin-rich seaweed extract suppresses body weight gain and improves lipid metabolism in high- fat-fed C57BL/6J mice. Jeon SM, Kim HJ, Woo MN, Lee MK, Shin YC, Park YB, Choi MS. Biotechnol J. 2010 Sep;5(9):961-9. doi: 10.1002/biot.201000215.PMID:20845386 http://www.ncbi.nlm.nih.gov/pubmed/20845386
8. Effect of medium-chain triacylglycerols on anti-obesity effect of fucoxanthin. Maeda H, Hosokawa M, Sashima T, Funayama K, Miyashita K. J Oleo Sci. 2007;56(12):615-21. PMID:17992001 http://www.ncbi.nlm.nih.gov/pubmed/17992001
9. Dietary combination of fucoxanthin and fish oil attenuates the weight gain of white adipose tissue and decreases blood glucose in obese/diabetic KK-Ay mice. Maeda H, Hosokawa M, Sashima T, Miyashita K. J Agric Food Chem. 2007 Sep 19;55(19):7701-6. Epub 2007 Aug 23.PMID:17715888 http://www.ncbi.nlm.nih.gov/pubmed/17715888
10. Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues. Maeda H, Hosokawa M, Sashima T, Funayama K, Miyashita K. Biochem Biophys Res Commun. 2005 Jul 1;332(2):392-7.PMID:15896707 http://www.ncbi.nlm.nih.gov/pubmed/15896707
11. The allenic carotenoid fucoxanthin, a novel marine nutraceutical from brown seaweeds. Miyashita K, Nishikawa S, Beppu F, Tsukui T, Abe M, Hosokawa M. J Sci Food Agric. 2011 May;91(7):1166-74. doi: 10.1002/jsfa.4353. Epub 2011 Mar 23. Review.PMID:21433011 http://www.ncbi.nlm.nih.gov/pubmed/21433011
12. Effects of p-synephrine alone and in combination with selected bioflavonoids on resting metabolism, blood pressure, heart rate and self-reported mood changes. Stohs SJ, Preuss HG, Keith SC, Keith PL, Miller H, Kaats GR. Int J Med Sci. 2011 Apr 28;8(4):295-301.PMID:21537493 http://www.ncbi.nlm.nih.gov/pubmed/21537493
13. A review of the human clinical studies involving Citrus aurantium (bitter orange) extract and its primary protoalkaloid p-synephrine. Stohs SJ, Preuss HG, Shara M. Int J Med Sci. 2012;9(7):527-38. Epub 2012 Aug 29.PMID: 22991491 http://www.ncbi.nlm.nih.gov/pubmed/22991491
14. Exactly which synephrine alkaloids does Citrus aurantium (bitter orange) contain? Allison DB, Cutter G, Poehlman ET, Moore DR, Barnes S. Int J Obes (Lond). 2005 Apr;29(4):443-6. PMID:15700046 http://www.ncbi.nlm.nih.gov/pubmed/15700046
15. A review of the receptor-binding properties of p-synephrine as related to its pharmacological effects. Stohs SJ, Preuss HG, Shara M. Oxid Med Cell Longev. 2011;2011:482973. doi: 10.1155/2011/482973. Epub 2011 Aug 1. Review. PMID:21904645 http://www.ncbi.nlm.nih.gov/pubmed/21904645
16. The safety of Citrus aurantium (bitter orange) and its primary protoalkaloid p-synephrine. Stohs SJ, Preuss HG, Shara M. Phytother Res. 2011 Oct;25(10):1421-8. doi: 10.1002/ptr.3490. Epub 2011 Apr 8. Review.PMID:21480414http://www.ncbi.nlm.nih.gov/pubmed/21480414
17. Citrus aurantium and synephrine alkaloids in the treatment of overweight and obesity: an update. Haaz S, Fontaine KR, Cutter G, Limdi N, Perumean-Chaney S, Allison DB. Obes Rev. 2006 Feb;7(1):79-88. Review.PMID:16436104 http://www.ncbi.nlm.nih.gov/pubmed/16436104
18. The effects of catechin rich teas and caffeine on energy expenditure and fat oxidation: a meta-analysis. Hursel R, Viechtbauer W, Dulloo AG, Tremblay A, Tappy L, Rumpler W, Westerterp-Plantenga MS. Obes Rev. 2011 Jul;12(7):e573-81. doi: 10.1111/j.1467-789X.2011.00862.x. Epub 2011 Mar 2. Review. PMID: 21366839 http://www.ncbi.nlm.nih.gov/pubmed/21366839
19. Health-promoting effects of green tea. Suzuki Y, Miyoshi N, Isemura M. Proc Jpn Acad Ser B Phys Biol Sci. 2012;88(3):88-101. Review. PMID: 22450537 http://www.ncbi.nlm.nih.gov/pubmed/22450537
20. Weight control and prevention of metabolic syndrome by green tea. Sae-tan S, Grove KA, Lambert JD. Pharmacol Res. 2011 Aug;64(2):146-54. doi: 10.1016/j.phrs.2010.12.013. Epub 2010 Dec 28. Review.PMID:21193040http://www.ncbi.nlm.nih.gov/pubmed/21193040
21. Green tea extract reduces blood pressure, inflammatory biomarkers, and oxidative stress and improves parameters associated with insulin resistance in obese, hypertensive patients. Bogdanski P, Suliburska J, Szulinska M, Stepien M, Pupek-Musialik D, Jablecka A. Nutr Res. 2012 Jun;32(6):421-7. doi: 10.1016/j.nutres.2012.05.007. Epub 2012 Jun 20.PMID:22749178 http://www.ncbi.nlm.nih.gov/pubmed/22749178
22. Does supplementation with green tea extract improve insulin resistance in obese type 2 diabetics? A randomized, double-blind, and placebo-controlled clinical trial. Hsu CH, Liao YL, Lin SC, Tsai TH, Huang CJ, Chou P. Altern Med Rev. 2011 Jun;16(2):157-63. PMID:21649457 http://www.ncbi.nlm.nih.gov/pubmed/21649457
23. Effects of dietary supplementation with the green tea polyphenol epigallocatechin-3-gallate on insulin resistance and associated metabolic risk factors: randomized controlled trial. Brown AL, Lane J, Coverly J, Stocks J, Jackson S, Stephen A, Bluck L, Coward A, Hendrickx H. Br J Nutr. 2009 Mar;101(6):886-94. doi: 10.1017/S0007114508047727. Epub 2008 Aug 19.PMID:18710606 http://www.ncbi.nlm.nih.gov/pubmed/18710606
24. Does green tea affect postprandial glucose, insulin and satiety in healthy subjects: a randomized controlled trial. Josic J, Olsson AT, Wickeberg J, Lindstedt S, Hlebowicz J. Nutr J. 2010 Nov 30;9:63. doi: 10.1186/1475-2891-9-63. PMID:21118565 http://www.ncbi.nlm.nih.gov/pubmed/21118565
25. Naringin supplementation lowers plasma lipids and enhances erythrocyte antioxidant enzyme activities in hypercholesterolemic subjects. Jung UJ, Kim HJ, Lee JS, Lee MK, Kim HO, Park EJ, Kim HK, Jeong TS, Choi MS. Clin Nutr. 2003 Dec;22(6):561-8. PMID: 14613759 http://www.ncbi.nlm.nih.gov/pubmed/14613759
26. Fucoxantin: a treasure from the sea. D'Orazio N, Gemello E, Gammone MA, de Girolamo M, Ficoneri C, Riccioni G. Mar Drugs. 2012 Mar;10(3):604-16. doi: 10.3390/md10030604. Epub 2012 Mar 7. PMID:22611357http://www.ncbi.nlm.nih.gov/pubmed/22611357
27. Implication of cyclic nucleotide phosphodiesterase inhibition in the vasorelaxant activity of the citrus- fruits flavonoid (+/-)-naringenin. Orallo F, Camiña M, Alvarez E, Basaran H, Lugnier C. Planta Med. 2005 Feb;71(2):99-107. PMID:15729616 http://www.ncbi.nlm.nih.gov/pubmed/15729616
28. Citrus flavonoids and lipid metabolism. Assini JM, Mulvihill EE, Huff MW. Curr Opin Lipidol. 2013 Feb;24(1):34-40. doi: 10.1097/MOL.0b013e32835c07fd.PMID: 23254473 http://www.ncbi.nlm.nih.gov/pubmed/23254473
7/24/2012 Weight Loss Support Packets by Designs For Health (DFH)5
Reviewed by Nicole Jacomo from ft lauderdale, FL.
I like these very much. I feel well when I take them and I like the convenience of the packets.
6/14/2012 Weight Loss Support Packets by Designs For Health (DFH)5
Reviewed by Julia from DC Area.
Lost 12 pounds last year with increased exercise, reduced calories, and these packets. Results better than seen since age 40 - better fat loss, improved muscle tone. Long story - am now working to get weight back off. Began weight-loss routine with no packets; only moderate change. Started packets; already notice increased energy and hunger. Energy is great and view hunger as positive sign metabolism has picked up. Definitely like these packets and trust DFH more than anything over the counter.
Weight loss support packets
5/1/2012 Weight Loss Support Packets by Designs For Health (DFH)1
Reviewed by TH from New Hampshire.
Didn't seem to make any difference
Nutritionist Response: While these supplements may support a healthy way to optimize your metabolism and endocrine balance, they do not replace additional efforts need to promote weight loss, such as eating a healthy diet with slight caloric restriction and daily physical activity to support metabolism. Also, when taking these longer than one month, you should see better results than taking them for only one month. Julie Haugen, MS, RD, LN
Wt loss support
1/29/2010 Weight Loss Support Packets by Designs For Health (DFH)5
Reviewed by Becky from Tampa,fl.
Found that these packets kept my energy level up when on a VLCD (very low calorie diet)
Weight Loss Support
12/19/2009 Weight Loss Support Packets by Designs For Health (DFH)5