0 Items in Bag | Total: $0 USD
Contact Us
1.866.757.4500
Back To School
Recommended
Nutritionist favorites
Brands
BioGenesis
Designs For Health
Health Practitioner Brands
Other Brands
Health Concerns
Addiction Recovery
Adrenal Fatigue
Adult Attention Deficit
Allergies
Anti-Aging
Arthritis & Joint Support
Athlete's Foot
Autoimmune Diseases
Baby Health ages 0-2
Bariatric Surgery Nutrition
Blood Sugar Issues
Bone Health & Osteoporosis
Brain Health
Cancer
Candida & Yeast
Cardiovascular Support
Children's Health ages 2-12
Circulation Support
Cold and Flu Support
Detox & Cleansing
Digestive GI Health
Ear Support
Emotional Well Being
Energy & Fatigue
Eye Health
Food Poisoning
Gout
Headache
Healthy Seniors
Hepatitis C
Herpes
Hormone Balance
Immune Support
Inflammation & Pain
Kidney Health & Kidney Stones
Lyme Disease
Mens Health
Muscle Cramps
Nervous System Support
Oral Health
Pet Health
Respiratory Health
Skin, Hair & Nails
Sleep Support
Sports Nutrition
Systemic Lupus
Thyroid Hormone Support
Travel Sickness
Urinary Support
Weight Loss
Women's Health
Wound Healing
Supplement Categories
Amino Acids
Antioxidant Formulas
Aromatherapy
Calcium and Magnesium
Dairy Free
Enzymes
Face and Body Care
Fiber
Fish Oils
Herbal
Homeopathics
Minerals
Multivitamins
Osteo Support Formulas
Probiotics
Protein Powders
Vitamins
Whole Food Supplements
Food Categories
Edible Oils
Protein Bars
Sea Salt
Seeds
Backordered Items
Currently Unavailable
Whats New!
Recently Added
Face SPF 30 Cucumber 1.7 oz by COOLA Sun Care
Face SPF 30 Cucumber 1.7 oz by COOLA Sun Care
Rockwell Nutrition has gone GREEN!

More Information

Home > Magnesium Side Effects
 
Magnesium Side Effects
Exploring the Benefits and Side Effects of Calcium

Magnesium Side Effects


A healthy, balanced diet that includes fiber-rich foods like fruits, vegetables, and grains is a good source of vitamins and minerals such as magnesium. Dietary magnesium promotes health and does not pose a health risk. However, pharmacologic doses of magnesium such as those found in supplements can have adverse effects especially when taken in large amounts or when a health problem affects its use.

Upper Limits of Magnesium Intake

There is no upper limit for magnesium that comes from dietary sources; however, according to the Institute of Medicine, for magnesium supplements, one must take care to observe these tolerable upper limits for intake:

  • For children 1-3 years old – 65 mg/day
  • For children 4-8 years old – 110 mg/day
  • Older than 8 years to adulthood – 350 mg/day

Magnesium is therefore considered to be likely safe for most people when used correctly, in doses less than 350 mg/day for healthy adults.

Risks and Side Effects

Magnesium supplements may possibly be unsafe when taken in large doses or when used by people who have certain health problems.

Minor side effects of taking these supplements are common, and these include diarrhea and abdominal cramping, stomach upset, nausea, and vomiting.

Taking large doses of these supplements on a regular basis might cause a build-up of magnesium in the body, causing serious side effects like confusion, irregular heartbeats, low blood pressure, slowed breathing, coma, and death.

Special precautions and warnings are given to people who have kidney disease and kidney failure, since these conditions may cause failure to eliminate excess magnesium from the body even when these supplements are taken in regular doses. Although dietary magnesium may not harm them, taking extra magnesium can cause a build-up of these minerals to dangerous levels.

Another condition that requires precaution is for people who have heart blocks, a type of heart rhythm irregularity, since magnesium influences electrical conduction and contraction of the heart. People with other types of heart rate irregularities such as atrial fibrillation and bradycardia (excessively slow heart rate) should consult a doctor before taking magnesium supplements.

Aside from taking magnesium as a dietary supplement, people also take magnesium in the form of antacids to relieve indigestion or laxatives to relieve constipation. However, taking too much of these antacids and laxatives may also lead to magnesium toxicity.

Signs of magnesium toxicity may be similar to those of magnesium deficiency. These include irregular heartbeat, changes in mental status, loss of appetite, nausea, diarrhea, muscle weakness, extremely low blood pressure, and difficulty in breathing.

Drug Interactions

One must also be careful of the possible drug interactions between magnesium and these medications:

  • Some antibiotics (aminoglycosides) like amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), streptomycin, and tobramycin (Nebcin) interact with magnesium because these substances, like magnesium, affect the muscles.
  • Magnesium may reduce the absorption and the effects of quinolone antibiotics such as ciprofloxacin (Cipro), enoxacin (Penetrex), norfloxacin (Chibroxin, Noroxin), and sparfloxacin (Zagam). To avoid this interaction magnesium and antibiotics should not be taken together. One may take the antibiotics at least 2 hours before, or 4 to 6 hours after taking magnesium supplements.
  • Magnesium decreases the amount of tetracycline antibiotics absorbed in the stomach by attaching to them, thereby decreasing their effectiveness. To avoid this interaction one may take magnesium 2 hours before or 4 hours after taking these antibiotics: demeclocycline (Declomycin), minocycline (Minocin), and tetracycline (Achromycin).
  • Magnesium can also decrease how much bisphosphate is absorbed by the body, thereby reducing their effects. To avoid this interaction one must take bisphosphonate at least two hours before magnesium or later in the day. Examples of bisphosphonates are alendronate (Fosamax), etidronate (Didronel), risedronate (Actonel), and tiludronate (Skelid).
  • Medications for high blood pressure, specifically calcium channel blockers, when taken with magnesium, might cause the blood pressure to drop too low, since magnesium also reduces blood pressure. These include nifedipine (Adalat, Procardia), verapamil (Isoptin, Verelan), diltiazem (Cardizem), isradipine (DynaCirc), felodipine (Plendil), and amlodipine (Norvasc). Consult a doctor for advice on taking magnesium and these medications.
  • Taking magnesium along with muscle relaxants can increase the risk of side effects of these medications, since magnesium also relaxes the muscles. Some muscle relaxants include carisoprodol (Soma), pipecuronium (Arduan), atracurium (Tracrium), pancuronium (Pavulon), and succinylcholine (Anectine).
  • Some potassium-sparing diuretics or "water pills" can increase the levels of magnesium in the body, thus increasing the risk for toxicity. These "water pills" include amiloride (Midamor), spironolactone (Aldactone), and triamterene (Dyrenium).

Recommendations

The safest way to maintain normal magnesium levels in the body is to consume a healthy diet that includes magnesium-rich foods such as vegetables and grains. People who have a condition that increases their risk for magnesium deficiency may prevent or treat the deficiency by taking supplemental doses of magnesium in the form of tablets, capsules, powders, or liquids.

Magnesium supplements in doses up to 350 mg/day in adults are likely to be safe. However, taking large doses increases one’s risk for side effects and toxicity. Certain health conditions and medications warrant medical advice regarding supplemental intake of magnesium, since these may also increase one’s risk for undesirable side effects.

References

  1. Find a Vitamin or Supplement: Magnesium. WebMD. http://www.webmd.com/vitamins-supplements/ingredientmono-998-MAGNESIUM.aspx?activeIngredientId=998&activeIngredientName=MAGNESIUM
  2. Dietary Supplement Fact Sheet: Magnesium. ODS. http://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/
About Rockwell Nutrition

Nutrition Consultations
with Julie Haugen,
MS,RD,LN/D



Sitemap
Copyright RockwellNutrition.com. All Rights Reserved.