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Indole Plus by Rx Vitamins

200mg 60 tabs
Today's Price:
$34.00

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Indole Plus

Indole Plus provides the clinically recommended level of stabilized Indole-3-Carbinol supported by a unique delivery system that promotes a favorable pH environment at the receptor sites for maximum uptake and utilization of I3C. Indole Plus is manufactured in a state-of-the-art, humidity and temperature controlled facility and is assayed for activity and potency no fewer than 4 times during the manufacturing process. A plant based protein coating stabilizes the potency and activity of the I3C and protects it from the effects of oxidation.

For more information on Indole Plus, please consult with our nutritionist (see Contact Us) or your health practitioner.

Supplement Facts
Serving Size: 1 Tablet
Servings per Container: 60

Amount per Serving:
Indole 3-Carbinol 200 mg
L-Taurine (pharmaceutical grade amino acid) 20 mg
L-Glycine (pharmaceutical grade amino acid) 20 mg
Oxidase (5000 units/gram) 5 mg
Pyridoxal-5-phosphate 5 mg

    Suggested Use: As a dietary supplement, take two tablets in the morning, on an empty stomach or near-empty stomach or as recommended by your physician or health care professional. 

    Other Ingredients: Dicalcium phosphate, microcrystalline cellulose, silica and pharmaceutical glaze.

    What are some food sources of Indoles?
    Indole-3-carbinol is found in highest concentrations in broccoli, but is also found in other cruciferous vegetables, such as cauliflower, cabbage, and kale.
    References:
    1. Stoewsand GS. Bioactive organosulfur phytochemicals in Brassica oleracea vegetables?a review. Food Chem Toxicol 1995;33:537?43.
    2. Broadbent TA, Broadbent HS. The chemistry and pharmacology of indole-3-carbinol (indole-3-methanol) and 3-(methoxymethyl) indole. [Part I]. Curr Med Chem 1998;5:337?52.
    3. Broadbent TA, Broadbent HS. The chemistry and pharmacology of indole-3-carbinol (indole-3-methanol) and 3-(methoxymethyl) indole. [Part II]. Curr Med Chem 1998;5:469?91.
    4. Broadbent TA, Broadbent HS. The chemistry and pharmacology of indole-3-carbinol (indole-3-methanol) and 3-(methoxymethyl) indole. [Part I]. Curr Med Chem 1998;5:337?52.
    5. Broadbent TA, Broadbent HS. The chemistry and pharmacology of indole-3-carbinol (indole-3-methanol) and 3-(methoxymethyl) indole. [Part II]. Curr Med Chem 1998;5:469?91.
    6. Hecht SS. Chemoprevention of cancer by isothiocyanates, modifiers of carcinogen metabolism. J Nutr 1999;129:768S?74S [review].
    7. Verhoeven DT, Goldbohm RA, van Poppel G, et al. A review of mechanisms underlying anticarcinogenicity by brassica vegetables. Chem Biol Interact 1997;103:79?129 [review].
    8. Verhoeven DT, Goldbohm RA, van Poppel G, et al. Epidemiological studies on brassica vegetables and cancer risk. Cancer Epidemiol Biomarkers Prev 1996;5:733?48 [review].
    9. Talalay P, Zhang Y. Chemoprotection against cancer by isothiocyanates and glucosinolates. Biochem Soc Trans 1996;24:806?10.
    10. Maheo K, Morel F, Langouet S, et al. Inhibition of cytochromes P-450 and induction of glutathione S- transferases by sulforaphane in primary human and rat hepatocytes. Cancer Res 1997;57:3649?52.
    11. Barcelo S, Gardiner JM, Gescher A, Chipman JK. CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane. Carcinogenesis 1996;17:277?82.
    12. Plumb GW, Lambert N, Chambers SJ, et al. Are whole extracts and purified glucosinolates from cruciferous vegetables antioxidants? Free Radic Res 1996;25:75?86.
    13. Bradlow HL, Sepkovic DW, Telang NT, Osborne MP. Multifunctional aspects of the action of indole-3-carbinol as an antitumor agent. Ann N Y Acad Sci 1999;889:204?13.
    14. Bradlow HL, Sepkovic DW, Telang NT, Osborne MP. Indole-3-carbinol. A novel approach to breast cancer prevention. Ann N Y Acad Sci 1995;768:180?200.
    15. Bradlow HL, Sepkovic DW, Telang NT, Osborne MP. Multifunctional aspects of the action of indole-3-carbinol as an antitumor agent. Ann N Y Acad Sci 1999;889:204?13.
    16. Meng Q, Qi M, Chen DZ, et al. Suppression of breast cancer invasion and migration by indole-3-carbinol: associated with up-regulation of BRCA1 and E-cadherin/catenin complexes. J Mol Med 2000;78:155?65.
    17. Yuan F, Chen DZ, Liu K, et al. Anti-estrogenic activities of indole-3-carbinol in cervical cells: implication for prevention of cervical cancer. Anticancer Res 1999;19(3A):1673?80.
    18. Jin L, Qi M, Chen DZ, et al. Indole-3-carbinol prevents cervical cancer in human papilloma virus type 16 (HPV16) transgenic mice. Cancer Res 1999;59:3991?7.
    19. Oganesian A, Hendricks JD, Pereira CB, et al. Potency of dietary indole-3-carbinol as a promoter of aflatoxin B1-initiated hepatocarcinogenesis: results from a 9000 animal tumor study. Carcinogenesis 1999;20:453?8.
    20. Kim DJ, Han BS, Ahn B, et al. Enhancement by indole-3-carbinol of liver and thyroid gland neoplastic development in a rat medium-term multiorgan carcinogenesis model. Carcinogenesis 1997;18:377?81.
    21. Dashwood RH. Indole-3-carbinol: anticarcinogen or tumor promoter in brassica vegetables? Chem Biol Interact 1998;110:1?5. [review]
    22. Rosen CA, Woodson GE, Thompson JW, et al. Preliminary results of the use of indole-3-carbinol for recurrent respiratory papillomatosis. Otolaryngol Head Neck Surg 1998;118:810?5.
    23. Bell MC, Crowley-Nowick P, Bradlow HL, et al. Placebo-controlled trial of indole-3-carbinol in the treatment of CIN. Gynecol Oncol 2000;78:123?9.
    24. Michnovicz JJ. Increased estrogen 2-hydroxylation in obese women using oral indole-3-carbinol. Int J Obes Relat Metab Disord 1998;22:227?9.
    25. Bradlow HL, Michnovicz JJ, Halper M, et al. Long-term responses of women to indole-3-carbinol
    26. or a high fiber diet. Cancer Epidemiol Biomarkers Prev 1994;3:591?5.
    Manufacturer: Rx Vitamins
    SKU: 2520

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