Indole-3-Carbinol (I3C) is a phytochemical naturally occurring in cruciferous vegetables. Once ingested, stomach acid converts I3C to various active metabolites including diindolylmethane (DIM), which are absorbed into the bloodstream.
Promotes Breast, Cervical and Prostate Cell Health
Ingredients per vcapsule: Indole-3-carbinol 200 mg
Other ingredients: Hypo-allergenic plant fiber
Recommendations Pure Encapsulations recommends taking between 200 mg and 800 mg indole-3-carbinol per day, in divided doses, with meals. This formula requires refrigeration.
Are There Any Potential Side Effects Or Precautions? Not to be taken by pregnant or lactating women. I3C should also be avoided by those sensitive to cruciferous vegetables.
Are There Any Potential Drug Interactions? The conversion of I3C to its active metabolites requires stomach acid. Therefore, antacids, H2 blockers, and proton-pump inhibitors may impede its effectiveness.
What Is The Source? In nature, indole-3-carbinol can be found in cruciferous vegetables such as broccoli, brussels sprouts, cabbage, bok choy, cauliflower, and kale. Indole-3-Carbinol in supplement form is synthetically produced. Hypo-allergenic plant fiber is derived from pine cellulose.
Promotes Breast, Cervical and Prostate Cell Health: Indole-3-carbinol has been shown to promote healthy phase I cytochrome P450 detoxification enzymes and phase II detoxification enzymes such as glutathione S-transferase (GST). This enhances the liver's ability to process and eliminate harmful compounds. It has also been reported to act as a scavenger of free radicals. Additionally, indole-3-carbinol is believed to have other mechanisms contributing to healthy cellular support.